Patents Assigned to Hyperfine Research, Inc.
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Patent number: 10585156Abstract: Some aspects include a method of detecting change in degree of midline shift in a brain of a patient. The method comprises, while the patient remains positioned within the low-field magnetic resonance imaging device, acquiring first magnetic resonance (MR) image data and second MR image data of the patient's brain; providing the first and second MR data as input to a trained statistical classifier to obtain corresponding first and second output, identifying, from the first output, at least one initial location of at least one landmark associated with at least one midline structure of the patient's brain; identifying, from the second output, at least one updated location of the at least one landmark; and determining a degree of change in the midline shift using the at least one initial location of the at least one landmark and the at least one updated location of the at least one landmark.Type: GrantFiled: August 29, 2018Date of Patent: March 10, 2020Assignee: Hyperfine Research, Inc.Inventors: Michal Sofka, Jonathan M. Rothberg, Gregory L. Charvat, Tyler S. Ralston
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Patent number: 10585153Abstract: According to some aspects, a magnetic resonance imaging system comprising a B0 magnet configured to produce a B0 magnetic field for the magnetic resonance imaging system, the B0 magnet comprising at least one first B0 magnet to produce a magnetic field to contribute to the B0 magnetic field for the magnetic resonance imaging system, at least one second B0 magnet to produce a magnetic field to contribute to the B0 magnetic field for the magnetic resonance imaging system, wherein the at least one first B0 magnet and the at least one second B0 magnet are arranged relative to one another so that an imaging region is provided there between, a surface configured to support a patient anatomy within the imaging region, and a positioning member coupled to the B0 magnet and configured to allow the B0 magnet to be tilted to position the planar surface at a corresponding incline.Type: GrantFiled: April 18, 2018Date of Patent: March 10, 2020Assignee: Hyperfine Research, Inc.Inventors: Christopher Thomas McNulty, Michael Stephen Poole
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Publication number: 20200064427Abstract: According to some aspects, a low-field magnetic resonance imaging system is provided. The low-field magnetic resonance imaging system comprises a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, the magnetics system comprising, a B0 magnet configured to produce a B0 field for the magnetic resonance imaging system at a low-field strength of less than 0.Type: ApplicationFiled: October 29, 2019Publication date: February 27, 2020Applicant: Hyperfine Research, Inc.Inventors: Michael Stephen Poole, Cedric Hugon, Hadrien A. Dyvorne, Laura Sacolick, William J. Mileski, Jeremy Christopher Jordan, Alan B. Katze, JR., Jonathan M. Rothberg, Todd Rearick, Christopher Thomas McNulty
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Patent number: 10564239Abstract: According to some aspects, a low-field magnetic resonance imaging system is provided. The low-field magnetic resonance imaging system comprises a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, the magnetics system comprising, a B0 magnet configured to produce a B0 field for the magnetic resonance imaging system at a low-field strength of less than 0.Type: GrantFiled: February 13, 2019Date of Patent: February 18, 2020Assignee: Hyperfine Research, Inc.Inventors: Michael Stephen Poole, Cedric Hugon, Christopher Thomas McNulty
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Publication number: 20200041588Abstract: Methods and apparatus for operating a low-field magnetic resonance imaging (MRI) system to perform diffusion weighted imaging, the low-field MRI system including a plurality of magnetics components including a B0 magnet configured to produce a low-field main magnetic field B0, at least one gradient coil configured to, when operated, provide spatial encoding of emitted magnetic resonance signals, and at least one radio frequency (RF) component configured to acquire, when operated, the emitted magnetic resonance signals. The method comprises controlling one or more of the plurality of magnetics components in accordance with at least one pulse sequence having a diffusion-weighted gradient encoding period followed by multiple echo periods during which magnetic resonance signals are produced and detected, wherein at least two of the multiple echo periods correspond to respective encoded echoes having an opposite gradient polarity.Type: ApplicationFiled: July 31, 2019Publication date: February 6, 2020Applicant: Hyperfine Research, Inc.Inventors: Rafael O'Halloran, Laura Sacolick
