Patents Assigned to HUBEI UNIVERSITY OF TECHNOLOGY
  • 4'-DEMETHYLEPIPODOPHYLLOTOXIN DERIVATIVE, PREPARATION METHOD AND USE THEREOF
    Publication number: 20130040967
    Abstract: A 4?-demethylepipodophyllotoxin derivative of formula(III) having anti-tumor activity is provided. After the activation of hydroxyl in position C4 of 4?-demethylepipodophyllotoxin, tetramethylpyrazine is introduced by transamination to obtain the 4?-demethylepipodophyllotoxin derivative which is preferably used to inhibit gastric cancer line BGC-823.
    Type: Application
    Filed: April 22, 2011
    Publication date: February 14, 2013
    Applicant: HUBEI UNIVERSITY OF TECHNOLOGY
    Inventor: YaJie Tang