Patents Assigned to Government of India
  • Patent number: 11738036
    Abstract: The present invention includes Uttroside B compositions and method for the treatment of hepatocellular carcinoma. Chemotherapeutic options for liver cancer are limited and the prognosis of HCC patients remains dismal. Sorafenib, is the only drug currently available for the treatment of hepatocellular carcinoma.
    Type: Grant
    Filed: May 27, 2017
    Date of Patent: August 29, 2023
    Assignee: RAJIV GANDHI CENTRE FOR BIOTECHNOLOGY, AN AUTONOMOUS INSTITUTE UNDER THE DEPARTMENT OF BIOTECHNOLOGY, GOVERNMENT OF INDIA
    Inventors: Ruby John Anto, Lekshmi Reghu Nath
  • Publication number: 20230230717
    Abstract: The present invention discloses a method for the separation of radionuclides from an aqueous radioactive waste solution, the method comprising: receiving of an aqueous radioactive waste solution, adding at least one zirconium salt to the aqueous radioactive waste solution, changing the pH of the radioactive waste solution to obtain a precipitate P, and separating the precipitate P from the radioactive waste solution. The present invention also discloses the use of zirconium salts, preferably zirconium oxychloride, zirconium nitrate or a zirconium oxynitrate or any mixture thereof, for the treatment of aqueous radioactive waste solution, preferably acidic or alkaline intermediate or low level radioactive waste solution, preferably an acidic intermediate and/or low level radioactive waste solution.
    Type: Application
    Filed: January 14, 2022
    Publication date: July 20, 2023
    Applicant: Department of Atomic Energy Government of India
    Inventors: Sumit Pahan, Arvind Ananthanarayanan, Raman Kumar Mishra, Dayamoy Banerjee, Tessy Vincent, Sugilal Gopalakrishnan, Chetan Parkash Kaushik
  • Patent number: 11607422
    Abstract: The present invention includes Uttroside B compositions and method for the treatment of hepatocellular carcinoma. Chemotherapeutic options for liver cancer are limited and the prognosis of HCC patients remains dismal. Sorafenib, is the only drug currently available for the treatment of hepatocellular carcinoma.
    Type: Grant
    Filed: January 29, 2021
    Date of Patent: March 21, 2023
    Assignee: RAJIV GANDHI CENTRE FOR BIOTECHNOLOGY, AN AUTONOMOUS INSTITUTE UNDER THE DEPARTMENT OF BIOTECHNOLOGY. GOVERNMENT OF INDIA
    Inventors: Ruby John Anto, Lekshmi Reghu Nath
  • Patent number: 10101467
    Abstract: This invention relates to a sensor device consisting of long period gratings made of rare-earth doped double clad fiber, which is written by CO2 laser irradiation while the fiber is held static, for gamma dose measurement in the range of 150 Gy-2.5 kGy, extendable to 20 kGy, which measurements are real-time and can be from remote locations. The sensor device has high wavelength dip shift sensitivity of at least 2.8 nm/kGy, and its radiation-induced changes are near permanent. The gratings demonstrate negligible temperature sensitivity and the shifts recorded show negligible annealing at room temperature.
    Type: Grant
    Filed: August 11, 2016
    Date of Patent: October 16, 2018
    Assignee: SECRETARY, DEPARTMENT OF ATOMIC ENERGY, GOVERNMENT OF INDIA
    Inventors: Sanjay Kher, Smita Chaubey, Jai Kishore, Srikant M. Oak
  • Patent number: 9975866
    Abstract: In accordance with the present subject matter, there is provided a process for preparing a furan derivative, the process comprising the steps of contacting a sugar with a monophasic organic solvent to obtain a reaction mixture; and subjecting the reaction mixture to a temperature in the range from 100° C. to 180° C., in presence of an acid catalyst, for a time period in the range of 0.5 min to 4.0 h to obtain at least 70% conversion of the sugar to a single furan derivative, wherein the acid catalyst is selected from the group consisting of homogenous acid catalyst, heterogenous solid acid catalyst, and combinations thereof. There is also provided a process for preparation of a heterogenous solid acid catalyst.
    Type: Grant
    Filed: November 21, 2014
    Date of Patent: May 22, 2018
    Assignees: DEPARTMENT OF BIOTECHNOLOGY. MINISTRY OF SCIENCE AND TECHNOLOGY, GOVERNMENT OF INDIA, INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Arvind Mallinath Lali, Hitesh Suresh Pawar
  • Patent number: 9174855
    Abstract: An improved process for the preparation of high purity rare metal compounds such as oxides utilizing TBP (Tri-Butyl Phosphate)-nitrate solvent extraction technique adapted to manufacture nuclear grade rare metal compounds such as zirconium oxide wherein the said process substantially aids in reducing the specific generation of ammonium nitrate effluent volume thereby increasing its concentration when the said effluent comprising ammonium nitrate and ammonium sulphate are utilized for stripping of the said rare metal compound from the organic solvent in the said process of production of high purity rare metal oxide powder.
