Patents Assigned to GEM INNOV
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Publication number: 20240033702Abstract: Use of biodegradable microcapsules comprising a wall made of poly(beta-amino)ester, abbreviated to PBAE, which contains an active substance. These microcapsules may be obtained by a method of interfacial polymerization between an amine monomer and a multi-acrylate monomer. Depending on the intended use, microcapsules with a wall that is weak, breakable or unbreakable and porous or non-porous are used; these properties may be obtained by the choice of the monomers and the thickness of the wall. For certain uses, it is possible to use the polymerization reaction mixture directly, without washing.Type: ApplicationFiled: November 17, 2021Publication date: February 1, 2024Applicant: GEM INNOVInventors: Yohann GUILLANEUF, Catherine LEFAY, Didier GIGMES, The Hien HO, Kaouthar OUDOUA, Thierry RIBEIRO, Yves ORTAIS, Marie-Pierre CESBRON
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Publication number: 20240016751Abstract: Method for manufacturing microcapsules comprising a wall made of polymer material containing an active substance, comprising the following steps: —preparing an oil phase comprising a poly(beta-aminoester) prepolymer, and an active substance constituting the phase to be encapsulated; preparing an aqueous phase comprising at least one surfactant; preparing an O/W (oil in water) emulsion by adding the oil phase to the aqueous phase; and initiating radical polymerisation with in the emulsion. A polymerisation initiator must be present in the aqueous and/or oil phase.Type: ApplicationFiled: November 18, 2021Publication date: January 18, 2024Applicant: GEM INNOVInventors: Yohann GUILLANEUF, Catherine LEFAY, Didier GIGMES, The Hien HO, Kaouthar OUDOUA, Thierry RIBEIRO, Yves ORTAIS
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Patent number: 11654410Abstract: A method for manufacturing microcapsules containing an active substance, the method including: providing an aqueous solution of a surfactant, an oily phase comprising the active substance and a first monomer, and a polar phase comprising a second monomer; preparing an oil-in-water emulsion by adding the oily phase to the aqueous solution of the surfactant; adding the polar phase to the oil-in-water emulsion, in order to obtain a polymer in a reaction mixture, by polymerization of the first monomer and the second monomer; isolating the microcapsules, including a wall formed by the polymer and containing the active substance, from the reaction mixture; wherein the polymer is a poly(beta-amino ester). Microcapsules obtained by the method.Type: GrantFiled: May 16, 2020Date of Patent: May 23, 2023Assignee: GEM INNOVInventors: Yves Ortais, Thierry Ribeiro, Kaouthar Oudoua, The Hien Ho, Didier Gigmes, Catherine Guillaneuf, Yohann Guillaneuf
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Publication number: 20230021302Abstract: Method for manufacturing microcapsules enclosing a substance referred to as the active substance, in which method: there are provided an aqueous solution of a surfactant, an oily phase comprising the active substance and at least a first monomer X, and a polar phase having at least a second monomer Y; an O/W emulsion is prepared by adding the oily phase to the aqueous solution of the surfactant; the polar phase is added to the O/W emulsion in order to obtain a polymer by polymerisation of the X and Y monomers; starting from this reaction mixture, the microcapsules are isolated and comprise a wall which is formed by the polymer and which encloses the active substance; the polymer is a poly(beta-amino ester).Type: ApplicationFiled: May 14, 2020Publication date: January 19, 2023Applicants: GEM INNOV, UNIVERSITÉ D'AIX MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Yves ORTAIS, Thierry RIBEIRO, Kaouthar OUDOUA, The Hien HO, Didier GIGMES, Catherine GUILLANEUF, Yohann GUILLANEUF
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Publication number: 20220314185Abstract: Method for manufacturing microcapsules enclosing a substance referred to as the active substance, in which method: there are provided an aqueous solution of a surfactant, an oily phase comprising the active substance and at least a first monomer X, and a polar phase having at least a second monomer Y; an O/W emulsion is prepared by adding the oily phase to the aqueous solution of the surfactant; the polar phase is added to the O/W emulsion in order to obtain a polymer by polymerisation of the X and Y monomers; starting from this reaction mixture, the microcapsules are isolated and comprise a wall which is formed by the polymer and which encloses the active substance; the polymer is a poly(beta-amino ester).Type: ApplicationFiled: May 14, 2020Publication date: October 6, 2022Applicants: GEM INNOV, UNIVERSITÉ D'AIX MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Yves ORTAIS, Thierry RIBEIRO, Kaouthar OUDOUA, The Hien HO, Didier GIGMES, Catherine GUILLANEUF, Yohann GUILLANEUF
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Publication number: 20200360889Abstract: A method for manufacturing microcapsules containing an active substance, the method including: providing an aqueous solution of a surfactant, an oily phase comprising the active substance and a first monomer, and a polar phase comprising a second monomer; preparing an oil-in-water emulsion by adding the oily phase to the aqueous solution of the surfactant; adding the polar phase to the oil-in-water emulsion, in order to obtain a polymer in a reaction mixture, by polymerization of the first monomer and the second monomer; isolating the microcapsules, including a wall formed by the polymer and containing the active substance, from the reaction mixture; wherein the polymer is a poly(beta-amino ester). Microcapsules obtained by the method.Type: ApplicationFiled: May 16, 2020Publication date: November 19, 2020Applicants: GEM INNOV, UNIVERSITÉ D'AIX MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Yves ORTAIS, Thierry RIBEIRO, Kaouthar OUDOUA, The Hien HO, Didier GIGMES, Catherine GUILLANEUF, Yohann GUILLANEUF
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Patent number: 9464944Abstract: An indicator or display that may be in the form of a label that can instantaneously provide confirmation that a product is in a good preservation state by making a simple visual check, and particularly to detect if the product temporarily went outside a determined temperature range and to memorize this event. Strict monitoring of a temperature range is essential to be able to guarantee quality of many products. The indicator or display may be applicable to any product or device for which the temperature has to be monitored between two thresholds.Type: GrantFiled: January 25, 2013Date of Patent: October 11, 2016Assignee: GEM INNOVInventor: Yves Ortais