Patents Assigned to Genesoft Pharmaceuticals, Inc.
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Publication number: 20110178074Abstract: The present invention is related to methods of treating bacterial infections in mammals using antipathogenic benzamide compounds having the formula wherein at least one of the R1 groups is F, Cl, CN or CF3 and R2, R3, Y, Z, m, and n are as defined herein.Type: ApplicationFiled: January 25, 2008Publication date: July 21, 2011Applicant: GeneSoft Pharmaceuticals, Inc.Inventors: Roland W. BURLI, Jacob Kaizerman, Peter Jones
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Publication number: 20090247513Abstract: Benzothiophene compounds such as are DNA binding compounds exhibiting antibacterial activity.Type: ApplicationFiled: December 4, 2007Publication date: October 1, 2009Applicant: GeneSoft Pharmaceuticals, Inc.Inventors: Roland W. Burli, Eldon E. Baird, Matthew J. Taylor, Jacob A. Kaizerman, Wenhao Hu
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Patent number: 7498349Abstract: Aromatic compounds exemplified by exhibit antimicrobial activity.Type: GrantFiled: August 1, 2003Date of Patent: March 3, 2009Assignee: Genesoft Pharmaceuticals, Inc.Inventors: Roland W. Burli, Eldon E. Baird, Jacob A. Kaizerman, Dustin L. McMinn
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Patent number: 7498405Abstract: Halogen substituted thienyl compounds exhibit potential as nucleic acid (especially double stranded DNA) binders and as antibiotic compounds.Type: GrantFiled: June 2, 2006Date of Patent: March 3, 2009Assignee: GeneSoft Pharmaceuticals, Inc.Inventors: Yigong Ge, Matthew J. Taylor, Eldon E. Baird, Roland W. Burli, Jacob A. Kaizerman, Amanda E. Martin, Brie Cadman
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Publication number: 20080200465Abstract: The present invention is related to methods of treating viral and protozoan infections in mammals using antipathogenic benzamide compounds having the formula wherein at least one of the R1 groups is F, Cl, CN or CF3 and R2, R3, Y, Z, m, and n are as defined herein.Type: ApplicationFiled: January 25, 2008Publication date: August 21, 2008Applicant: GeneSoft Pharmaceuticals, Inc.Inventors: Roland W. BURLI, Jacob Kaizerman, Peter Jones
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Publication number: 20080090816Abstract: Compounds represented by the formula where R1, R2, R3, R4, R5, and Q are as defined herein, exhibit activity against infectious pathogens.Type: ApplicationFiled: August 2, 2007Publication date: April 17, 2008Applicant: Genesoft Pharmaceuticals, Inc.Inventors: Peter Jones, Roland Burli, Chun Jiang, Dustin McMinn
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Patent number: 7348427Abstract: Antipathogenic benzamide compounds having the formula wherein at least one of the R1 groups is F, Cl, CN or CF3 and R2, R3, Y, Z, m, and n are as defined herein.Type: GrantFiled: December 2, 2004Date of Patent: March 25, 2008Assignee: Genesoft Pharmaceuticals, Inc.Inventors: Roland W. Bürli, Jacob Kaizerman, Peter Jones
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Patent number: 7329765Abstract: Benzothiophene compounds such as are DNA binding compounds exhibiting antibacterial activity.Type: GrantFiled: November 30, 2004Date of Patent: February 12, 2008Assignee: GeneSoft Pharmaceuticals, Inc.Inventors: Roland W. Burli, Eldon E. Baird, Matthew J. Taylor, Jacob A. Kaizerman, Wenhao Hu
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Patent number: 7265129Abstract: Compounds represented by the formula (I), where R1, R2, R3, R4, R5, and Q are as defined herein, exhibit activity against infectious pathogensType: GrantFiled: October 24, 2003Date of Patent: September 4, 2007Assignee: Genesoft Pharmaceuticals, Inc.Inventors: Peter Jones, Roland W. Burli, Chun Jiang, Dustin L. McMinn
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Publication number: 20070105135Abstract: Charged compounds are provided that comprise one or more regions of localized positive charge, compositions comprising such compounds, methods of synthesizing such compounds, methods of screening such compounds to identify those having anti-infective activity, and methods of using such compounds to prevent or inhibit infections. These compounds, and compositions containing them, have multiple applications, including use in human and animal medicine and in agriculture.Type: ApplicationFiled: July 14, 2006Publication date: May 10, 2007Applicants: GeneSoft Pharmaceuticals, Inc., Genesoft, Inc.Inventors: Yigong Ge, Matthew Taylor, Eldon Baird, Heinz Moser, Roland Burli
