Patents Assigned to GABA International Holding AG
  • Patent number: 9370479
    Abstract: A mouthrinse containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions, for use against erosive tooth demineralization, and kits containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions, wherein one of the two active agents is comprised in a mouthrinse, are described. The mouthrinse may furthermore comprise dissolved tin, in particular stannous ions. Mouthrinses containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions are tested in the treatment or prevention of erosive tooth demineralization caused by citric acid.
    Type: Grant
    Filed: February 18, 2011
    Date of Patent: June 21, 2016
    Assignee: GABA International Holding AG
    Inventors: Dally Moya Argilagos, Cornelia Scheffel, Turan Matur, Andre Brunella
  • Patent number: 9320691
    Abstract: Described herein are stable aqueous stannous ion containing compositions and methods of preparing and using the same.
    Type: Grant
    Filed: September 9, 2011
    Date of Patent: April 26, 2016
    Assignee: GABA International Holdings AG
    Inventors: Alan Carlo Ceresa, René Heckendorn, Madeleine Manns
  • Publication number: 20150366768
    Abstract: An oral care composition is provided. The composition comprises (a) a first component comprising an amine fluoride; and (b) a second component comprising an acidic polymer; wherein the amine fluoride and acidic polymer have respective first and second reactive groups which are arranged to react together to form a cross-linked copolymer of the amine fluoride and acidic polymer when the composition is applied to an oral cavity.
    Type: Application
    Filed: December 21, 2012
    Publication date: December 24, 2015
    Applicant: GABA International Holding AG
    Inventors: Angelique Hug, Tilo Poth, René Heckendorn
  • Publication number: 20150335540
    Abstract: The present application provides a packaged aqueous oral care composition comprising a container and a composition wherein the composition comprises at least one water-soluble source of Sn2+ ions and the container comprises an inner surface being at least partially formed from a linear polymer, wherein the linear polymer is a homopolymer or a copolymer of monomers having the structure: wherein R1 and R2 are the same or different and are independently selected from a hydrogen atom, an alkyl group, an alkenyl group, a halogen atom and a nitrile group.
    Type: Application
    Filed: December 24, 2012
    Publication date: November 26, 2015
    Applicant: GABA International Holding AG
    Inventors: Alan Carlo CERESA, René HECKENDORN
  • Patent number: 9102996
    Abstract: Disclosed herein are processes for oxidising Sn2+ dissolved in an aqueous solution to stannic compounds using NO2 and optionally O2 as oxidants, wherein the aqueous solution is kept at a pH in the range of 0 to 7, wherein a salt Sn2+(Xn?)2/n and the oxidants are used according to the reaction scheme a Sn2+(Xn?)2/n +b O2+c NO2??stannic compounds in which scheme a, b and c are mole numbers; with the proviso that when b is essentially zero, then the aqueous solution is essentially free of Cl?, HSO4? and SO42?.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: August 11, 2015
    Assignee: GABA International Holding AG
    Inventors: Alan C. Ceresa, Rene Heckendorn, Elisabeth Scherrer
  • Patent number: 8926950
    Abstract: An oral care composition comprising a) an aqueous phase; b) stannous ions solvated in the aqueous phase; c) nitrates solvated in the aqueous phase; wherein the total content of said nitrates is such that the molar amount of nitrogen in the aqueous phase, measurable as nitrate, is less than 2 times the molar amount of solvated stannous ions; and d) a flavor substance, which is preferably solvated, dispersed or emulgated in the aqueous phase. Disclosed are also containers containing the composition; and processes and uses for stabilizing stannous ions against oxidation, using nitrates.
    Type: Grant
    Filed: April 7, 2011
    Date of Patent: January 6, 2015
    Assignee: GABA International Holding AG
    Inventors: René Heckendorn, Alan Ceresa, Elisabeth Scherrer
  • Publication number: 20140370292
    Abstract: Disclosed herein are processes for oxidising Sn2+ dissolved in an aqueous solution to stannic compounds using NO2 and optionally O2 as oxidants, wherein the aqueous solution is kept at a pH in the range of 0 to 7, wherein a salt Sn2+(Xn?)2/n and the oxidants are used according to the reaction scheme a Sn2+(Xn?)2/n +b O2+c NO2??stannic compounds in which scheme a, b and c are mole numbers; with the proviso that when b is essentially zero, then the aqueous solution is essentially free of Cl?, HSO4? and SO42?.
    Type: Application
    Filed: December 22, 2011
    Publication date: December 18, 2014
    Applicant: GABA INTERNATIONAL HOLDING AG
    Inventors: Alan C. Ceresa, Rene Heckendorn, Elisabeth Scherrer
  • Publication number: 20140205549
    Abstract: Described herein are stable aqueous stannous ion containing compositions and methods of preparing and using the same.
    Type: Application
    Filed: September 9, 2011
    Publication date: July 24, 2014
    Applicant: GABA International Holding AG
    Inventors: Alan Carlo Ceresa, René Heckendorn, Madeleine Manns
  • Publication number: 20130319883
    Abstract: A mouthrinse containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions, for use against erosive tooth demineralization, and kits containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions, wherein one of the two active agents is comprised in a mouthrinse, are described. The mouthrinse may furthermore comprise dissolved tin, in particular stannous ions. Mouthrinses containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions are tested in the treatment or prevention of erosive tooth demineralisation caused by citric acid.
    Type: Application
    Filed: February 18, 2011
    Publication date: December 5, 2013
    Applicant: GABA INTERNATIONAL HOLDING AG
    Inventors: Dally Moya Argilagos, Cornelia Scheffel, Turan Matur, Andre Brunella
  • Publication number: 20130323186
    Abstract: A dentifrice, such as toothpaste, containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions, for use against erosive tooth demineralization, and kits containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions, wherein one of the two active agents is comprised in a dentifrice, are described. The dentifrice in the form of toothpaste may furthermore comprise dissolved tin, in particular stannous ions. Toothpastes containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions are tested in the treatment or prevention of erosive tooth demineralisation caused by citric acid.
    Type: Application
    Filed: February 18, 2011
    Publication date: December 5, 2013
    Applicant: GABA International Holding AG
    Inventors: Dally Moya Argilagos, Cornelia Scheffel, Turan Matur, Andre Brunella
  • Publication number: 20130209375
    Abstract: An oral care composition comprising a liquid phase containing 30% to 90%, preferably 30% to 80% by weight, based on the liquid phase, of water; dissolved tin; 200 to 2000 ppm fluoride ions, based on the oral composition; and 5 to 60% by weight, based on the oral care composition, of a C(3-5) sugar alcohol; characterised in that the content of dissolved tin [Sn] in the liquid phase is at least 750 ppm, preferably at least 1000 ppm, based on the composition; that 60 mol % or more, preferably 75 mol % or more of the content of dissolved tin [Sn] is in the formal oxidation state +II; and that the composition comprises an organic acid and ammonium cations of the Formula (I): R—NH+Ra—[(CH2)u—NH+Rb]v—Rc (I), wherein R is a saturated or unsaturated straight-chain hydrocarbon residue of 10 to 20 carbon atoms, v is an integer from 0 to 1, u is an integer from 2 to 3 and Ra, Rb and Rc are independently selected from hydrogen and —CH2CH2OH. The composition is preferably a mouthrinse.
    Type: Application
    Filed: April 24, 2009
    Publication date: August 15, 2013
    Applicant: GABA International Holding AG
    Inventors: Dally Moya Argilagos, Turan Matur, Cornelia Scheffel