Patents Assigned to Golden Biotechnology Corporation
  • Methods and compositions for treating advanced stage non-small cell lung cancer
    Patent number: 11786485
    Abstract: The present invention provides methods and compositions for treating advanced stage non-small cell lung cancer by cyclohexenone compounds.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: October 17, 2023
    Assignee: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Chih-Ming Chen, Pei-Ni Chen, Hao-Yu Cheng
  • Therapeutic compositions for treating pancreatic cancer
    Patent number: 11406605
    Abstract: The present invention is directed to therapeutic compositions for treating pancreatic cancer comprising a cyclohexnone compound and one or more anti-cancer agents.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: August 9, 2022
    Assignee: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Chih-Ming Chen
  • Methods and compositions for treating atopic dermatitis
    Patent number: 11364209
    Abstract: The present invention provides methods and compositions for treating atopic dermatitis by cyclohexenone compounds.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: June 21, 2022
    Assignee: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Chih-Ming Chen
  • Method for the treatment of fatty liver disease
    Patent number: 10959963
    Abstract: The invention provides a method of treating, inhibiting and/or preventing fatty liver disease in a patient in need thereof, comprising administering an effective amount of a cyclohexenone compound of the following formula (I) to said patient,
    Type: Grant
    Filed: November 29, 2019
    Date of Patent: March 30, 2021
    Assignee: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen
  • Methods and compositions for treating arteriosclerotic vascular diseases
    Patent number: 10905656
    Abstract: The present invention provides methods and compositions for treating arteriosclerotic vascular diseases by cyclohexenone compounds. In some embodiments, the compound in the methods inhibits PDGF-stimulated smooth muscle cell proliferation or migration. In some embodiments, the atherosclerosis is associated with coronary artery disease, aneurysm, arteriosclerosis, myocardial infarction, embolism, stroke, thrombosis, angina, vascular plaque inflammation, vascular plaque rupture, Kawasaki disease, calcification or inflammation. In some embodiments, the compound lowers low-density lipoprotein (LDL) cholesterol in the subject. In some embodiments, the compound maintains a normal low-density lipoprotein (LDL) cholesterol level in the subject.
    Type: Grant
    Filed: March 26, 2013
    Date of Patent: February 2, 2021
    Assignee: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen
  • Compositions and methods for treating liver cancer
    Patent number: 10858307
    Abstract: Provided herein are compositions and methods of treating liver cancer by novel anticancer agents.
    Type: Grant
    Filed: February 16, 2017
    Date of Patent: December 8, 2020
    Assignee: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Chih-Ming Chen
  • Methods and compositions for treating kidney disorders
    Patent number: 10406120
    Abstract: The present invention provides methods for treating glomerulosclerosis such as focal segmental glomerulosclerosis (FSGS) or glomerulonephritis such as immunoglobulin A nephropathy (IgAN) by cyclohexenone compounds.
    Type: Grant
    Filed: March 2, 2016
    Date of Patent: September 10, 2019
    Assignee: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, San-Bao Hwang
  • METHODS AND COMPOSITIONS FOR TREATING ADVANCED STAGE NON-SMALL CELL LUNG CANCER
    Publication number: 20190209492
    Abstract: The present invention provides methods and compositions for treating advanced stage non-small cell lung cancer by cyclohexenone compounds.
    Type: Application
    Filed: May 12, 2017
    Publication date: July 11, 2019
    Applicant: Golden Biotechnology Corporation
    Inventors: Sheng-Yung LIU, Chih-Ming CHEN, Pei-Ni CHEN, Hao-Yu CHENG
  • Methods and compositions for treating neurodegenerative diseases
    Patent number: 9861592
    Abstract: The present invention provides methods and compositions for treating neurodegenerative diseases by cyclohexenone compounds.
    Type: Grant
    Filed: November 21, 2013
    Date of Patent: January 9, 2018
    Assignee: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen
  • Methods and compositions for treating leukemia
    Patent number: 9403747
    Abstract: The present invention provides methods and compositions for treating leukemia by cyclohexenone compounds.
    Type: Grant
    Filed: February 20, 2014
    Date of Patent: August 2, 2016
    Assignee: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen
  • Cyclohexenone compositions and process for making thereof
    Patent number: 9365481
    Abstract: Provided herein are processes of preparing cyclohexenone compounds useful for cancer treatments and/or diseases.
