Patents Assigned to HERON NEUTRON MEDICAL CORP.
  • Publication number: 20240121880
    Abstract: A superconducting electromagnet component and an isochronous cyclotron including the same are provided. The superconducting electromagnet component includes a superconducting main coil, a superconducting trim coil group, and a superconducting focusing coil group. The superconducting main coil is disposed around the central axis and includes a median plane. The superconducting trim coil group is disposed in the superconducting main coil around the central axis. The superconducting focusing coil group is disposed on the superconducting trim coil group and includes first focusing coils and second focusing coils. The first focusing coils have a first fan-shaped structure and are disposed side by side around the central axis, and the current directions of two adjacent first focusing coils are opposite. The second focusing coils have a second fan-shaped structure and are correspondingly disposed in the first focusing coils, and the current directions of two adjacent second focusing coils are opposite.
    Type: Application
    Filed: October 3, 2023
    Publication date: April 11, 2024
    Applicant: Heron Neutron Medical Corp.
    Inventors: Shan-Haw CHIOU, Siao-Cing LIOU
  • Publication number: 20240066319
    Abstract: A dose control system, including a processing device configured to obtain the real drug concentration in plasma of a patient. The processing device is further configured to calculate the corrected dose rate distribution datum based on the real drug concentration in plasma and a set of correction coefficients. The processing device is further configured to calculate the irradiation time based on the corrected dose rate distribution datum and the prescribed dose distribution datum. The processing device is further configured to control the irradiation device to irradiate the patient for the irradiation time.
    Type: Application
    Filed: February 3, 2023
    Publication date: February 29, 2024
    Applicant: Heron Neutron Medical Corp.
    Inventor: Tzung-Yi LIN
  • Patent number: 11752360
    Abstract: A minimally invasive neutron beam generating device is provided. The minimally invasive neutron beam generating device includes a proton accelerator, a target, and a neutron moderator. The proton accelerator is connected to a first channel, the target is located at one end of the first channel, and the neutron moderator covers the end of the first channel so that the target is embedded in the neutron moderator. In addition, the neutron moderator includes an accommodating element for accommodating a moderating substance, and the accommodating element is retractable.
    Type: Grant
    Filed: April 14, 2020
    Date of Patent: September 12, 2023
    Assignee: HERON NEUTRON MEDICAL CORP.
    Inventors: Kuo Tung Tiao, Jyi Tyan Yeh, Zhen Fan You
  • Publication number: 20230234973
    Abstract: An intermediate is provided herein, and it has the structure shown in the formula (1) as follows: formula (1). In the formula (1), R1 is —Cl, —Br, —I, —OSO2CF3, —B(OH)2, or R2 is —F, —18F, —Cl, —Br, —I, —SnMe3, —SnBu3, —B(OH)2, or and A is a chiral auxiliary.
    Type: Application
    Filed: January 16, 2023
    Publication date: July 27, 2023
    Applicant: Heron Neutron Medical Corp.
    Inventors: Teng-San Hsieh, Yu-Hou Yu, Tzung-Yi Lin
  • Publication number: 20230050273
    Abstract: A dose planning system, which takes the drug concentration distribution in human organs/tissues as well as the atomic composition distribution of human organs/tissues into consideration, and calculates the neutron/photon dose distribution in human organs/tissues under this drug concentration distribution using the Monte Carlo Method. Thereby the neutron/photon dose distribution in the organs/tissues of the human subject is calculated more accurately.
    Type: Application
    Filed: April 1, 2022
    Publication date: February 16, 2023
    Applicant: Heron Neutron Medical Corp.
    Inventors: Tzung-Yi LIN, Yen-Wan Hsueh LIU
  • Patent number: 11521763
    Abstract: A heat dissipation structure includes a housing. The housing has a bottom surface, a liquid inlet channel, a liquid outlet channel and a protruding portion. The liquid inlet channel and the liquid outlet channel are located at two opposite ends of the housing and above the bottom surface. The liquid inlet channel and the liquid outlet channel extend along a first direction. The protruding portion is located between the liquid inlet channel and the liquid outlet channel and above the bottom surface. The protruding portion protrudes towards a direction away from the bottom surface. The protruding portion has a protruding surface facing away from the bottom surface. A distance between the protruding surface and the bottom surface is increased first and then decreased along the first direction.
