Patents Assigned to GENO LLC
  • Patent number: 8211368
    Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.
    Type: Grant
    Filed: May 23, 2011
    Date of Patent: July 3, 2012
    Assignee: Geno LLC
    Inventors: David H. Fine, David P. Rounbehler, Gregory B. Vasquez
  • Patent number: 8187544
    Abstract: Various systems, devices, NO2 absorbents, NO2 scavengers and NO2 recuperator for generating nitric oxide are disclosed herein. According to one embodiment, an apparatus for converting nitrogen dioxide to nitric oxide can include a receptacle including an inlet, an outlet, a surface-active material coated with an aqueous solution of ascorbic acid and an absorbent wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the surface-active material and the absorbent such that nitrogen dioxide in the gas flow is converted to nitric oxide.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: May 29, 2012
    Assignee: Geno LLC
    Inventors: David Fine, Gregory Vasquez, David P. Rounbehler
  • Patent number: 8173072
    Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.
    Type: Grant
    Filed: September 21, 2009
    Date of Patent: May 8, 2012
    Assignee: Geno LLC
    Inventors: David H. Fine, David P. Rounbehler, Gregory Vasquez, Bryan Johnson
  • Patent number: 8083997
    Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. A nitric oxide delivery system that converts nitrogen dioxide to nitric oxide employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid.
    Type: Grant
    Filed: July 10, 2009
    Date of Patent: December 27, 2011
    Assignee: Geno LLC
    Inventors: David R. Rounbehler, David H. Fine
  • Patent number: 8066904
    Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.
    Type: Grant
    Filed: August 28, 2002
    Date of Patent: November 29, 2011
    Assignee: Geno LLC
    Inventors: David H. Fine, Stephen J. MacDonald, David Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
  • Patent number: 8057742
    Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.
    Type: Grant
    Filed: November 17, 2009
    Date of Patent: November 15, 2011
    Assignee: Geno LLC
    Inventors: David R. Rounbehler, David H. Fine
  • Publication number: 20110259325
    Abstract: A system for deliverying a therapeutic amount of nitric oxide can include a reservoir assembly, a gas supply, and a delivery conduit including a first cartridge, wherein the first cartridge can include a surface-activated material saturated with an aqueous solution of a reducing agent.
    Type: Application
    Filed: April 26, 2011
    Publication date: October 27, 2011
    Applicant: GeNO LLC
    Inventors: David H. Fine, Gregory Vasquez, Bryan Johnson, Ryan Denton, Lucas G. Gamero
  • Publication number: 20110262335
    Abstract: A unique combination of male and female gas connectors for one way transfer of gasses.
    Type: Application
    Filed: April 26, 2011
    Publication date: October 27, 2011
    Applicant: GeNO LLC
    Inventors: Jody Fuller, David H. Fine
  • Publication number: 20110240019
    Abstract: Methods and systems of using liquid nitrogen dioxide (N2O4) with a ventilator can generate and deliver nitric oxide to a patient by means of a ventilator.
    Type: Application
    Filed: January 31, 2011
    Publication date: October 6, 2011
    Applicant: GeNO LLC
    Inventors: David H. Fine, Ryan Denton, Gregory Vasquez, Bryan Johnson
  • Publication number: 20110220103
    Abstract: An ambulatory or stationary device for delivery of a therapeutic amount of nitric oxide to an individual's lungs.
    Type: Application
    Filed: November 22, 2010
    Publication date: September 15, 2011
    Applicant: GeNO LLC
    Inventors: David H. Fine, Gregory Vasquez, Bryan Johnson, Jody Fuller, Ryan Denton
  • Patent number: 7947227
    Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.
    Type: Grant
    Filed: March 21, 2008
    Date of Patent: May 24, 2011
    Assignee: Geno LLC
    Inventors: David H. Fine, David P. Rounbehler, Greg Vasquez
  • Patent number: 7914743
    Abstract: Various systems, devices, NO2 absorbents, NO2 scavengers and NO2 recuperator for generating nitric oxide are disclosed herein. According to one embodiment, an apparatus for converting nitrogen dioxide to nitric oxide can include a receptacle including an inlet, an outlet, a surface-active material coated with an aqueous solution of ascorbic acid and an absorbent wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the surface-active material and the absorbent such that nitrogen dioxide in the gas flow is converted to nitric oxide.
    Type: Grant
    Filed: January 28, 2009
    Date of Patent: March 29, 2011
    Assignee: Geno LLC
    Inventors: David Fine, Gregory Vasquez, David P. Rounbehler
  • Publication number: 20100323036
    Abstract: A method for delivering nitric oxide therapy to a subject can include administering a composition including a nitric-oxide releasing agent and silica to the subject and releasing a therapeutic amount of nitric oxide from the composition.
    Type: Application
    Filed: June 21, 2010
    Publication date: December 23, 2010
    Applicant: GeNO LLC
    Inventor: David H. Fine
  • Publication number: 20100104667
    Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.
    Type: Application
    Filed: September 21, 2009
    Publication date: April 29, 2010
    Applicant: GeNO LLC
    Inventors: David H. Fine, David P. Rounbehler, Gregory Vasquez
  • Patent number: 7618594
    Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.
    Type: Grant
    Filed: March 7, 2006
    Date of Patent: November 17, 2009
    Assignee: GeNO LLC
    Inventors: David R. Rounbehler, David H. Fine
  • Patent number: 7560076
    Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. A nitric oxide delivery system that converts nitrogen dioxide to nitric oxide employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid.
    Type: Grant
    Filed: August 18, 2005
    Date of Patent: July 14, 2009
    Assignee: GENO LLC
    Inventors: David R. Rounbehler, David H. Fine
  • Publication number: 20080317874
    Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.
    Type: Application
    Filed: March 21, 2008
    Publication date: December 25, 2008
    Applicant: GeNO LLC
    Inventors: David H. Fine, David P. Rounbehler, Greg Vasquez
  • Publication number: 20070089739
    Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.
    Type: Application
    Filed: May 8, 2006
    Publication date: April 26, 2007
    Applicant: GENO LLC
    Inventors: David Fine, Stephen MacDonald, David Rounbehler, David Wheeler, Jonathan Rolfe, George Jarvis
  • Publication number: 20060172018
    Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.
    Type: Application
    Filed: April 7, 2006
    Publication date: August 3, 2006
    Applicant: GENO LLC
    Inventors: David Fine, Stephen MacDonald, David Rounbehler, David Wheeler, Jonathan Rolfe, George Jarvis