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Patent number: 10551452Abstract: Some aspects comprise a tuning system configured to tune a radio frequency coil for use with a magnetic resonance imaging system comprising a tuning circuit including at least one tuning element configured to affect a frequency at which the radio frequency coil resonates, and a controller configured to set at least one value for the tuning element to cause the radio frequency coil to resonate at approximately a Larmor frequency of the magnetic resonance imaging system determined by the tuning system. Some aspects include a method of automatically tuning a radio frequency coil comprising determining information indicative of a Larmor frequency of the magnetic resonance imaging system, using a controller to automatically set at least one value of a tuning circuit to cause the radio frequency coil to resonate at approximately the Larmor frequency based on the determined information.Type: GrantFiled: September 29, 2017Date of Patent: February 4, 2020Assignee: Hyperfine Research, Inc.Inventors: Todd Rearick, Jeremy Christopher Jordan, Gregory L. Charvat, Matthew Scot Rosen
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Patent number: 10545207Abstract: According to some aspects, a low-field magnetic resonance imaging system is provided. The low-field magnetic resonance imaging system comprises a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, the magnetics system comprising, a B0 magnet configured to produce a B0 field for the magnetic resonance imaging system at a low-field strength of less than 0.Type: GrantFiled: April 18, 2018Date of Patent: January 28, 2020Assignee: Hyperfine Research, Inc.Inventors: Michael Stephen Poole, Cedric Hugon
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Publication number: 20200025851Abstract: According to some aspects, a method of suppressing noise in an environment of a magnetic resonance imaging system is provided. The method comprising estimating a transfer function based on multiple calibration measurements obtained from the environment by at least one primary coil and at least one auxiliary sensor, respectively, estimating noise present in a magnetic resonance signal received by the at least one primary coil based at least in part on the transfer function, and suppressing noise in the magnetic resonance signal using the noise estimate.Type: ApplicationFiled: September 25, 2019Publication date: January 23, 2020Applicant: Hyperfine Research, Inc.Inventors: Todd Rearick, Gregory L. Charvat, Matthew Scot Rosen, Jonathan M. Rothberg
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Patent number: 10539637Abstract: According to some aspects, a portable magnetic resonance imaging system is provided, comprising a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging. The magnetics system comprises a permanent B0 magnet configured to produce a B0 field for the magnetic resonance imaging system, and a plurality of gradient coils configured to, when operated, generate magnetic fields to provide spatial encoding of emitted magnetic resonance signals, a power system comprising one or more power components configured to provide power to the magnetics system to operate the magnetic resonance imaging system to perform image acquisition, and a base that supports the magnetics system and houses the power system, the base comprising at least one conveyance mechanism allowing the portable magnetic resonance imaging system to be transported to different locations.Type: GrantFiled: January 24, 2018Date of Patent: January 21, 2020Assignee: Hyperfine Research, Inc.Inventors: Michael Stephen Poole, Cedric Hugon, Hadrien A. Dyvorne, Laura Sacolick, William J. Mileski, Jeremy Christopher Jordan, Alan B. Katze, Jr., Jonathan M. Rothberg, Todd Rearick, Christopher Thomas McNulty
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Publication number: 20200018806Abstract: According to some aspects, a laminate panel is provided. The laminate panel comprises at least one laminate layer including at least one non-conductive layer and at least one conductive layer patterned to form at least a portion of a B0 coil configured to contribute to a B0 field suitable for use in low-field magnetic resonance imaging (MRI).Type: ApplicationFiled: September 25, 2019Publication date: January 16, 2020Applicant: Hyperfine Research, Inc.Inventors: Jonathan M. Rothberg, Matthew Scot Rosen, Gregory L. Charvat, William J. Mileski, Todd Rearick, Michael Stephen Poole, Keith G. Fife
