Patents Assigned to Genomine, Inc.
  • Patent number: 8278058
    Abstract: Disclosed herein are a composition and a kit for diagnosing renal cell carcinoma. The composition and kit employ, as a renal cell carcinoma marker, nicotinamide N-methyltransferase, L-plastin, secretagogin, NM23A, CapG, which is an actin regulatory protein, and/or C4a anaphylatoxin.
    Type: Grant
    Filed: August 6, 2008
    Date of Patent: October 2, 2012
    Assignees: DCD Inc., Genomine, Inc.
    Inventors: Dong Su Kim, Nam Hoon Cho, Hyung Jin Na, Young Deuk Choi, Jae Ho Jang, Hye-Kyung Kim, Mo Yoel Park, Won Man Park, Tae-hoon Kim, Dong Hee Lee, Kyung Mok Park
  • Patent number: 8003340
    Abstract: Disclosed herein a method and a kit for fractioning/isolating phosphoproteins. Calcium ions, barium ions, cobalt ions and molybdenum ions are bound specifically to phosphoproteins to form metal-phosphoprotein complexes. They can be easily precipitated with precipitants including sulfates, citrates, bicarbonates and carbonates.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: August 23, 2011
    Assignees: DCD Inc., Genomine, Inc.
    Inventors: Dong Su Kim, Hyung Jin Na, Jae Ho Jang, Hye-Kyung Kim, Mo Yoel Park
  • Publication number: 20110131683
    Abstract: Provided are polypeptides capable of inducing dwarfism in plants, polynucleotides encoding the same, and uses thereof.
    Type: Application
    Filed: November 13, 2008
    Publication date: June 2, 2011
    Applicant: GENOMINE, INC.
    Inventors: Dong-Hee Lee, Kook-Jin Kim, Dong-Su Kim
  • Publication number: 20100297661
    Abstract: Disclosed herein are a composition and a kit for diagnosing renal cell carcinoma. The composition and kit employ, as a renal cell carcinoma marker, nicotinamide N-methyltransferase, L-plastin, secretagogin, NM23A, CapG, which is an actin regulatory protein, and/or C4a anaphylatoxin.
    Type: Application
    Filed: August 6, 2008
    Publication date: November 25, 2010
    Applicants: DCD INC., GENOMINE, INC.
    Inventors: Dong Su Kim, Nam Hoon Cho, Hyung Jin Na, Young Deuk Choi, Jae Ho Jang, Hye-Kyung Kim, Mo Yoel Park, Won Man Park, Tae-hoon Kim, Dong Hee Lee, Kyung Mok Park
  • Publication number: 20100233784
    Abstract: Disclosed herein a method and a kit for fractioning/isolating phosphoproteins. Calcium ions, barium ions, cobalt ions and molybdenum ions are bound specifically to phosphoproteins to form metal-phosphoprotein complexes. They can be easily precipitated with precipitants including sulfates, citrates, bicarbonates and carbonates.
    Type: Application
    Filed: June 20, 2008
    Publication date: September 16, 2010
    Applicants: DCD INC., GENOMINE, INC.
    Inventors: Dong Su Kim, Hyung Jin Na, Jae Ho Jang, Hye-Kyung Kim, Mo Yoel Park
  • Patent number: 7795501
    Abstract: A novel protein, ORE 15, responsible for the regulation of plant leaf longevity is disclosed. Also, a gene encoding the protein ORE15 is disclosed. The protein and gene can be used in the regulation of plant leaf longevity, including delayed senescence, growth promotion, leaf weight, an size increase.
    Type: Grant
    Filed: August 31, 2005
    Date of Patent: September 14, 2010
    Assignees: Genomine, Inc., Postech Foundation
    Inventors: Hong-gil Nam, Jin-hee Kim, Hye-ryun Woo
  • Patent number: 7728193
    Abstract: The present invention relates to a novel protein interacting with phytochromes and use thereof, and more particularly, to a polypeptide having either an amino acid sequence set forth in SEQ ID NO: 4 or an amino acid sequence having at least 70% with said amino acid sequence, and use thereof. The polypeptide interacts with phytochromes A and B, and the TPR domain present at the N-terminal region of the polypeptide is involved in the interaction. Also, a PP2A catalytic domain (PP2Ac) having phosphatase activity is present at the C-terminal region of the polypeptide. The polypeptide can be used as a phosphatase, and is useful in the production of plants sensitive to light signal transduction. Furthermore, the TPR domain present in the polypeptide is useful in the production of dwarf plants.
    Type: Grant
    Filed: February 28, 2005
    Date of Patent: June 1, 2010
    Assignees: Genomine Inc., Postech Foundation
    Inventors: Hong-Gil Nam, Jong-Sang Ryu, Pyung-Ok Lim, Ja-Choon Koo
  • Publication number: 20100037345
    Abstract: Disclosed herein are a polypeptide having a methionine synthesis function, a polynucleotide encoding the same, and uses thereof.
