Patents Assigned to Hyperfine Research, Inc.
  • Patent number: 10585156
    Abstract: Some aspects include a method of detecting change in degree of midline shift in a brain of a patient. The method comprises, while the patient remains positioned within the low-field magnetic resonance imaging device, acquiring first magnetic resonance (MR) image data and second MR image data of the patient's brain; providing the first and second MR data as input to a trained statistical classifier to obtain corresponding first and second output, identifying, from the first output, at least one initial location of at least one landmark associated with at least one midline structure of the patient's brain; identifying, from the second output, at least one updated location of the at least one landmark; and determining a degree of change in the midline shift using the at least one initial location of the at least one landmark and the at least one updated location of the at least one landmark.
    Type: Grant
    Filed: August 29, 2018
    Date of Patent: March 10, 2020
    Assignee: Hyperfine Research, Inc.
    Inventors: Michal Sofka, Jonathan M. Rothberg, Gregory L. Charvat, Tyler S. Ralston
  • Patent number: 10585153
    Abstract: According to some aspects, a magnetic resonance imaging system comprising a B0 magnet configured to produce a B0 magnetic field for the magnetic resonance imaging system, the B0 magnet comprising at least one first B0 magnet to produce a magnetic field to contribute to the B0 magnetic field for the magnetic resonance imaging system, at least one second B0 magnet to produce a magnetic field to contribute to the B0 magnetic field for the magnetic resonance imaging system, wherein the at least one first B0 magnet and the at least one second B0 magnet are arranged relative to one another so that an imaging region is provided there between, a surface configured to support a patient anatomy within the imaging region, and a positioning member coupled to the B0 magnet and configured to allow the B0 magnet to be tilted to position the planar surface at a corresponding incline.
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: March 10, 2020
    Assignee: Hyperfine Research, Inc.
    Inventors: Christopher Thomas McNulty, Michael Stephen Poole
  • Publication number: 20200064427
    Abstract: According to some aspects, a low-field magnetic resonance imaging system is provided. The low-field magnetic resonance imaging system comprises a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, the magnetics system comprising, a B0 magnet configured to produce a B0 field for the magnetic resonance imaging system at a low-field strength of less than 0.
    Type: Application
    Filed: October 29, 2019
    Publication date: February 27, 2020
    Applicant: Hyperfine Research, Inc.
    Inventors: Michael Stephen Poole, Cedric Hugon, Hadrien A. Dyvorne, Laura Sacolick, William J. Mileski, Jeremy Christopher Jordan, Alan B. Katze, JR., Jonathan M. Rothberg, Todd Rearick, Christopher Thomas McNulty
  • Patent number: 10564239
    Abstract: According to some aspects, a low-field magnetic resonance imaging system is provided. The low-field magnetic resonance imaging system comprises a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, the magnetics system comprising, a B0 magnet configured to produce a B0 field for the magnetic resonance imaging system at a low-field strength of less than 0.
    Type: Grant
    Filed: February 13, 2019
    Date of Patent: February 18, 2020
    Assignee: Hyperfine Research, Inc.
    Inventors: Michael Stephen Poole, Cedric Hugon, Christopher Thomas McNulty
  • Publication number: 20200041588
    Abstract: Methods and apparatus for operating a low-field magnetic resonance imaging (MRI) system to perform diffusion weighted imaging, the low-field MRI system including a plurality of magnetics components including a B0 magnet configured to produce a low-field main magnetic field B0, at least one gradient coil configured to, when operated, provide spatial encoding of emitted magnetic resonance signals, and at least one radio frequency (RF) component configured to acquire, when operated, the emitted magnetic resonance signals. The method comprises controlling one or more of the plurality of magnetics components in accordance with at least one pulse sequence having a diffusion-weighted gradient encoding period followed by multiple echo periods during which magnetic resonance signals are produced and detected, wherein at least two of the multiple echo periods correspond to respective encoded echoes having an opposite gradient polarity.
