Patents Assigned to Gnothis Holding AG
  • Patent number: 11788140
    Abstract: The invention relates to a process for analysing single molecules, in particular for sequencing of single nucleic acid molecules.
    Type: Grant
    Filed: July 15, 2021
    Date of Patent: October 17, 2023
    Assignee: Gnothis Holding AG
    Inventors: Rudolf Rigler, Lars Edman
  • Publication number: 20230304087
    Abstract: The invention relates to a process and a device for analyzing single molecules, particularly to the parallel analysis of a plurality of single molecules. It is suitable for detecting interactions, e.g. binding between single molecules and/or reactions, e.g. elongation or degradation of single molecules. Particularly, the process of the invention relates to the sequencing of single nucleic acid molecules. The single molecule to be analyzed is present in free form, i.e. dissolved or suspended in a liquid medium, within a reaction space formed around the sample spot. According to the present invention, an electrical field is applied across the reaction space, whereby a concentration of single molecules, at the sample spots is effected.
    Type: Application
    Filed: November 2, 2022
    Publication date: September 28, 2023
    Applicant: GNOTHIS HOLDING AG
    Inventor: Rudolf RIGLER
  • Publication number: 20230295720
    Abstract: The invention relates to a process for analysing single molecules, in particular for sequencing of single nucleic acid molecules.
    Type: Application
    Filed: May 22, 2023
    Publication date: September 21, 2023
    Applicant: GNOTHIS HOLDING AG
    Inventors: Rudolf RIGLER, Lars EDMAN
  • Patent number: 11519030
    Abstract: The invention relates to a process and a device for analysing single molecules, particularly to the parallel analysis of a plurality of single molecules. It is suitable for detecting interactions, e.g. binding between single molecules and/or reactions, e.g. elongation or degradation of single molecules. Particularly, the process of the invention relates to the sequencing of single nucleic acid molecules. The single molecule to be analysed is present in free form, i.e. dissolved or suspended in a liquid medium, within a reaction space formed around the sample spot. According to the present invention, an electrical field is applied across the reaction space, whereby a concentration of single molecules, at the sample spots is effected.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: December 6, 2022
    Assignee: Gnothis Holding AG
    Inventor: Rudolf Rigler
  • Publication number: 20220002800
    Abstract: The invention relates to a process for analysing single molecules, in particular for sequencing of single nucleic acid molecules.
    Type: Application
    Filed: July 15, 2021
    Publication date: January 6, 2022
    Applicant: GNOTHIS HOLDING AG
    Inventors: Rudolf RIGLER, Lars EDMAN
  • Patent number: 11091805
    Abstract: The invention relates to a process for analysing single molecules, in particular for sequencing of single nucleic acid molecules.
    Type: Grant
    Filed: January 5, 2015
    Date of Patent: August 17, 2021
    Assignee: Gnothis Holding AG
    Inventors: Rudolf Rigler, Lars Edman
  • Publication number: 20160326581
    Abstract: The invention relates to a process for analysing single molecules, in particular for sequencing of single nucleic acid molecules.
    Type: Application
    Filed: January 5, 2015
    Publication date: November 10, 2016
    Applicant: GNOTHIS HOLDING AG
    Inventors: Rudolf RIGLER, Lars EDMAN
  • Publication number: 20060266136
    Abstract: The present invention relates to 5?-3?-bifluorophore-labelled probes for detecting analytes, in particular nucleic acids, in particular for confocal fluorescence spectroscopy.
    Type: Application
    Filed: June 8, 2004
    Publication date: November 30, 2006
    Applicant: Gnothis Holding AG
    Inventor: Holger Winter