Abstract: A genomic update system can generate a user interface from network pages based on user variant data and network services associated with the network pages. A trait data structure tracks network services for different trait categories. A given network page of a given category can be used to identify a different category and different network services and content for display to a user. Content in the trait data structure can be included in a user interface with additional contextual visualizations that allow the user to interact with the links and content via a user device, such as a handheld mobile device.

Abstract: The present disclosure provides methods for determining collagen content using collagen hybridizing peptides. The present disclosure provides methods for quantifying an amount of disrupted collagen (e.g., collagen with disrupted triple helicity) and/or total collagen. The present disclosure provides methods for quantifying an amount of disrupted collagen (e.g., collagen with disrupted triple helicity) as a portion of total collagen.

Abstract: Systems and methods are provided for controlling dissemination of genomic data. One embodiment is a system that stores genomic data. The genomic data for each individual lists genetic variants determined to exist within that individual. The system receives an access request for a segment of genomic data for an individual, analyzes an authentication token within the request, authenticates the request as belonging to an account for a user based on the authentication token, and reviews authorization directives for the individual that indicate how predefined portions of genomic data are shared. The system also transmits the segment of genomic data in response to determining that the authorization directives permit the account to access the segment of genomic data, and prevents transmission of the segment of genomic data in response to determining that the authorization directives do not permit the account to access the segment of genomic data.

Abstract: Systems and methods are provided for quality control for biological testing. One embodiment is a system that includes a liquid handler that applies samples of genetic material to a test plate comprising an array of wells, a Polymerase Chain Reaction (PCR) device that amplifies the genetic material, and an analysis device that determines, based on a change in visual appearance of each well, a numerical value indicating whether a corresponding sample is representative of a disease state. The system also includes a quality assurance server that identifies a pattern of the numerical values, and determines a likelihood of the pattern. In an event that the likelihood is less than a threshold value, the quality assurance server flags the test plate as potentially contaminated, and in an event that the likelihood exceeds the threshold value, the quality assurance server refrains from flagging the test plate as potentially contaminated.

Abstract: Systems and methods are provided for performing predictive assignments pertaining to genetic information. One embodiment is a system that includes a genetic prediction server. The genetic prediction server includes an interface that acquires records that each indicate one or more genetic variants determined to exist within an individual, and a controller. The controller selects one or more machine learning models that utilize the genetic variants as input, and loads the machine learning models. For each individual in the records: the controller predictively assigns at least one characteristic to that individual by operating the machine learning models based on at least one genetic variant indicated in the records for that individual. The controller also generates a report indicating at least one predictively assigned characteristic for at least one individual, and transmits a command via the interface for presenting the report at a display.

Abstract: A system is provided for communication between a mobile device and an Enterprise Network. A gateway provides an end-to-end connection between the gateway and the mobile device. A controller is adapted to interpret data from a proprietary protocol. The data is communicated between the Enterprise Network and the mobile device via the end-to-end connection.

Abstract: A system is provided for communication between a mobile device and an Enterprise Network. A gateway provides an end-to-end connection between the gateway and the mobile device. A controller is adapted to interpret data from a proprietary protocol. The data is communicated between the Enterprise Network and the mobile device via the end-to-end connection.

Abstract: A method of producing an electrode brain probe assembly, using a flexible substrate comprising a polymeric layer bearing a conductive material coating. Photolithography and electroplating are used to form a set of contacts and conductors on the polymeric layer of the flexible substrate. Also, the flexible substrate is shaped to have a distal end and to be at least 5 mm long, but less than 5 mm wide and less than 1 mm thick.

Abstract: An apparatus for simultaneously cutting and notching a pipe includes an upper knife assembly having a pipe cutting knife and notch cutting knives with cutting edges adjacent a surface of the pipe and a lower knife assembly having a pipe cutting knife and notch cutting knives with cutting edges adjacent an opposite surface of the pipe. A method for cutting and notching a pipe includes stopping the axial and rotational movement of a pipe and moving the lower knife assembly into an overlapping relation with the upper knife assembly. The notch cutting knives are also moved into a cutting position and the axial and rotational pipe movement is resumed.