    Type: Application
    Filed: July 31, 2019
    Publication date: February 6, 2020
    Applicant: Hyperfine Research, Inc.
    Inventors: Rafael O'Halloran, Laura Sacolick
  • Patent number: 10551452
    Abstract: Some aspects comprise a tuning system configured to tune a radio frequency coil for use with a magnetic resonance imaging system comprising a tuning circuit including at least one tuning element configured to affect a frequency at which the radio frequency coil resonates, and a controller configured to set at least one value for the tuning element to cause the radio frequency coil to resonate at approximately a Larmor frequency of the magnetic resonance imaging system determined by the tuning system. Some aspects include a method of automatically tuning a radio frequency coil comprising determining information indicative of a Larmor frequency of the magnetic resonance imaging system, using a controller to automatically set at least one value of a tuning circuit to cause the radio frequency coil to resonate at approximately the Larmor frequency based on the determined information.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: February 4, 2020
    Assignee: Hyperfine Research, Inc.
    Inventors: Todd Rearick, Jeremy Christopher Jordan, Gregory L. Charvat, Matthew Scot Rosen
  • Patent number: 10545207
    Abstract: According to some aspects, a low-field magnetic resonance imaging system is provided. The low-field magnetic resonance imaging system comprises a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, the magnetics system comprising, a B0 magnet configured to produce a B0 field for the magnetic resonance imaging system at a low-field strength of less than 0.
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: January 28, 2020
    Assignee: Hyperfine Research, Inc.
    Inventors: Michael Stephen Poole, Cedric Hugon
  • Publication number: 20200025851
    Abstract: According to some aspects, a method of suppressing noise in an environment of a magnetic resonance imaging system is provided. The method comprising estimating a transfer function based on multiple calibration measurements obtained from the environment by at least one primary coil and at least one auxiliary sensor, respectively, estimating noise present in a magnetic resonance signal received by the at least one primary coil based at least in part on the transfer function, and suppressing noise in the magnetic resonance signal using the noise estimate.
    Type: Application
    Filed: September 25, 2019
    Publication date: January 23, 2020
    Applicant: Hyperfine Research, Inc.
    Inventors: Todd Rearick, Gregory L. Charvat, Matthew Scot Rosen, Jonathan M. Rothberg
  • Patent number: 10539637
    Abstract: According to some aspects, a portable magnetic resonance imaging system is provided, comprising a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging. The magnetics system comprises a permanent B0 magnet configured to produce a B0 field for the magnetic resonance imaging system, and a plurality of gradient coils configured to, when operated, generate magnetic fields to provide spatial encoding of emitted magnetic resonance signals, a power system comprising one or more power components configured to provide power to the magnetics system to operate the magnetic resonance imaging system to perform image acquisition, and a base that supports the magnetics system and houses the power system, the base comprising at least one conveyance mechanism allowing the portable magnetic resonance imaging system to be transported to different locations.
    Type: Grant
    Filed: January 24, 2018
    Date of Patent: January 21, 2020
    Assignee: Hyperfine Research, Inc.
    Inventors: Michael Stephen Poole, Cedric Hugon, Hadrien A. Dyvorne, Laura Sacolick, William J. Mileski, Jeremy Christopher Jordan, Alan B. Katze, Jr., Jonathan M. Rothberg, Todd Rearick, Christopher Thomas McNulty
  • Publication number: 20200018806
    Abstract: According to some aspects, a laminate panel is provided. The laminate panel comprises at least one laminate layer including at least one non-conductive layer and at least one conductive layer patterned to form at least a portion of a B0 coil configured to contribute to a B0 field suitable for use in low-field magnetic resonance imaging (MRI).
    Type: Application
    Filed: September 25, 2019
    Publication date: January 16, 2020
    Applicant: Hyperfine Research, Inc.
