Abstract: Provided herein are methods of preventing or reducing weight gain in a subject in need thereof by administering 2-acetylcyclopentane-1,3-dione (ACPD).
Type:
Grant
Filed:
October 11, 2017
Date of Patent:
June 23, 2020
Assignees:
University of South Florida, The United States Government as Represented by the Department of Veterans Affairs of General Counsel- PSG IV (024)
Inventors:
Robert Vito Farese, Mini Paliyath Sajan
Abstract: Methods and compositions for resuscitating, storing, and preserving functional integrity of organs and tissues. Metabolic function is maintained by sustaining ATP levels, mitochondrial function, cardiomyocyte contractility, prevention of acidosis, inhibition of induction of apoptosis, maintaining ionontrophy and lusiotrophy by regulating calcium, sodium, potassium and chloride ions.
Type:
Application
Filed:
June 5, 2012
Publication date:
October 18, 2012
Applicants:
President and Fellows of Harvard College, General Counsel-PSG IV (024)
Inventors:
Hemant Thatte, Patrick Treanor, Shukri F. Khuri, Randa Khuri, Laki Rousou