Abstract: Disclosed are compounds and methods for treating neurological and other disorders by administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for GFR? receptor molecules, which can be mimetics of glial-derived neurotrophic factor (GDNF) family ligands (GFLs), GFR?/RET signaling pathway agonists, and/or direct RET agonists (activators).
Type:
Grant
Filed:
December 13, 2010
Date of Patent:
December 2, 2014
Assignee:
GeneCode AS
Inventors:
Mart Saarma, Mati Karelson, Maxim Bespalov, Mehis Pilv
Abstract: Disclosed are compounds and methods for treating neurological and other disorders by administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for GFR? receptor molecules, which can be mimetics of glial-derived neurotrophic factor (GDNF) family ligands (GFLs), GFR?/RET signaling pathway agonists, and/or direct RET agonists (activators).
Type:
Application
Filed:
December 13, 2010
Publication date:
January 31, 2013
Applicant:
GeneCode AS
Inventors:
Mart Saarma, Mati Karelson, Maxim Bespalov, Mehis Pilv