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Publication number: 20060287247Abstract: Halogen substituted thienyl compounds exhibit potential as nucleic acid (especially double stranded DNA) binders and as antibiotic compounds.Type: ApplicationFiled: June 2, 2006Publication date: December 21, 2006Applicant: GeneSoft Pharmaceuticals, Inc.Inventors: Yigong Ge, Matthew Taylor, Eldon Baird, Roland Burli, Jacob Kaizerman, Amanda Martin, Brie Cadman
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Patent number: 7078536Abstract: Charged compounds are provided that comprise one or more regions of localized positive charge, compositions comprising such compounds, methods of synthesizing such compounds, methods of screening such compounds to identify those having anti-infective activity, and methods of using such compounds to prevent or inhibit infections. These compounds, and compositions containing them, have multiple applications, including use in human and animal medicine and in agriculture.Type: GrantFiled: October 22, 2002Date of Patent: July 18, 2006Assignee: Genesoft Pharmaceuticals, Inc.Inventors: Yigong Ge, Matthew J. Taylor, Eldon E. Baird, Heinz E. Moser, Roland W. Bürli
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Publication number: 20060148845Abstract: Compounds represented by the formula (I), where R1, R2, R3, R4, R5, and Q are as defined herein, exhibit activity against infectious pathogens.Type: ApplicationFiled: October 24, 2003Publication date: July 6, 2006Applicant: Genesoft Pharmaceuticals, Inc.Inventors: Peter Jones, Roland Burli, Chun Jiang, Dustin McMinn
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Publication number: 20060128747Abstract: Aromatic compounds exemplified by exhibit antimicrobial activity.Type: ApplicationFiled: August 1, 2003Publication date: June 15, 2006Applicant: GENESOFT PHARMACEUTICALS,INC.Inventors: Roland Burli, Eldon Baird, Jacob Kaizerman, Dustin McMinn
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Publication number: 20060116326Abstract: Benzothiophene compounds such as are DNA binding compounds exhibiting antibacterial activity.Type: ApplicationFiled: November 30, 2004Publication date: June 1, 2006Applicant: GeneSoft Pharmaceuticals, Inc.Inventors: Roland Burli, Eldon Baird, Matthew Taylor, Jacob Kaizerman, Wenhao Hu
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Publication number: 20060069034Abstract: Antipathogenic benzamide compounds having the formula wherein at least one of the R1 groups is F, Cl, CN or CF3 and R2, R3, Y, Z, m, and n are as defined herein.Type: ApplicationFiled: December 2, 2004Publication date: March 30, 2006Applicant: GeneSoft Pharmaceuticals, Inc.Inventors: Roland Burli, Jacob Kaizerman, Peter Jones
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Patent number: 6825228Abstract: Benzothiophene compounds such as are DNA binding compounds exhibiting antibacterial activity.Type: GrantFiled: June 6, 2002Date of Patent: November 30, 2004Assignee: Genesoft Pharmaceuticals, Inc.Inventors: Roland W. Bürli, Eldon E. Baird, Matthew J. Taylor, Jacob A. Kaizerman, Wenhao Hu
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Patent number: 6777425Abstract: Isoquinoline compounds having the formula where R1, R2, Y, m, n, and Z are as defined herein, bind to the minor groove of DNA and have antifungal and antibacterial activity.Type: GrantFiled: June 6, 2002Date of Patent: August 17, 2004Assignee: Genesoft Pharmaceuticals, Inc.Inventors: Roland W. Bürli, Peter Jones, Jacob A. Kaizerman, Wenhao Hu
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Patent number: 6716866Abstract: Aryl-benzimidazole compounds according to the formula where Ar1, R1, R2, Y, W, and N are as defined herein, bind to DNA and have antibacterial activity.Type: GrantFiled: June 6, 2002Date of Patent: April 6, 2004Assignee: GeneSoft Pharmaceuticals, Inc.Inventors: Dustin L. McMinn, Roland W. Bürli, Jacob Kaizerman, Eldon E. Baird, Matthew J. Taylor