Patents Assigned to Genpoint AS
  • Method for Detecting the Presence or Absence of a Target Cell in a Sample
    Publication number: 20090186346
    Abstract: The present invention relates to a method for detecting the presence or absence of a target cell in a sample, said method comprising (a) binding cells in said sample to a particulate and mixable solid support; (b) eluting the cells from the solid support without the use of competitor molecules to disrupt the interaction between the cell and the solid support; (c) after lysis of said cells, detecting the presence or absence of nucleic acid characteristic of said target cell, wherein said solid support does not have antibodies or antibody fragments immobilised thereon. Kits for carrying out the method of the invention are also provided.
    Type: Application
    Filed: December 12, 2006
    Publication date: July 23, 2009
    Applicant: GENPOINT AS
    Inventor: Marc Angles D'Auriac
  • Solid-phase nucleic acid isolation
    Patent number: 7560228
    Abstract: The present invention provides a method of isolating nucleic acid from a sample of cells, said method comprising: (a) binding cells in said sample in a solid support to isolate cells from the sample; (b) lysing the isolated cells; and (c) binding nucleic acid released from said lysed cells to said same solid support and a kit for carrying out such a method. The method may advantageously be used to prepare nucleic acid for use in a nucleic acid-based target cell detection method.
    Type: Grant
    Filed: June 11, 2003
    Date of Patent: July 14, 2009
    Assignee: Genpoint A/S
    Inventors: Knut Rudi, Kjetill Sigurd Jakobsen
  • Nucleic acid detection method
    Patent number: 6617138
    Abstract: A method of detecting a target nucleotide sequence in a nucleic acid molecule, which comprises: (a) binding of an oligonucleotide probe to said nucleic acid molecule; (b) selective labelling of the bound oligonucleotide probe in the presence of said target nucleotide sequence; (c) hybridization of the labelled oligonucleotide to a complementary sequence; and (d) subsequent detection of the label; such methods being suitable for qualitative and quantitative assays of microbiological populations.
    Type: Grant
    Filed: February 2, 2001
    Date of Patent: September 9, 2003
    Assignee: Genpoint AS
    Inventors: Knut Rudi, Kjetill Sigurd Jakobsen
  • Solid-phase nucleic acid isolation
    Patent number: 6617105
    Abstract: The present invention provides a method of isolating nucleic acid from a sample of cells, said method comprising: (a) binding cells in said sample to a solid support to isolate cells from the sample; (b) lysing the isolated cells; and (c) binding nucleic acid released from said lysed cells to said same solid support and a kit for carrying out such a method. The method may advantageously be used to prepare nucleic acid for use in a nucleic acid-based target cell detection method.
    Type: Grant
    Filed: February 7, 2000
    Date of Patent: September 9, 2003
    Assignee: Genpoint AS
    Inventors: Knut Rudi, Kjetill Sigurd Jakobsen