    Type: Grant
    Filed: October 1, 2010
    Date of Patent: November 3, 2015
    Assignee: The Secretary, Department of Atomic Energy, Government of India
    Inventors: Kumar Chandru Asnani, Venkata Siva Rama Ravi Kanth Mukku, Prakash Buddha, Jayaraj Raigiri
  • Patent number: 8840594
    Abstract: A collector for fecal discharge is provided comprising a self-expanding resilient collection component, a housing sheath and a transit component. The collection component has an open proximal and distal end and a lumen connecting them. The component comprises interconnected resilient arms circumscribing its contour, wherein adjacent arms are resiliently biased away from each other for exerting outwardly radial pressure for expanding and anchoring the component to rectal walls upon deployment. The housing sheath comprises a flexible and resilient material overlaying at least one of inner or outer contour of collection component without interfering with or blocking its ends or lumen. The transit component provides a conduit for fecal discharge to migrate from collection component to a receptacle and comprises a flexible, tubular sheath having a first open end connected to a second end by a lumen, wherein the first end engages with the proximal end of the collection component.
    Type: Grant
    Filed: June 16, 2010
    Date of Patent: September 23, 2014
    Assignee: Department of Biotechnology, Ministry of Science and Technology, Government of India
    Inventors: Amit K. Sharma, Nishith Chasmawala, Sandeep Singh
  • Patent number: 8524770
    Abstract: The present invention relates to a wool care composition comprising pyrethroid insecticide, a copolymer and a solvent wherein the said copolymer binds with the solvent and pyrethroid insecticide. This composition can be an improved aerosol spray formulation for treating of pure or blended woollen clothing and textile, fur and feather lined garments and other keratinous items for protection or insect proofing from various types of insect pests both clothes moths and carpet beetles during their storage, transport and use. Wool care aerosol solution can be sprayed with pressurized container having either a propellant as ready-to-use aerosol or manually operated sprayers. The aerosol spray composition may also contain fragrance and solvent. The other components in the composition are at least one copolymer/emulsifier and/or dispersant.
    Type: Grant
    Filed: November 20, 2009
    Date of Patent: September 3, 2013
    Assignee: Director General, Defence Research & Development Organization, Ministry of Defence, Government of India
    Inventors: Veer Vijay, Prakash Shri, Chandel Kshitij, Jaywantrao Mendki Murlidhar, Vijayaraghavan Rajagopalan, Krishnamurthy Sekhar
  • Patent number: 8097826
    Abstract: A Penetration Enhancing Activating Flux (PEAF) in paste form for autogenous TIG welding of austenitic stainless steels adapted for ready application with a brush on top weld surface prior to conducting autogenous TIG welding to favor single weld pass, of austenitic stainless steels of AISI 304LN and AISI 316LN varieties with weld bead penetration up to a section thickness of 12 mm. Importantly, the (PEAF) paste based TIG welding of the invention achieves an increase in weld bead penetration of about 300% over the conventional TIG process without activating flux. The PEAF paste based TIG welding also favors higher productivity and high quality apart from being cost-effective due to less requirement of consumables and controlled heat input to arrest distortion, making it widely acceptable for variety of industrial applications for welding of austenitic stainless steel.
    Type: Grant
    Filed: November 8, 2006
    Date of Patent: January 17, 2012
    Assignee: The Secretary, Department of Atomic Energy, Government of India
    Inventors: Vasudevan Muthukumaran, Arun Kumar Bhaduri, Baldev Raj
  • Patent number: 7691171
    Abstract: This invention provides a process for the preparation of water insoluble, bio-release iron-manganese fertilizer which comprises, heating phosphoric acid with a mixture of (i) source of iron oxide such as goethite and hematite, (ii) pyrolusite and (iii) one or more basic compound(s) selected from oxide(s) or carbonate(s) of magnesium, calcium, sodium and potassium, (b) neutralisation followed by drying and pulverisation.
