Patents Assigned to HEJ Research Institute
  • Anticancer Compound
    Publication number: 20130018025
    Abstract: Azadirachta indica cell suspension culture is used to metabolize dianabol to yield potent anticarcinogenic 17?-hydroxy-17?-methyl-5?-androst-1-en-3-one, which can also be synthesized.
    Type: Application
    Filed: July 17, 2011
    Publication date: January 17, 2013
    Applicant: HEJ Research Institute of Chemistry
    Inventors: Saifullah, Saifullah Khan, Azizuddin, Muhammad Kashif, Ahsana Dar, Muhammad Iqbal Choudhary
  • Tyrosinase enzyme inhibitors from fungal hydroxylation of tibolone
    Publication number: 20090136434
    Abstract: Seven new and one known metabolites of tibolone were obtained by incubation of tibolone with various fungi. Their structures were elucidated by means of a homo and heteronuclear 2D NMR and by HREI-MS techniques. The relative stereochemistry was deduced by 2D NOESY experiment. These metabolites of tibolone were strong inhibitors of tyrosine enzyme and thus useful in producing skin lightning and preserving fruits and vegetables.
    Type: Application
    Filed: November 23, 2007
    Publication date: May 28, 2009
    Applicant: HEJ Research Institute
    Inventors: Attaur Rahman, Muhammad Iqbal Choudhary, Syed Adnan Ali Shah, Mahmud Tareq Hassan Khan
  • Novel alpha glucosidase inhibitors from lichens
    Publication number: 20080318916
    Abstract: This invention is directed to a novel method for the inhibition of ?-glucosidase enzyme and thus treating diabetes, viral infections, fungal infections, autoimmune function disorders and obesity using compounds derived as lichen metabolites; more specifically, this includes the therapeutic applications of methylorsellinate (2,4-dihydroxy-6-methylbenzoate, Compound I), methyl-?-orinolcarboxylate (2,4-dihydroxy-3,6-dimethylbenzoate, Compound II) and zeorin (6,22-hopanediol, Compound III).
    Type: Application
    Filed: June 22, 2007
    Publication date: December 25, 2008
    Applicants: Department of Chemistry, University of Peradeniya, HEJ Research Institute
    Inventors: Vinitha Moolchand Thadani, Veranja Karunaratne, Muhammad Iqbal Choudhary
  • Novel alpha glucosidase activator, pulicarside 1
    Publication number: 20080274987
    Abstract: A new ent-kaurane type diterpene glucoside, pulicarside (1) was isolated from Pulicaria undulate with a strong ?-glucosidase promoter activity; a large number of clinical applications are provided.
    Type: Application
    Filed: June 7, 2006
    Publication date: November 6, 2008
    Applicant: HEJ Research Institute
    Inventors: Viqar Uddin Ahmad, Muhammad Iqal Choudhary, Nasir Khan, Shamsun Nihar Khan
  • Anticonvulsant compounds
    Patent number: 7399888
    Abstract: The invention relates to novel isoxylitones and their use as anticonvulsant and in the treatment of a variety of disorders.
    Type: Grant
    Filed: July 1, 2006
    Date of Patent: July 15, 2008
    Assignee: HEJ Research Institute Karachi University
    Inventors: Attaur Rahman, Mohammad Iqbal Choudhary, Farzana Shaheen, Arun Ganesan, Shabana Usman Simjee, A. Mohsin Raza
  • New Anticonvulsant Compounds
    Publication number: 20080004353
    Abstract: The invention relates to novel isoxylitones and their use as anticonvulsant and in the treatment of a variety of disorders
    Type: Application
    Filed: July 1, 2006
    Publication date: January 3, 2008
    Applicant: HEJ RESEARCH INSTITUTE OF CHEMISTRY
    Inventors: Attaur Rahman, Mohammad Iqbal Choudhary, Farzana Shaheen, A Ganesan, Shabana Usman Simjee, A Mohsin Raza
  • New treatment of diabetes mellitus
    Publication number: 20070287674
    Abstract: This invention is directed to a novel method for the treatment of diabetes mellitus (Type I, Impaired Glucose Tolerance [“IGT”] and Type II) by administering a therapeutically effective amount of one or both ?-glucosidase inhibitor namely paniculoside IV and ent-16, 17-dihydroxy-(?)-kauran-19-oic acid to humans and animals.
    Type: Application
    Filed: June 8, 2006
    Publication date: December 13, 2007
    Applicant: HEJ RESEARCH INSTITUTE OF CHEMISTRY
    Inventors: Viqar Uddin Ahmad, Nasir Rasool, Muhammad Iqbal Choudhary, Shamsun Nihar Khan