Patents Assigned to HUNAN SIWEIKANG THERAPEUTICS CO. LTD
  • MODIFICATION OF IMMUNE CELLS FOR REDUCING TOXICITY AND USES THEREOF IN ADOPTIVE CELL THERAPY
    Publication number: 20240141292
    Abstract: A population of immune cells comprising modified immune cells with reduced inflammatory properties, wherein such modified immune cells may have reduced production of one or more inflammatory cytokines (e.g., interleukin 2), and/or express one or more antagonists of one or more inflammatory cytokines (e.g., interleukin 6). Also provided herein are methods of producing such immune cell populations comprising the modified immune cells and methods of using such in cell therapy (e.g., to treat cancer, infectious diseases or immune diseases).
    Type: Application
    Filed: January 11, 2024
    Publication date: May 2, 2024
    Applicant: HUNAN SIWEIKANG THERAPEUTICS CO. LTD
    Inventor: Biliang Hu
  • Modification of immune cells for reducing toxicity and uses thereof in adoptive cell therapy
    Patent number: 11965176
    Abstract: A population of immune cells comprising modified immune cells with reduced inflammatory properties, wherein such modified immune cells may have reduced production of one or more inflammatory cytokines (e.g., interleukin 2) and/or express one or more antagonists of one or more inflammatory cytokines (e.g., interleukin 6). Also provided herein are methods of producing such immune cell populations comprising the modified immune cells and methods of using such in cell therapy (e.g., to treat cancer, infectious diseases or immune diseases).
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: April 23, 2024
    Assignee: HUNAN SIWEIKANG THERAPEUTICS CO. LTD
    Inventor: Biliang Hu