Patents Assigned to GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 4) LTD.
  • COMBINED INHIBITION OF PD-1, TGFB AND TIGIT FOR THE TREATMENT OF CANCER
    Publication number: 20230340122
    Abstract: The present invention relates to combination therapies useful for the treatment of cancer. In particular, the invention relates to the combined use of a PD-1 inhibitor, a TGF? inhibitor, and a TIGIT inhibitor to treat cancer.
    Type: Application
    Filed: November 5, 2020
    Publication date: October 26, 2023
    Applicants: GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 4) LTD., MERCK PATENT GmbH
    Inventors: Chunxiao XU, Feng JIANG, Dong ZHANG
  • IGG:TGFBETARII FUSION PROTEIN COMPOSITION
    Publication number: 20230043290
    Abstract: The present invention relates to a pharmaceutical composition, particularly a pharmaceutical composition comprising an IgG:TGF?RII (such as an anti-PD-L1:TGF?-inhibiting) fusion protein. The present invention also relates inter alia to a method of manufacturing the composition, to a kit including the composition, to a package including the composition, to a method of manufacturing the package, and to methods of treatment using the composition and/or package, especially cancer treatments.
    Type: Application
    Filed: December 21, 2020
    Publication date: February 9, 2023
    Applicants: ARES TRADING S.A., GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 4) LTD.
    Inventors: Chiara IORIO, Carlo PERGOLA, Fabiana CANAL, Gianluca RINALDI, Katrin GRIESER, Markus WEIGANDT, Matthias WINZER
  • COMBINED INHIBITION OF PD-1, TGFBeta AND ATM TOGETHER WITH RADIOTHERAPY FOR THE TREATMENT OF CANCER
    Publication number: 20230044248
    Abstract: The present invention relates to combination therapies useful for the treatment of cancer. In particular, the invention relates to the combined use of a PD-1 inhibitor, a TGF? inhibitor, an ATM inhibitor and radiation to treat cancer.
    Type: Application
    Filed: November 2, 2020
    Publication date: February 9, 2023
    Applicants: ARES TRADING S.A., GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 4) LTD.
    Inventors: Yan LAN, Adam S. LAZORCHAK