Patents Assigned to Genovoxx GmbH
  • Conjugates of nucleotides and method for the application thereof
    Patent number: 9315860
    Abstract: The invention relates to a novel method for enzymatically marking nucleic acid chains (target sequences) by using nucleotide conjugates. Said nucleotide conjugates are capable of binding specifically to the target sequence under reaction conditions and of being incorporated in the complementary growing strand by means of a polymerase. The nucleic acid chains marked with such conjugates can be bound to the solid phase. The marking can be carried out in parallel with the enzymatic amplification of target sequences.
    Type: Grant
    Filed: October 26, 2010
    Date of Patent: April 19, 2016
    Assignee: GENOVOXX GMBH
    Inventors: Claus Becker, Dmitry Cherkasov
  • Macromolecular nucleotide compounds and methods for using the same
    Patent number: 9035035
    Abstract: The invention describes new structures of the nucleotide conjugates (nuc-macromolecules) comprising at lease one nucleotide moiety coupled to at least one macromolecular compound via a short linker. These conjugates can be used as substrates for various kinds of polymerizing enzymes in the enzymatic synthesis of nucleic acids. In particular, these compounds can be used for labeling nucleic acids.
    Type: Grant
    Filed: March 17, 2006
    Date of Patent: May 19, 2015
    Assignee: GENOVOXX GMBH
    Inventors: Dmitry Cherkasov, Englbert Bäuml
  • NUCLEOSIDE-TRIPHOSPHATE CONJUGATE AND METHODS FOR THE USE THEREOF
    Publication number: 20150086981
    Abstract: The invention relates to a novel method for the enzymatic marking of nucleic acid chains (target sequences) with nucleotide conjugates. Under reaction conditions, said nucleotide conjugates are able to bind to a target sequence, and can be incorporated into the complementary growing strand by way of a polymerase. The nucleotide conjugates can be used for sequencing nucleic acid chains.
    Type: Application
    Filed: May 4, 2012
    Publication date: March 26, 2015
    Applicant: GENOVOXX GMBH
    Inventors: Dmitry Cherkasov, Claus Becker, Norbert Basler, Andreas Müller-Hermann, Petra Van Husen
  • METHOD AND COMPONENTS FOR DETECTING NUCLEIC ACID CHAINS
    Publication number: 20140295438
    Abstract: The invention relates to a novel method for the enzymatic marking of nucleic acid chains (target sequences) by means of nucleotide conjugates. Said nucleotide conjugates are able, under reaction conditions, to specifically bind to the target sequence and integrate into the complementary growing strand by means of a polymerase. The nucleic acid chains marked by such conjugates can be bound to the solid phase. The marking can be carried out parallel to the enzymatic amplification of target sequences.
    Type: Application
    Filed: April 26, 2012
    Publication date: October 2, 2014
    Applicant: GENOVOXX GMBH
    Inventors: Dmitry Cherkasov, Claus Becker, Norbert Basler, Andreas Muller-Hermann, Petra Van Husen
  • Macromolecular nucleotide compounds and methods for using the same
    Patent number: 8637650
    Abstract: The invention relates to novel classes of nucleotides that can be used as substrates for enzymes, e.g. for labeling nucleic acids.
    Type: Grant
    Filed: November 5, 2004
    Date of Patent: January 28, 2014
    Assignee: Genovoxx GmbH
    Inventors: Dmitry Cherkasov, Christian Hennig