Abstract: This invention concerns peptides binding to antibodies which show neutralizing activity against different strains and clinical isolates of HIV-1 and which inhibit the fusion of cells infected with HIV-1. These peptides are combined with an adjuvant, as recombinant fusion proteins, chemically coupled to carrier molecules, as recombinant chimeric viruses or as recombinant antibodies.
Type:
Grant
Filed:
April 17, 1997
Date of Patent:
February 2, 1999
Assignee:
Hermann Katinger
Inventors:
Hermann Katinger, Florian Ruker, Gottfried Himmler, Thomas Muster, Alexandra Trkola, Martin Purtscher, Georg Maiwald, Franz Steindl
Abstract: Novel human monoclonal anti-HIV-I antibodies and immunochemicals made from the antibodies and method of treating or preventing HIV-I infections.
Type:
Grant
Filed:
August 22, 1994
Date of Patent:
November 3, 1998
Assignee:
Hermann Katinger
Inventors:
Hermann Katinger, Alois Jungbauer, Franz Steindl, Andrea Buchacher
Abstract: This invention refers to peptides binding to antibodies that show neutralizing activity against different strains and clinical isolates of HIV-1 and that inhibit the fusion of cells caused by HIV-1. These peptides are applied with an adjuvant, as recombinant fusion proteins, chemically coupled to carrier molecules, as recombinant chimeric viruses or as recombinant antibodies.
Type:
Grant
Filed:
December 22, 1994
Date of Patent:
December 2, 1997
Assignee:
Hermann Katinger
Inventors:
Hermann Katinger, Florian Ruker, Gottfried Himmler, Thomas Muster, Alexandra Trkola, Martin Purtscher, Georg Maiwald, Franz Steindl
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