Patents Assigned to Hamilton-Thorn Research
  • Patent number: 5306467
    Abstract: A magnetic slide loading is used with automated cell counting equipment or manual optical microscopes to measure the number of cells in a fluid biological sample. A slide having a defined volume region holds the sample for measurement. A cover slip is placed over the defined volume region creating an enclosed volume. An actuable holder clamp is placed over the slide securing it as well as the cover slip in position by virtue of magnets secured to the bottom of the device exerting a magnetic force upon the holder clamp such that it is attracted toward the slide forcing the cover slip to flatten, thereby removing any defects or distortions from the volume. This action ensures that the volume has a uniform depth allowing accurate measurement of cell concentration within the biological sample.
    Type: Grant
    Filed: February 17, 1993
    Date of Patent: April 26, 1994
    Assignee: Hamilton-Thorn Research
    Inventors: Diarmaid H. Douglas-Hamilton, Thomas Kenny
  • Patent number: 4896967
    Abstract: An improved motility scanner is disclosed for characterizing the motion of sperm, bacteria, particles suspended in flowing fluids and the like. The motility scanner includes an improved optical system, a source of illumination for the system and radiation sensing means including electronic image reversal means coupled to the system. A disposable specimen holder allows external loading thereof and its positioning on a heated specimen support. The illumination source functions as a collimator in directing all of the emanating illumination onto the specimen. Both directly transmitted light and light scattered by the specimen are received by an imaging lens and are both focussed thereby onto pixels of a light sensitive device. A movable plate provided with a retarding member is designed to be located at the plane conjugate to the plane of the small source aperature. The directly transmitted light is transmitted through the retarding member and/or the attenuating member.
    Type: Grant
    Filed: March 11, 1988
    Date of Patent: January 30, 1990
    Assignee: Hamilton-Thorn Research
    Inventors: Diarmaid H. Douglas-Hamilton, Paul Boisseau
  • Patent number: 4896966
    Abstract: A motility scanner and method are disclosed for characterizing the motion of sperm, bacteria, particles suspended in flowing fluids and the like. The motility scanner preferably is mounted as a portable unit in a container and includes an optical system, a source of illumination for the system, a heated specimen support disposed in the system, ratiation sensing means coupled to the system, signal processing means for analyzing signals generated by the radiation sensing means, and a front panel disposed on the container and featuring an output screen, a printer and controls required for operating the motility detector, including a power switch. A disposable specimen holder of unique design allows external loading thereof and its positioning on the heated specimen support. The source of illumination can be a conventional filament lamp or one or more LED's. Power for the motility scanner can be self contained by incorporating a battery pack within the container or it can be derived from a conventional 110 V.A.C.
    Type: Grant
    Filed: August 15, 1986
    Date of Patent: January 30, 1990
    Assignee: Hamilton-Thorn Research
    Inventors: Paul Boisseau, Diarmaid H. Douglas-Hamilton, Thomas P. Sosnowski
  • Patent number: 4690678
    Abstract: In an artificial vagina for use in animal artificial insemination that includes a tubular section with an intromission orifice, a thin, flexible plastic sheet liner of a generally cylindrical shape with an intromission opening and a collection chamber is insertable into the artificial vagina, and disposable after one use. A filter mounted on a ring is located within the liner at a reduced diameter portion located intermediate the collection chamber and the main portion of the liner. An external strap frictionally engages the ring to secure the filter.
    Type: Grant
    Filed: June 24, 1985
    Date of Patent: September 1, 1987
    Assignee: 501 Hamilton/Thorn Research Associates
    Inventor: Margaret M. Douglas-Hamilton