Abstract: The present invention relates to oxygen barrier film structures and a method of using thereof. More particularly, the invention relates to oxygen barrier film structures comprising at least one substrate, a primer layer on at least one surface of the substrate, said primer comprising a mixture of at least one aqueous dispersion of polyurethane (A) and at least one water dispersible crosslinking agent (B); an oxygen and moisture resistant barrier coating onto said primer treated surface of the polymeric substrate; said coating comprising a mixture of at least one aqueous polyvinyl alcohol or its copolymers (C) and at least one crosslinking agent (D). Improved adhesion properties of the barrier coating on substrates such as polyolefin, polyester and polyamide are obtained.