    Type: Grant
    Filed: August 6, 2004
    Date of Patent: April 6, 2010
    Assignee: Department of Science & Technology (DST) A Department under the Ministry of Science and Technology, Government of India
    Inventor: Chandrika Varadachari
  • Publication number: 20100068559
    Abstract: A Penetration Enhancing Activating Flux (PEAF) in paste form for autogenous TIG welding of austenitic stainless steels adapted for ready application with a brush on top weld surface prior to conducting autogenous TIG welding to favour single weld pass, of austenitic stainless steels of AISI 304LN and AISI 316LN varieties with weld bead penetration up to a section thickness of 12 mm. Importantly, the above (PEAF) paste based TIG welding of the invention achieves an increase in weld bead penetration of about 300% over the conventional TIG process without activating flux. The PEAF paste based TIG welding also favours higher productivity and high quality apart from being cost-effective due to less requirement of consumables and controlled heat input to arrest distortion, making it widely acceptable for variety of industrial applications for welding of austenitic stainless steel.
    Type: Application
    Filed: November 8, 2006
    Publication date: March 18, 2010
    Applicant: The Secretary, Department of Atomic Energy, Government of India
    Inventors: Vasudevan Muthukumaran, Arun Kumar Bhaduri, Baldev Raj
  • Patent number: 7575877
    Abstract: The present invention relates to a method of diagnosing tuberculosis in a subject, said method comprising steps of: detecting anti-Mycobacterium tuberculosis (M.tb.) isocitrate dehydrogenase (ICDs) antibody in the subject, and diagnosing tuberculosis in the subject.
    Type: Grant
    Filed: July 20, 2005
    Date of Patent: August 18, 2009
    Assignee: Centre for DNA Fingerprinting and Diagnostics, Department of Biotechnology, Ministry of Science & Technology, Government of India. Nacharam.
    Inventors: Seyed Ehtesham Hasnain, Sharmistha Banerjee, Ashok Nandyala, Raviprasad Podili, Vishaw M Katoch, Kolluri Janaki Rama Murthy
  • Patent number: 7502107
    Abstract: A system and the method for transport of microscopic objects/particles involving the use of laser source operatively connected to a microscope objective which is adapted to generate optical focal spots on said particle(s) with asymmetric intensity profile in transverse plane followed by varying the said asymmetry of the gradient optical forces on the micron sized object/particles to thereby transport the microscopic object(s). The system and the method can be used to transport microscopic objects including i) transportation of cells and intra-cellular organelles, ii) acceleration of microscopic objects along any direction in a plane transverse to the direction of propagation of laser beam, iii) optical channeling of objects through a micro-capillary from one micro-well to another and transfer to another channel after desired processing, iv) sorting of microscopic objects, v) optical control of micro-machines, micro-fluidic devices etc.
    Type: Grant
    Filed: August 22, 2003
    Date of Patent: March 10, 2009
    Assignee: Secretary, Department Of Atomic Energy, Government of India
    Inventors: Samarendra Kumar Mohanty, Pradeep Kumar Gupta
  • Publication number: 20080145448
    Abstract: A new prophylactic mixture is prepared for the effective decorporation of *Cs, *Sr, *I from affected subjects in the event of an accidental release of the radioisotopes in the environment due to any nuclear accident. The prophylactic mixture comprising: 1) Calcium Potassium Ferrocyanide [CaK2Fe(CN)6] 2) Calcium Iodate, and 3) Calcium Carbonate, can be formulated in the form of a single tablet, capsule or suspension for easy administration to the radiation affected subjects in cases of emergency or nuclear fallout. Also claimed are the compound calcium potassium ferrocyanide (CaK2Fe(CN) 6) and the use thereof for decorporation of *Cs in subjects affected by nuclear radiation.
    Type: Application
    Filed: January 10, 2006
    Publication date: June 19, 2008
    Applicant: SECRETARY, DEPARTMENT OF ATOMIC ENERGY GOVERNMENT OF INDIA
    Inventors: Dharampal Nandiram Pahuja, Vikram Sarjerao Jagtap, Vinay Ramkrishna Sonawane
  • Patent number: 7312028
    Abstract: A simple easy to manufacture analytical device capable of performing membrane based immunoassays on batch of samples within 3 to 10 minutes wherein the method permits focused application of samples, costly labeled immunoassay and signal amplification reagents, said device includes an antibody-immobilized micro porous membrane, breadth corner layer of which is directly attached to a semi-rigid liquid-impervious body with water insoluble adhesive; absorbent body is provided separately and is not attached to analytical device during manufacture, absorbent body is wetted and is placed proximal to the lower surface of the membrane thereby forming networks of capillary channels with the absorbent body; flow of samples or reagents is always kept downwards and focused without application of any force to the absorbent body and the use of disposable adsorbent body permits stepwise addition of signal amplification reagents for ultra sensitive detection of diagnostically important molecules by visual examination of the m
    Type: Grant
    Filed: July 28, 2006
    Date of Patent: December 25, 2007
    Assignees: Council of Scientific & Industrial Research, Department of Biotechnology, A Department of Government of India
    Inventors: Tarun K. Dhar, Arindam Pal
  • Patent number: 7238359
    Abstract: The present invention relates to a PPE family antigenic protein Rv2430c of SEQ ID No. 1; a set of three high antigenic index peptides of SEQ ID Nos. 2 to 4; an antigenic ORF Rv2430c of SEQ ID No. 5 and lastly a method of inducing immune response against Mycobacterium tuberculosis in a subject in need thereof, said method comprising step of: introducing PPE antigenic protein Rv2430c of SEQ ID No. 1 into the subject and inducing immune response against Mycobacterium tuberculosis.
