Abstract: A method involves detecting in a sample an autoantibody binding specifically to one or more from Gluk1, Gluk2, Gluk3, Gluk4 and Gluk5, preferably Gluk2. An autoantibody binds specifically to one or more from Gluk1, Gluk2, Gluk3, Gluk4 and Gluk5, preferably Gluk2. A diagnostically useful carrier with a solid phase with an immobilized polypeptide contains one or more from Gluk1, Gluk2, Gluk3, Gluk4 and Gluk5, preferably Gluk2 or a variant thereof. The autoantibody can be used for diagnosing a neurological autoimmune disease or a cancer.
Type:
Application
Filed:
August 10, 2022
Publication date:
February 23, 2023
Applicants:
Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Institució Catalana de Recerca i Estudis Avançats (ICREA), Fundació Clinic per a la Recerca Biomèdica (FCRB)
Abstract: The method comprising acquiring and analyzing by computer means image information of video sequences of two or more dimensions obtained from contrast-enhanced signals, for example ultrasound, coherence tomography, fluorescence images, or Magnetic Resonance Imaging, of a body part or tissue, for example of an organ, of a living subject; detecting events from said information of video sequences; selecting a Region of Interest of said body part or tissue; computing a first graph representative of a local vascular network of said image information of video sequences in which the edges of the graph are estimated by the temporal relationship among spatially remote signals of said image information of video sequences within a set of video sequences; and using said graph for assessment of vascular networks.
Type:
Grant
Filed:
March 20, 2014
Date of Patent:
March 7, 2017
Assignees:
EXPERT YMAGING, S.L., HOSPITAL CLINIC I PROVINCIAL DE BARCELONA, FUNDACIO CLINIC PER A LA RECERCA BIOMEDICA (FCRB), UNIVERSITAT DE BARCELONA
Inventors:
Ivan Amat Roldan, Jaime Bosch Genover, Annalisa Berzigotti, Maria Rosa Gilabert Solé
Abstract: The present invention is related to 4-amino-6-(2,6-dichlorophenyl)-2-(phenylamino)-pyrido[2,3-d]pyrimidin-7(8H)-one derivatives, to the preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in the treatment and/or prevention of a non-Hodgkin's lymphoma.
Type:
Application
Filed:
June 16, 2014
Publication date:
June 23, 2016
Applicants:
INSTITUT QUÍMIC DE SARRIÁ, CETS FUNDACIÓ, PRIVADA, HOSPITAL CLÍNIC DE BARCELONA, FUNDACIÓ CLINIC PER A LA RECERCA BIOMÈDICA (FCRB), INSTITUT D'INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER
Inventors:
José Ignacio Borrell Bilbao, Jordi Teixido Closa, Raimon Puig De La Bellacasa Cazorla, Dolors Colomer Pujol, Gael Roue, Patricia Pérez-Galán
Abstract: The method comprising acquiring and analysing by computer means image information of video sequences of two or more dimensions obtained from contrast-enhanced signals, for example ultrasound, coherence tomography, fluorescence images, or Magnetic Resonance Imaging, of a body part or tissue, for example of an organ, of a living subject; detecting events from said information of video sequences; selecting a Region of Interest of said body part or tissue; computing a first graph representative of a local vascular network of said image information of video sequences in which the edges of the graph are estimated by the temporal relationship among spatially remote signals of said image information of video sequences within a set of video sequences; and using said graph for assessment of vascular networks.
Type:
Application
Filed:
March 20, 2014
Publication date:
February 11, 2016
Applicants:
EXPERT YMAGING, SL, HOSPITAL CLINIC I PROVINCIAL DE BARCELONA, UNIVERSITAT DE BARCELONA, FUNDACIÓ CLINIC PER A LA RECERCA BIOMÈDICA (FCRB), CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES HEPÁTICAS Y DIGESTIVA
Inventors:
Ivan AMAT ROLDAN, Jaime BOSCH GENOVER, Annalisa BERZIGOTTI, Maria Rosa GILABERT SOLÉ
Abstract: Equipment for infrared vision of anatomical structures applicable to assist the physicians in endoscopic, fetoscopic or laparoscopic operations and methods for signal processing to enhance said vision, comprising two units that work together: a multimodal or multispectral imaging unit, constituted by a device comprising an endoscope or fetoscope or laparoscope, and additional optical systems to acquire multimodal images of the interior of the patient's body; and an image processing unit, to which said images are transferred, comprising processing devices with a navigation interface which process said images and display the patient's enhanced anatomical map image and the endoscope location, equipped with hardware and software that apply at least five different vision-enhancing methods, namely normalization, segmentation, tracking, mapping and fusion.
Type:
Application
Filed:
December 10, 2009
Publication date:
December 1, 2011
Applicants:
Fundacio Clinic Per A La Recerca Biomedica Fcrb, Universitat De Barcelona, Hospital Clinic I Provincial De Barcelona
Inventors:
Eduard Gratacós Solsona, Iván Amat Roldán