Patents Assigned to GENO LLC
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Patent number: 8211368Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.Type: GrantFiled: May 23, 2011Date of Patent: July 3, 2012Assignee: Geno LLCInventors: David H. Fine, David P. Rounbehler, Gregory B. Vasquez
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Patent number: 8187544Abstract: Various systems, devices, NO2 absorbents, NO2 scavengers and NO2 recuperator for generating nitric oxide are disclosed herein. According to one embodiment, an apparatus for converting nitrogen dioxide to nitric oxide can include a receptacle including an inlet, an outlet, a surface-active material coated with an aqueous solution of ascorbic acid and an absorbent wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the surface-active material and the absorbent such that nitrogen dioxide in the gas flow is converted to nitric oxide.Type: GrantFiled: March 25, 2011Date of Patent: May 29, 2012Assignee: Geno LLCInventors: David Fine, Gregory Vasquez, David P. Rounbehler
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Patent number: 8173072Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.Type: GrantFiled: September 21, 2009Date of Patent: May 8, 2012Assignee: Geno LLCInventors: David H. Fine, David P. Rounbehler, Gregory Vasquez, Bryan Johnson
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Patent number: 8083997Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. A nitric oxide delivery system that converts nitrogen dioxide to nitric oxide employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid.Type: GrantFiled: July 10, 2009Date of Patent: December 27, 2011Assignee: Geno LLCInventors: David R. Rounbehler, David H. Fine
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Patent number: 8066904Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.Type: GrantFiled: August 28, 2002Date of Patent: November 29, 2011Assignee: Geno LLCInventors: David H. Fine, Stephen J. MacDonald, David Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
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Patent number: 8057742Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.Type: GrantFiled: November 17, 2009Date of Patent: November 15, 2011Assignee: Geno LLCInventors: David R. Rounbehler, David H. Fine
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Publication number: 20110259325Abstract: A system for deliverying a therapeutic amount of nitric oxide can include a reservoir assembly, a gas supply, and a delivery conduit including a first cartridge, wherein the first cartridge can include a surface-activated material saturated with an aqueous solution of a reducing agent.Type: ApplicationFiled: April 26, 2011Publication date: October 27, 2011Applicant: GeNO LLCInventors: David H. Fine, Gregory Vasquez, Bryan Johnson, Ryan Denton, Lucas G. Gamero
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Publication number: 20110262335Abstract: A unique combination of male and female gas connectors for one way transfer of gasses.Type: ApplicationFiled: April 26, 2011Publication date: October 27, 2011Applicant: GeNO LLCInventors: Jody Fuller, David H. Fine
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Publication number: 20110240019Abstract: Methods and systems of using liquid nitrogen dioxide (N2O4) with a ventilator can generate and deliver nitric oxide to a patient by means of a ventilator.Type: ApplicationFiled: January 31, 2011Publication date: October 6, 2011Applicant: GeNO LLCInventors: David H. Fine, Ryan Denton, Gregory Vasquez, Bryan Johnson
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Publication number: 20110220103Abstract: An ambulatory or stationary device for delivery of a therapeutic amount of nitric oxide to an individual's lungs.Type: ApplicationFiled: November 22, 2010Publication date: September 15, 2011Applicant: GeNO LLCInventors: David H. Fine, Gregory Vasquez, Bryan Johnson, Jody Fuller, Ryan Denton
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Patent number: 7947227Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.Type: GrantFiled: March 21, 2008Date of Patent: May 24, 2011Assignee: Geno LLCInventors: David H. Fine, David P. Rounbehler, Greg Vasquez
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Patent number: 7914743Abstract: Various systems, devices, NO2 absorbents, NO2 scavengers and NO2 recuperator for generating nitric oxide are disclosed herein. According to one embodiment, an apparatus for converting nitrogen dioxide to nitric oxide can include a receptacle including an inlet, an outlet, a surface-active material coated with an aqueous solution of ascorbic acid and an absorbent wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the surface-active material and the absorbent such that nitrogen dioxide in the gas flow is converted to nitric oxide.Type: GrantFiled: January 28, 2009Date of Patent: March 29, 2011Assignee: Geno LLCInventors: David Fine, Gregory Vasquez, David P. Rounbehler
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Publication number: 20100323036Abstract: A method for delivering nitric oxide therapy to a subject can include administering a composition including a nitric-oxide releasing agent and silica to the subject and releasing a therapeutic amount of nitric oxide from the composition.Type: ApplicationFiled: June 21, 2010Publication date: December 23, 2010Applicant: GeNO LLCInventor: David H. Fine
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Publication number: 20100104667Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.Type: ApplicationFiled: September 21, 2009Publication date: April 29, 2010Applicant: GeNO LLCInventors: David H. Fine, David P. Rounbehler, Gregory Vasquez
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Patent number: 7618594Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.Type: GrantFiled: March 7, 2006Date of Patent: November 17, 2009Assignee: GeNO LLCInventors: David R. Rounbehler, David H. Fine
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Patent number: 7560076Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. A nitric oxide delivery system that converts nitrogen dioxide to nitric oxide employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid.Type: GrantFiled: August 18, 2005Date of Patent: July 14, 2009Assignee: GENO LLCInventors: David R. Rounbehler, David H. Fine
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Publication number: 20080317874Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.Type: ApplicationFiled: March 21, 2008Publication date: December 25, 2008Applicant: GeNO LLCInventors: David H. Fine, David P. Rounbehler, Greg Vasquez
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Publication number: 20070089739Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.Type: ApplicationFiled: May 8, 2006Publication date: April 26, 2007Applicant: GENO LLCInventors: David Fine, Stephen MacDonald, David Rounbehler, David Wheeler, Jonathan Rolfe, George Jarvis
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Publication number: 20060172018Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.Type: ApplicationFiled: April 7, 2006Publication date: August 3, 2006Applicant: GENO LLCInventors: David Fine, Stephen MacDonald, David Rounbehler, David Wheeler, Jonathan Rolfe, George Jarvis