    Type: Grant
    Filed: February 20, 2014
    Date of Patent: June 14, 2016
    Assignee: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen, Hsiu-Yi Cheng
  • Methods and Compositions for Treating Leukemia
    Publication number: 20150025135
    Abstract: The present invention provides methods and compositions for treating leukemia by cyclohexenone compounds.
    Type: Application
    Filed: February 20, 2014
    Publication date: January 22, 2015
    Applicant: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen
  • THERAPEUTIC METHODS AND COMPOSITIONS UTILIZING CYCLOHEXENONE COMPOUNDS
    Publication number: 20150018296
    Abstract: The present invention is directed to therapeutic methods and compositions involving cyclohexenone compounds where said compounds inhibit farnesyltransferase or Ras. The therapeutic methods (e.g. for treating cancers) comprise contacting a tumor with a cyclohexenone compound and an anticancer agent.
    Type: Application
    Filed: March 13, 2014
    Publication date: January 15, 2015
    Applicant: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen
  • Cyclohexenone Compositions and Process for Making Thereof
    Publication number: 20150018567
    Abstract: Provided herein are processes of preparing cyclohexenone compounds useful for cancer treatments and/or diseases.
    Type: Application
    Filed: February 20, 2014
    Publication date: January 15, 2015
    Applicant: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen, Hsiu-Yi Cheng
  • Inhibition of the Survival of Bladder Cancer by Cyclohexenone Compounds from Antrodia Camphorata
    Publication number: 20140179800
    Abstract: The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of Antrodia camphorata, which can be applied for inhibiting the survival of bladder cancer cells and be used as a pharmaceutical composition to inhibit the bladder tumor growth.
    Type: Application
    Filed: February 28, 2014
    Publication date: June 26, 2014
    Applicant: Golden Biotechnology Corporation
    Inventors: Sheng-Yun Liu, Wu-Che Wen, Mao-Tien Kuo
  • Inhibition of the Survival of Lymphoma by Cyclohexenone Compounds from Antrodia Camphorata
    Publication number: 20140179801
    Abstract: The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3 -dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6, 10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of Antrodia camphorata, which can be applied for inhibiting the survival of lymphoma cells and be used as a pharmaceutical composition to inhibit the lymphoma tumor growth.
    Type: Application
    Filed: March 3, 2014
    Publication date: June 26, 2014
    Applicant: Golden Biotechnology Corporation
    Inventors: Sheng-Yun Liu, Wu-Che Wen, Mao-Tien Kuo
  • METHODS AND COMPOSITIONS FOR TREATING NEURODEGENERATIVE DISEASES
    Publication number: 20140142194
    Abstract: The present invention provides methods and compositions for treating neurodegenerative diseases by cyclohexenone compounds.
    Type: Application
    Filed: November 21, 2013
    Publication date: May 22, 2014
    Applicant: Golden Biotechnology Corporation
    Inventors: Sheng-Yung LIU, Wu-Che WEN, Chih-Ming CHEN
  • Methods and compositions for treating cancer metastasis
    Patent number: 8648117
    Abstract: The present invention provides methods and compositions for treating cancer metastasis by cyclohexenone compounds.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: February 11, 2014
    Assignee: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Wu-Che Wen
  • METHODS AND COMPOSITIONS FOR TREATING CANCER METASTASIS
    Publication number: 20130225691
    Abstract: The present invention provides methods and compositions for treating cancer metastasis by cyclohexenone compounds.
    Type: Application
    Filed: February 22, 2013
    Publication date: August 29, 2013
    Applicant: Golden Biotechnology Corporation
    Inventor: Golden Biotechnology Corporation
  • METHODS AND COMPOSITIONS FOR TREATING OVARIAN CANCER
    Publication number: 20130203861
    Abstract: The present invention provides methods and compositions for treating ovarian cancer by cyclohexenone compounds.
    Type: Application
    Filed: March 14, 2013
    Publication date: August 8, 2013
    Applicant: GOLDEN BIOTECHNOLOGY CORPORATION
    Inventor: Golden Biotechnology Corporation