Patents Assigned to GODX, INC
  • Rapid nucleic acids separation and sample preparation via hollow-centered silica microsphere
    Patent number: 11746372
    Abstract: Disclosed herein are method for separating, amplifying, or detecting a nucleic acid from a sample may comprise contacting a sample lysate with a plurality of buoyant, inorganic, nucleic-acid-capture microspheres. The nucleic-acid-capture microspheres may comprise unicellular hollow microspheres having a diameter between 5 and 300 ?m and/or a true particle density between 0.05 and 0.60 grams/cm3. The microspheres may comprise hollow soda-lime-borosilicate microspheres. In some embodiments, the microspheres comprises hollow soda-lime-borosilicate microspheres surrounded by an amorphous silica shell. Also disclosed are kits for performing the methods.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: September 5, 2023
    Assignees: GoDx, Inc., The United States of America, as Represented by the Secretary, Dep. of Health and Human Services
    Inventors: Chang Hee Kim, Lichen Xiang, Wendy A. Henderson, Xiao Jiang
  • RAPID NUCLEIC ACIDS SEPARATION AND SAMPLE PREPARATION VIA HOLLOW-CENTERED SILICA MICROSPHERE
    Publication number: 20210180108
    Abstract: Disclosed herein are method for separating, amplifying, or detecting a nucleic acid from a sample may comprise contacting a sample lysate with a plurality of buoyant, inorganic, nucleic-acid-capture microspheres. The nucleic-acid-capture microspheres may comprise unicellular hollow microspheres having a diameter between 5 and 300 ?m and/or a true particle density between 0.05 and 0.60 grams/cm3. The microspheres may comprise hollow soda-lime-borosilicate microspheres. In some embodiments, the microspheres comprises hollow soda-lime-borosilicate microspheres surrounded by an amorphous silica shell. Also disclosed are kits for performing the methods.
    Type: Application
    Filed: December 3, 2018
    Publication date: June 17, 2021
    Applicants: GoDx, Inc, The United States of America, as Represented by the Secretary, Department of Health and Human Servic
    Inventors: Chang Hee KIM, Lichen XIANG, Wendy A. HENDERSON, Xiao JIANG
  • POINT OF NEED TESTING DEVICE AND METHODS OF USE THEREOF
    Publication number: 20200354778
    Abstract: The present invention relates to the rapid and electricity-free, point-of-care, multiplexed detection and quantification of at least one or more nucleic acid sequences from nucleic acids corresponding to a plurality of pathogens or biomarkers using a micropatterned lateral flow device. Rapid and molecular-level sensitive differential diagnosis of a disease condition may be enabled without the need for a delayed laboratory test so that timely treatment can be administered.
    Type: Application
    Filed: July 28, 2020
    Publication date: November 12, 2020
    Applicants: GODX, INC, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES
    Inventors: Chang Hee Kim, Wendy A. Henderson, Sarah K. Abey, Nicolaas H. Fourie, Eric G. Ferguson
  • POINT OF NEED TESTING DEVICE AND METHODS OF USE THEREOF
    Publication number: 20180148774
    Abstract: The present invention relates to the rapid and electricity-free, point-of-care, multiplexed detection and quantification of at least one or more nucleic acid sequences from nucleic acids corresponding to a plurality of pathogens or biomarkers using a micropatterned lateral flow device. Rapid and molecular-level sensitive differential diagnosis of a disease condition may be enabled without the need for a delayed laboratory test so that timely treatment can be administered.
    Type: Application
    Filed: May 16, 2016
    Publication date: May 31, 2018
    Applicants: GODX, INC, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVIC
    Inventors: Chang Hee Kim, Wendy A. Henderson, Sarah K. Abey, Nicolaas H. Fourie, Eric G. Ferguson