Abstract: A device for a more effective pulverization of particles and/or agglomerates of a powdered inhalation medicament, comprises a chamber suitable for receiving medicament which is substantially closed at one end thereof. The chamber is provided with at least one air inlet port and a powdered medicament outlet port. The chamber is rotationally symmetrical in shape and preferably its cross-section perpendicular to the center axis thereof is substantially circular in shape. The chamber also is without substantial flow obstacles. The inlet and outlet ports are spaced from each other in the direction of the center axis of chamber, with the inlet port being designed to direct the air inflow into the vortex chamber substantially parallel to the tangent of the chamber.
Abstract: Process for the purification of hemin by dissolving raw hemin into 1,3-dimethyl-2-imidazolidinone (DMI), the mixture is allowed to cool in order to crystallize the hemin in the form of a 1:3-adduct of hemin and DMI, whereafter the adduct obtained is split by mixing the same with warm water, a lower alcohol or in a mixture thereof, or by heating in a vacuum, and the liberated hemin is recovered. The invention also concerns a novel hemin derivative, that is the 1:3-adduct of hemin and DMI, and a process for its preparation.
Abstract: Crystalline xylitol is added to a melt containing xylitol and other sugar alcohols, such as maltitol, lactitol, and hydrogenated glucose syrup. By careful control of temperature and the amounts of crystalline xylitol added to the molten mixture, hard candies with low tack and good dimensional stability result.
Abstract: The present invention relates to a method for the preparation of a new, physiologically active, water-soluble complex compound, hemin arginate or hemin lysinate. According to the invention crystalline hemin and one of the amino acids L-arginine or L-lysine, in a molar proportion of 1:3, are allowed to react at room temperature under vigorous stirring for 10 to 15 hours in a solvent mixture of acetone and water in a ratio of 300:20 v/v. The hemin arginate or hemin lysinate thus formed is a powdery, stable compound suitable for use as raw material in tablets or capsules or as dry substance for preparation of injections for treatment of various types of anemia, including iron deficiency anemia and anemias and diseases associated with defects in heme synthesis.
Type:
Grant
Filed:
December 2, 1985
Date of Patent:
April 16, 1991
Assignee:
Huhtamaki Oy
Inventors:
Grels D. Ingberg, Ritva L. A. Penttila, Reino O. Tokola, Raimo Tenhunen
Abstract: The invention relates to a cassette system for inserting a rod inside a tubular basic element. The system consists of at least two elongated plate-shaped cassettes provided with transverse channels as well as of a shank whereby the rods placed in channels of one cassette can be pushed into the tubular basic elements placed in channels of the other cassette after placing the cassettes in alignment with each other. The invention relates also to an apparatus for manufacturing a subcutaneous prophylactic capsule, comprising a tubular basic element and a hormone rod placed therein.
Type:
Grant
Filed:
December 27, 1988
Date of Patent:
May 1, 1990
Assignee:
Huhtamaki Oy
Inventors:
Mikko V. Ristimaki, Matti J. Lehtinen, Krister J. Lindstrom, Rolf R. Hartzell
Abstract: Disposable mug of conical shape, the kind of which mugs may be assembled, by placing them within each other, to stacks fitting in an automatic dispenser, and which mug comprises projections provided on the side of the mug and a handle lying substantially parallel to the side and which may be formed into a grip by bending it. On the side of the mug projections have been formed substantially annularly both above and below the handle and that the extension of said projections is at least equal to the thickness of the handle.