    Type: Application
    Filed: December 20, 2007
    Publication date: February 11, 2010
    Applicants: GENOMINE, INC., KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Dong Hee Lee, Tae-hoon Kim, Kook Jin Kim, Jong Bo Kim, Kyung Mok Park, In Taek Hwang, No Joong Park
  • Publication number: 20090133153
    Abstract: The present invention discloses a polypeptide participating in pyridoxine biosynthesis, a polynucleotide coding the polypeptide and those uses. Particularly, this present invention discloses a polypeptide participating in pyridoxine biosynthesis, a polynucleotide coding the polypeptide, a method for inducing plant growth inhibition, a method for screening a compound inducing plant growth inhibition, and composition for inducing plant growth inhibition which comprises the compound obtained by the screening method.
    Type: Application
    Filed: February 18, 2005
    Publication date: May 21, 2009
    Applicant: Genomine, Inc
    Inventors: Dong-hee Lee, Tae-Hoon Kim, In-taek Hwang, Kwang-yun Oho
  • Publication number: 20080235826
    Abstract: The present invention relates to a novel protein interacting with phytochromes and use thereof, and more particularly, to a polypeptide having either an amino acid sequence set forth in SEQ ID NO: 4 or an amino acid sequence having at least 70% with said amino acid sequence, and use thereof. The polypeptide interacts with phytochromes A and B, and the TPR domain present at the N-terminal region of the polypeptide is involved in the interaction. Also, a PP2A catalytic domain (PP2Ac) having phosphatase activity is present at the C-terminal region of the polypeptide. The polypeptide can be used as a phosphatase, and is useful in the production of plants sensitive to light signal transduction. Furthermore, the TPR domain present in the polypeptide is useful in the production of dwarf plants.
    Type: Application
    Filed: February 28, 2005
    Publication date: September 25, 2008
    Applicants: Genomine Inc., Poatech Foundation
    Inventors: Hong-Gil Nam, Jong-Sang Ryu, Pyung-Ok Lim, Ja-Choon Koo
  • Publication number: 20080216197
    Abstract: Disclosed herein are a polypeptide having a pyridoxine biosynthesis-related function, a polypeptide encoding the same, and uses thereof.
    Type: Application
    Filed: February 1, 2006
    Publication date: September 4, 2008
    Applicants: Genomine, Inc., Korean Research Instittute Of Chemcial Technology
    Inventors: Dong-hee Lee, In-taek Hwang, Kwang-yun Cho, Tae-hoon Kim
  • Publication number: 20080134354
    Abstract: A novel protein, ORE 15, responsible for the regulation of plant leaf longevity is disclosed. Also, a gene encoding the protein ORE15 is disclosed. The protein and gene can be used in the regulation of plant leaf longevity, including delayed senescence, growth promotion, leaf weight, an size increase.
    Type: Application
    Filed: August 31, 2005
    Publication date: June 5, 2008
    Applicants: GENOMINE, INC., POSTECH FOUNDATION
    Inventors: Hong-gil Nam, Jin-hee Kim, Hye-ryun Woo
  • Publication number: 20080005813
    Abstract: The present invention discloses a polypeptide having function of cinnamyl alcohol dehydrogenase, a polynucleotide coding the polypeptide and those uses. Particularly, this present invention discloses a polypeptide having function of cinnamyl alcohol dehydrogenase, a polynucleotide coding the polypeptide, a method for inducing plant growth inhibition, a method for screening a compound inducing plant growth inhibition, and composition for inducing plant growth inhibition which comprises the compound obtained by the screening method.
    Type: Application
    Filed: February 18, 2005
    Publication date: January 3, 2008
    Applicant: GENOMINE, INC.
    Inventors: Dong-hee Lee, Tae-Hoon Kim, In-taek Hwang, Kwang-yun Cho, Jung-sup Choi, Kwan-hwi Lee, Bum-tae Kim
  • Patent number: 7217855
    Abstract: The present invention relates to a gene regulating flowering time and a method for regulating flowering time in plants using the same. More particularly, the present invention relates to a COG gene having nucleotide sequence represented by SEQ ID No: 1 which is isolated from Arabidopsis thaliana, and a method for delaying flowering time of plants by overexpressing the gene, or for inducing early flowering by repressing an expression of the gene. The COG gene and the COG protein expressed therefrom according to the present invention are useful for improvement of flowering-associated character of plants, and for identification of flowering-associated genes or proteins in other plants, etc.