    Type: Grant
    Filed: April 5, 2020
    Date of Patent: December 6, 2022
    Assignee: HERON NEUTRON MEDICAL CORP.
    Inventor: Jyi-Tyan Yeh
  • Patent number: 11510308
    Abstract: A neutron beam generating device includes a supporting base, an outer shell, a target material, and a first pipe. The outer shell surrounds a rotating axis, rotatable engages the supporting base, and has a first opening. The target material is disposed in the outer shell. The first pipe extends from the first opening of the outer shell along the rotating axis to the target material. The first pipe is configured to transmit an ion beam to bombard the target material to generate a neutron beam.
    Type: Grant
    Filed: May 4, 2020
    Date of Patent: November 22, 2022
    Assignee: HERON NEUTRON MEDICAL CORP.
    Inventors: Jyi-Tyan Yeh, Yen-Wan Hsueh Liu, Zhen-Fan You
  • Publication number: 20210322786
    Abstract: A minimally invasive neutron beam generating device is provided. The minimally invasive neutron beam generating device includes a proton accelerator, a target, and a neutron moderator. The proton accelerator is connected to a first channel, the target is located at one end of the first channel, and the neutron moderator covers the end of the first channel so that the target is embedded in the neutron moderator. In addition, the neutron moderator includes an accommodating element for accommodating a moderating substance, and the accommodating element is retractable.
    Type: Application
    Filed: April 14, 2020
    Publication date: October 21, 2021
    Applicant: Heron Neutron Medical Corp.
    Inventors: Kuo Tung TIAO, Jyi Tyan YEH, Zhen Fan YOU
  • Patent number: 11109476
    Abstract: A filter is provided. The filter includes a mixed layer. The mixed layer includes aluminum, magnesium fluoride, and lithium fluoride. The mixed layer is composed of 1 part by volume of magnesium fluoride, 0.25 to 1 parts by volume of aluminum, and 0.003 to 0.02 parts by volume of lithium fluoride.
    Type: Grant
    Filed: August 18, 2020
    Date of Patent: August 31, 2021
    Assignee: HERON NEUTRON MEDICAL CORP.
    Inventors: Yen-Wan Hsueh Liu, Zhen-Fan You, Sheng Yang, Jyi-Tyan Yeh
  • Publication number: 20200383198
    Abstract: A filter is provided. The filter includes a mixed layer. The mixed layer includes aluminum, magnesium fluoride, and lithium fluoride. The mixed layer is composed of 1 part by volume of magnesium fluoride, 0.25 to 1 parts by volume of aluminum, and 0.003 to 0.02 parts by volume of lithium fluoride.
    Type: Application
    Filed: August 18, 2020
    Publication date: December 3, 2020
    Applicant: HERON NEUTRON MEDICAL CORP.
    Inventors: Yen-Wan HSUEH LIU, Zhen-Fan YOU, Sheng YANG, Jyi-Tyan YEH
  • Patent number: 10791618
    Abstract: A neutron beam source generator is provided, which includes an accelerator connecting to a beryllium target through a channel, a filter and a collimator. The beryllium target is disposed at an end of the channel and adjacent to the filter. The filter is disposed between the beryllium target and the collimator. The channel and the beryllium target have an angle ? therebetween, and the angle ? is between 0° and 90°. The channel and the direction normal to the surface of the filter have an angle ? therebetween, and the angle ? is between 0° and 90°. The cross-section of the channel is not circular.
    Type: Grant
    Filed: August 9, 2017
    Date of Patent: September 29, 2020
    Assignee: HERON NEUTRON MEDICAL CORP.
    Inventors: Yen-Wan Hsueh Liu, Zhen-Fan You, Sheng Yang, Jyi-Tyan Yeh