    Inventors: Jonathan M. Rothberg, Matthew Scot Rosen, Gregory L. Charvat, William J. Mileski, Todd Rearick, Michael Stephen Poole, Keith G. Fife
  • Patent number: 10534058
    Abstract: Some aspects include a method of determining change in size of an abnormality in a brain of a patient positioned within a low-field magnetic resonance imaging (MRI) device. The method comprises, while the patient remains positioned within the low-field MRI device, acquiring first and second magnetic resonance (MR) image data of the patient's brain; providing the first and second MR image data as input to a trained statistical classifier to obtain corresponding first and second output; identifying, using the first output, at least one initial value of at least one feature indicative of a size of the abnormality; identifying, using the second output, at least one updated value of the at least one feature; determining the change in the size of the abnormality using the at least one initial value of the at least one feature and the at least one updated value of the at least one feature.
    Type: Grant
    Filed: August 29, 2018
    Date of Patent: January 14, 2020
    Assignee: Hyperfine Research, Inc.
    Inventors: Michal Sofka, Jonathan M. Rothberg, Gregory L. Charvat, Tyler S. Ralston
  • Publication number: 20200011952
    Abstract: In some aspects, a method of operating a magnetic resonance imaging system comprising a B0 magnet and at least one thermal management component configured to transfer heat away from the B0 magnet during operation is provided. The method comprises providing operating power to the B0 magnet, monitoring a temperature of the B0 magnet to determine a current temperature of the B0 magnet, and operating the at least one thermal management component at less than operational capacity in response to an occurrence of at least one event.
    Type: Application
    Filed: September 18, 2019
    Publication date: January 9, 2020
    Applicant: Hyperfine Research, Inc.
    Inventors: Jonathan M. Rothberg, Jeremy Christopher Jordan, Michael Stephen Poole, Laura Sacolick, Todd Rearick, Gregory L. Charvat
  • Patent number: 10527692
    Abstract: According to some aspects, a magnetic resonance imaging system comprising a B0 magnet configured to produce a B0 magnetic field for the magnetic resonance imaging system, the B0 magnet comprising at least one first B0 magnet to produce a magnetic field to contribute to the B0 magnetic field for the magnetic resonance imaging system, at least one second B0 magnet to produce a magnetic field to contribute to the B0 magnetic field for the magnetic resonance imaging system, wherein the at least one first B0 magnet and the at least one second B0 magnet are arranged relative to one another so that an imaging region is provided there between, a surface configured to support a patient anatomy within the imaging region, and a positioning member coupled to the B0 magnet and configured to allow the B0 magnet to be tilted to position the planar surface at a corresponding incline.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: January 7, 2020
    Assignee: Hyperfine Research, Inc.
    Inventors: Christopher Thomas McNulty, Michael Stephen Poole
  • Patent number: 10520566
    Abstract: According to some aspects, a low-field magnetic resonance imaging system is provided. The low-field magnetic resonance imaging system comprises a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, the magnetics system comprising, a B0 magnet configured to produce a B0 field for the magnetic resonance imaging system at a low-field strength of less than 0.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: December 31, 2019
    Assignee: Hyperfine Research, Inc.
    Inventors: Michael Stephen Poole, Cedric Hugon, Hadrien A. Dyvorne, Laura Sacolick, William J. Mileski, Jeremy Christopher Jordan, Alan B. Katze, Jr., Jonathan M. Rothberg, Todd Rearick, Christopher Thomas McNulty
  • Patent number: 10495712
    Abstract: According to some aspects, a laminate panel is provided. The laminate panel comprises at least one laminate layer including at least one non-conductive layer and at least one conductive layer patterned to form at least a portion of a B0 coil configured to contribute to a B0 field suitable for use in low-field magnetic resonance imaging (MRI).
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: December 3, 2019
    Assignee: Hyperfine Research, Inc.