    Type: Grant
    Filed: August 9, 2005
    Date of Patent: July 3, 2007
    Assignees: An Autonomous Centre for the Department of Biotechnology, Ministry of Science & Technology, Government of India
    Inventors: Seyed Ehtesham Hasnain, Rakesh Kumar Choudhary
  • Patent number: 7192563
    Abstract: A two-cycle countercurrent extraction process for recovery of highly pure uranium from fertilizer grade weak phosphoric acid. The proposed process uses selective extraction using di-(2-ethyl hexyl) phosphoric acid (D2EHPA) and tri-n-butyl phosphate (TBP) with refined kerosene as synergistic extractant system on hydrogen peroxide treated phosphoric acid, and stripping the loaded extract with strong phosphoric acid containing metallic iron to lower redox potential. The loaded-stripped acid is diluted with water back to weak phosphoric acid state and its redox potential raised by adding hydrogen peroxide and re-extracted with same extractant system. This extract is first scrubbed with sulfuric acid and then stripped with alkali carbonate separating iron as a precipitate, treated with sodium hydroxide precipitating sodium uranate, which is re-dissolved in sulfuric acid and converted with hydrogen peroxide to highly pure yellow cake of uranium peroxide.
    Type: Grant
    Filed: March 31, 2002
    Date of Patent: March 20, 2007
    Assignee: Secretary, Department of Atomic Energy, Government of India
    Inventors: Harvinderpal Singh, Shyamkant Laxmidutt Mishra, Anitha Mallavarapu, Vijayalakshmi Ravishankar, Ashok Baswanthappa Giriyalkar, Manojkumar Kedarnath Kotekar, Tapan Kumar Mukherjee
  • Patent number: 7129211
    Abstract: The present invention relates to an adipocyte Insulin adpInsl with Insulin A and B chains of SEQ ID Nos. 1 and 2, a effective method of treating type 2 diabetes in a subject using adipocyte insulin, said method comprising steps of administering the insulin to a diabetic intraperitoneally, an Insulin gene of SEQ ID No. 3, a process of isolating protein Insulin from the adipocytes of the Carp, said method comprising steps of reverse transcripting RNA of adipocytes to obtain cDNA, using oligonucleotide primers of SEQ ID Nos. 5 and 6 to identify AdpInsl gene from cDNA, and deducing amino acid sequence from cDNA to obtain protein Insulin, and an adipocyte of Catla Catla useful for producing the said Insulin.
    Type: Grant
    Filed: March 26, 2003
    Date of Patent: October 31, 2006
    Assignees: Council of Scientific and Industrial Research, Department of Biotechnology Department of the Government of India
    Inventors: Samir Bhattacharya, Sib Sankar Roy, Subrata Dasgupta, Mohua Mukherjee
  • Patent number: 7009182
    Abstract: The invention relates to a pocket type digital radiation dosemeter comprising of a detector, which converts the ionisation in the detector caused by the incidence of ionising radiation of certain energy range into electrical impulses, a low power pulse amplifier, that amplifies the electrical pulses from the detector to detectable amplitudes, a discriminator circuit, that is used to reject pulses of origin other than those caused by the ionising radiation, a programmable divider circuit for calibrating the dosemeter, an electronic counting circuit and a six digit LCD display. The sensitivity of the dosemeter is 1 count per ?Sv (micro Sievert) and the accuracy is within ±15% from 60 keV to 1.25 Mev of X or Gamma radiation. A metallic energy compensation filter and a discriminator threshold modulation circuit are used to provide uniform response within ±15% from 60 KeV to 1.25 MeV.
    Type: Grant
    Filed: September 7, 2001
    Date of Patent: March 7, 2006
    Assignee: Department of Atomic Energy, Government of India
    Inventors: Subramaniam Kannan, Keshav Chander Bajaj, Madhuri Dilip Lalsare
  • Patent number: D755501
    Type: Grant
    Filed: January 26, 2014
    Date of Patent: May 10, 2016
    Assignee: Defence Research Development Organization Ministry of Defense, Government of India
    Inventors: Satish Ramdas Nayak, Reny Mammen Roy, Rabindra Kumar Sinha, Shri Nandan Asthana, Bikash Bhattacharya