Patents Assigned to Hasumi International Research Foundation
  • Patent number: 9089593
    Abstract: The invention relates to a method of treating tumor cells within a patient wherein immature dendritic cells developed from the patient's monocyte cells and a lymphocyte cultured medium (LCM) adjuvant are introduced into the patient directly into the patient's tumor cells. The immature dendritic cells and LCM adjuvant combine with the antigens in the tumor cells to form a cancer vaccine, thereby immediately treating the tumor cells of the patient. The invention also provides a precursor treatment step of treating the patient with radiation therapy or a chemotherapy regimen.
    Type: Grant
    Filed: November 23, 2011
    Date of Patent: July 28, 2015
    Assignee: Hasumi International Research Foundation
    Inventor: Kenichiro Hasumi
  • Publication number: 20150079032
    Abstract: The invention relates to therapy and methods of applying the therapy to a patient. The invention includes the introduction of immature dendritic cells into the patient and the introduction of anti-TNF antibody into the patient. The immature dendritic cells are introduced intratumorally and/or through vessel and the anti-TNF antibody is introduced intratumorally and/or through vessel and/or subcutaneously. The immature dendritic cells can be formed by collecting monocyte cells from the patient and culturing the cells in a culture medium. The invention can be effective to regress, reduce or eliminate tumor cells in tumor tissue of the patients, including metastasized tumors. Further, the treatment of the invention is effective in the absence of conventional therapy, such as radiotherapy and chemotherapy.
    Type: Application
    Filed: November 21, 2014
    Publication date: March 19, 2015
    Applicant: HASUMI INTERNATIONAL RESEARCH FOUNDATION
    Inventor: KENICHIRO HASUMI
  • Patent number: 8961957
    Abstract: The invention relates to therapy and methods of applying the therapy to cancer patients. The invention includes introducing intratumorally cytotoxic T lymphocyte and/or NKT cells, and prior to, coincident with, or following introducing intratumorally the cytotoxic T lymphocyte and/or NKT cells, introducing intratumorally anti-TNF and/or anti-IL-10 to the patient. The cytotoxic T lymphocyte and/or NKT cells can be induced by the intratumoral introduction of immature dendritic cells to the patient. This therapy of the invention can be effective to regress, reduce or eliminate tumor cells in tumor tissue of the patients in the absence of radiation therapy.
    Type: Grant
    Filed: June 27, 2013
    Date of Patent: February 24, 2015
    Assignee: Hasumi International Research Foundation
    Inventor: Kenichiro Hasumi
  • Publication number: 20150023997
    Abstract: The invention relates to compositions, methods and therapies for the treatment of inflammation caused by infection with Propionibacterium acnes. The compositions include a combination of peptide and anti-TNF. The peptide consists of a specific amino acid sequence or a peptide consisting of an amino acid sequence derived the specific amino acid sequence by deletion, substitution, insertion or addition of one or more amino acids. The administration of the peptide and anti-TNF in therapeutically effective amounts to a patient is effective to suppress, by immune response, inflammation caused by infection with Propionibacterium acnes.
    Type: Application
    Filed: June 23, 2014
    Publication date: January 22, 2015
    Applicant: Hasumi International Research Foundation
    Inventors: KENICHIRO HASUMI, MIKIO KURAYA
  • Publication number: 20140004126
    Abstract: The invention relates to therapy and methods of applying the therapy to cancer patients. The invention includes introducing intratumorally cytotoxic T lymphocyte and/or NKT cells, and prior to, coincident with, or following introducing intratumorally the cytotoxic T lymphocyte and/or NKT cells, introducing intratumorally anti-TNF and/or anti-IL-10 to the patient. The cytotoxic T lymphocyte and/or NKT cells can be induced by the intratumoral introduction of immature dendritic cells to the patient This therapy of the invention can be effective to regress, reduce or eliminate tumor cells in tumor tissue of the patients in the absence of radiation therapy.
    Type: Application
    Filed: June 27, 2013
    Publication date: January 2, 2014
    Applicant: Hasumi International Research Foundation
    Inventor: KENICHIRO HASUMI
  • Publication number: 20120071860
    Abstract: The invention relates to a method of treating tumor cells within a patient wherein immature dendritic cells developed from the patient's monocyte cells and a lymphocyte cultured medium (LCM) adjuvant are introduced into the patient directly into the patient's tumor cells. The immature dendritic cells and LCM adjuvant combine with the antigens in the tumor cells to form a cancer vaccine, thereby immediately treating the tumor cells of the patient. The invention also provides a precursor treatment step of treating the patient with radiation therapy or a chemotherapy regimen.
    Type: Application
    Filed: November 23, 2011
    Publication date: March 22, 2012
    Applicant: HASUMI INTERNATIONAL RESEARCH FOUNDATION
    Inventor: KENICHIRO HASUMI
  • Patent number: 8076132
    Abstract: The invention relates to a method of treating tumor cells within a patient wherein immature dendritic cells developed from the patient's monocyte cells and a lymphocyte cultured medium (LCM) adjuvant are introduced into the patient directly into the patient's tumor cells. The immature dendritic cells and LCM adjuvant combine with the antigens in the tumor cells to form a cancer vaccine, thereby immediately treating the tumor cells of the patient. The invention also provides a precursor treatment step of treating the patient with radiation therapy or a chemotherapy regimen.
    Type: Grant
    Filed: April 10, 2008
    Date of Patent: December 13, 2011
    Assignee: Hasumi International Research Foundation
    Inventor: Kenichiro Hasumi