    Inventors: Jonathan M. Rothberg, Matthew Scot Rosen, Gregory L. Charvat, William J. Mileski, Todd Rearick, Michael Stephen Poole, Keith G. Fife
  • Patent number: 10488482
    Abstract: According to some aspects, a method of suppressing noise in an environment of a magnetic resonance imaging system is provided. The method comprising estimating a transfer function based on multiple calibration measurements obtained from the environment by at least one primary coil and at least one auxiliary sensor, respectively, estimating noise present in a magnetic resonance signal received by the at least one primary coil based at least in part on the transfer function, and suppressing noise in the magnetic resonance signal using the noise estimate.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: November 26, 2019
    Assignee: Hyperfine Research, Inc.
    Inventors: Todd Rearick, Gregory L. Charvat, Matthew Scot Rosen, Jonathan M. Rothberg
  • Publication number: 20190353720
    Abstract: Methods and apparatus for reducing noise in RF signal chain circuitry for a low-field magnetic resonance imaging system are provided. A switching circuit in the RF signal chain circuitry may include at least one field effect transistor (FET) configured to operate as an RF switch at an operating frequency of less than 10 MHz. A decoupling circuit may include tuning circuitry coupled across inputs of an amplifier and active feedback circuitry coupled between an output of the amplifier and an input of the amplifier, wherein the active feedback circuitry includes a feedback capacitor configured to reduce a quality factor of an RF coil coupled to the amplifier.
    Type: Application
    Filed: May 21, 2019
    Publication date: November 21, 2019
    Applicant: Hyperfine Research, Inc.
    Inventors: Hadrien A. Dyvorne, Todd Rearick
  • Publication number: 20190353727
    Abstract: Methods and apparatus for reducing noise in RF signal chain circuitry for a low-field magnetic resonance imaging system are provided. A switching circuit in the RF signal chain circuitry may include at least one field effect transistor (FET) configured to operate as an RF switch at an operating frequency of less than 10 MHz. A decoupling circuit may include tuning circuitry coupled across inputs of an amplifier and active feedback circuitry coupled between an output of the amplifier and an input of the amplifier, wherein the active feedback circuitry includes a feedback capacitor configured to reduce a quality factor of an RF coil coupled to the amplifier.
    Type: Application
    Filed: May 21, 2019
    Publication date: November 21, 2019
    Applicant: Hyperfine Research, Inc.
    Inventors: Hadrien A. Dyvorne, Todd Rearick
  • Publication number: 20190353723
    Abstract: Methods and apparatus for reducing noise in RF signal chain circuitry for a low-field magnetic resonance imaging system are provided. A switching circuit in the RF signal chain circuitry may include at least one field effect transistor (FET) configured to operate as an RF switch at an operating frequency of less than 10 MHz. A decoupling circuit may include tuning circuitry coupled across inputs of an amplifier and active feedback circuitry coupled between an output of the amplifier and an input of the amplifier, wherein the active feedback circuitry includes a feedback capacitor configured to reduce a quality factor of an RF coil coupled to the amplifier.
    Type: Application
    Filed: May 21, 2019
    Publication date: November 21, 2019
    Applicant: Hyperfine Research, Inc.
    Inventors: Hadrien A. Dyvorne, Todd Rearick
  • Patent number: 10466327
    Abstract: In some aspects, a method of operating a magnetic resonance imaging system comprising a B0 magnet and at least one thermal management component configured to transfer heat away from the B0 magnet during operation is provided. The method comprises providing operating power to the B0 magnet, monitoring a temperature of the B0 magnet to determine a current temperature of the B0 magnet, and operating the at least one thermal management component at less than operational capacity in response to an occurrence of at least one event.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: November 5, 2019
    Assignee: Hyperfine Research, Inc.
    Inventors: Jonathan M. Rothberg, Jeremy Christopher Jordan, Michael Stephen Poole, Laura Sacolick, Todd Rearick, Gregory L. Charvat