    Type: Grant
    Filed: August 22, 2002
    Date of Patent: May 15, 2007
    Assignees: Postech Foundation, Genomine, Inc.
    Inventors: Don-Ha Park, Hong-Gil Nam, Pyung-Ok Lim
  • Patent number: 7141720
    Abstract: The present invention relates to a transcription factor of a plant, AtSIZ, induced by osmotic stress; a gene encoding the transcription factor; and a method for enhancing resistance to stress of a plant by using the gene. The AtSIZ protein isolated from Arabidopsis thaliana is a polypeptide, which contains a C3H-type zinc finger motif and acts as a transcription regulation factor activating transcription of genes related to stress response of a plant. Therefore, a plant with the enhanced resistance to osmotic stress can be produced by over expressing the AtSIZ gene in the plant through transforming recombinant plasmid containing AtSIZ gene into a plant and consequently, the productivity of the plant can be increased.
    Type: Grant
    Filed: March 9, 2001
    Date of Patent: November 28, 2006
    Assignee: Genomine, Inc.
    Inventors: Inhwan Hwang, Hai Lan Piao
  • Publication number: 20060168675
    Abstract: The invention relates to a novel polypeptide participating in biotin biosynthesis of plant, a polynucleotide encoding the said polypeptide, a method for inducing plant growth inhibition by suppressing the expression or function of the said polypeptide, resulting in inhibition of biotin biosynthesis, and a method for identifying herbicidal compounds that inhibit the expression or function of the said polypeptide. Biotin biosynthesis is an essential process for the growth of plants, however, the process is not present in both human and animals. Therefore, the compounds suppressing the expression or function of the novel polypeptide that relates to biotin biosynthesis can be effectively used as a new herbicide doing human and animals no harm.
    Type: Application
    Filed: July 2, 2003
    Publication date: July 27, 2006
    Applicant: GENOMINE, INC
    Inventors: Dong-Hee Lee, In-Taek Hwang, Jung-Sup Choi, Yong-Ki Min, Tae-Joon Kim, Jae-Heung Ko, Tae-Hoon Kim, Yu-Shin Park, Kwang-Yun Cho, Seon-Woo Lee
  • Patent number: 7060875
    Abstract: The present invention relates to a gene regulating leaf longevity of plants and a method for regulating the longevity of plants using the same. More particularly, it relates to a ORE7 gene regulating leaf longevity of plants which has a nucleotide sequence represented by SEQ ID NO: 1, and to a method for regulating the longevity of plants, in which the ORE7 gene is introduced into the plants and overexpressed, thereby delaying senescence of the plants. Plants can be transformed with ORE7 gene according to the present invention, so that the longevity of the plants is extended, thereby improving productivity and storage efficiency of the plants. Furthermore, the ORE7 gene and an ORE7 protein expressed therefrom according to the present invention are useful for studies of senescence mechanisms, and for identification of senescence-associated genes or senescence inhibitory substances, in plants.
    Type: Grant
    Filed: August 22, 2002
    Date of Patent: June 13, 2006
    Assignees: Postech Foundation, Genomine, Inc.
    Inventors: Pyung-Ok Lim, Hong-Gil Nam, Sung-Whan Cho
  • Publication number: 20050183166
    Abstract: The present invention relates to a gene regulating flowering time and a method for regulating flowering time in plants using the same. More particularly, the present invention relates to a COG gene having nucleotide sequence represented by SEQ ID No: 1 which is isolated from Arabidopsis thaliana, and a method for delaying flowering time of plants by overexpressing the gene, or for inducing early flowering by repressing an expression of the gene. The COG gene and the COG protein expressed therefrom according to the present invention are useful for improvement of flowering-associated character of plants, and for identification of flowering-associated genes or proteins in other plants, etc.
    Type: Application
    Filed: August 22, 2002
    Publication date: August 18, 2005
    Applicants: POSTECH FOUNDATION, GENOMINE, INC.
    Inventors: Don-Ha Park, Hong-Gil Nam, Pyung-Ok Lim
  • Patent number: 6444805
    Abstract: The oral vaccine of the present invention containing the HPV like particles is produced in edible transgenic plants and then administered through the consumption of the edible portion of those plants or after the purification of the particles. A DNA sequence encoding one of the HPV capsid proteins is isolated, inserted into the plasmid which comprises a plant-specific promoter and a gene for a selection marker, and then transferred to plant cells to give transgenic plants. Since the gene is expressed in a portion of the plants, the oral vaccine of the present invention can be produced in an inexpensive manner and administered in a simple method.
    Type: Grant
    Filed: February 24, 2000
    Date of Patent: September 3, 2002
    Assignee: Genomine, Inc.
    Inventors: Ulk Sohn, Hong Gil Nam, Deok Hoon Park, Kuk Hyun Kim