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Patent number: 10534058Abstract: Some aspects include a method of determining change in size of an abnormality in a brain of a patient positioned within a low-field magnetic resonance imaging (MRI) device. The method comprises, while the patient remains positioned within the low-field MRI device, acquiring first and second magnetic resonance (MR) image data of the patient's brain; providing the first and second MR image data as input to a trained statistical classifier to obtain corresponding first and second output; identifying, using the first output, at least one initial value of at least one feature indicative of a size of the abnormality; identifying, using the second output, at least one updated value of the at least one feature; determining the change in the size of the abnormality using the at least one initial value of the at least one feature and the at least one updated value of the at least one feature.Type: GrantFiled: August 29, 2018Date of Patent: January 14, 2020Assignee: Hyperfine Research, Inc.Inventors: Michal Sofka, Jonathan M. Rothberg, Gregory L. Charvat, Tyler S. Ralston
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Publication number: 20200011952Abstract: In some aspects, a method of operating a magnetic resonance imaging system comprising a B0 magnet and at least one thermal management component configured to transfer heat away from the B0 magnet during operation is provided. The method comprises providing operating power to the B0 magnet, monitoring a temperature of the B0 magnet to determine a current temperature of the B0 magnet, and operating the at least one thermal management component at less than operational capacity in response to an occurrence of at least one event.Type: ApplicationFiled: September 18, 2019Publication date: January 9, 2020Applicant: Hyperfine Research, Inc.Inventors: Jonathan M. Rothberg, Jeremy Christopher Jordan, Michael Stephen Poole, Laura Sacolick, Todd Rearick, Gregory L. Charvat
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Patent number: 10527692Abstract: According to some aspects, a magnetic resonance imaging system comprising a B0 magnet configured to produce a B0 magnetic field for the magnetic resonance imaging system, the B0 magnet comprising at least one first B0 magnet to produce a magnetic field to contribute to the B0 magnetic field for the magnetic resonance imaging system, at least one second B0 magnet to produce a magnetic field to contribute to the B0 magnetic field for the magnetic resonance imaging system, wherein the at least one first B0 magnet and the at least one second B0 magnet are arranged relative to one another so that an imaging region is provided there between, a surface configured to support a patient anatomy within the imaging region, and a positioning member coupled to the B0 magnet and configured to allow the B0 magnet to be tilted to position the planar surface at a corresponding incline.Type: GrantFiled: April 24, 2019Date of Patent: January 7, 2020Assignee: Hyperfine Research, Inc.Inventors: Christopher Thomas McNulty, Michael Stephen Poole
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Patent number: 10520566Abstract: According to some aspects, a low-field magnetic resonance imaging system is provided. The low-field magnetic resonance imaging system comprises a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, the magnetics system comprising, a B0 magnet configured to produce a B0 field for the magnetic resonance imaging system at a low-field strength of less than 0.Type: GrantFiled: November 22, 2017Date of Patent: December 31, 2019Assignee: Hyperfine Research, Inc.Inventors: Michael Stephen Poole, Cedric Hugon, Hadrien A. Dyvorne, Laura Sacolick, William J. Mileski, Jeremy Christopher Jordan, Alan B. Katze, Jr., Jonathan M. Rothberg, Todd Rearick, Christopher Thomas McNulty
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Patent number: 10495712Abstract: According to some aspects, a laminate panel is provided. The laminate panel comprises at least one laminate layer including at least one non-conductive layer and at least one conductive layer patterned to form at least a portion of a B0 coil configured to contribute to a B0 field suitable for use in low-field magnetic resonance imaging (MRI).Type: GrantFiled: September 29, 2017Date of Patent: December 3, 2019Assignee: Hyperfine Research, Inc.Inventors: Jonathan M. Rothberg, Matthew Scot Rosen, Gregory L. Charvat, William J. Mileski, Todd Rearick, Michael Stephen Poole, Keith G. Fife
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Patent number: 10488482Abstract: According to some aspects, a method of suppressing noise in an environment of a magnetic resonance imaging system is provided. The method comprising estimating a transfer function based on multiple calibration measurements obtained from the environment by at least one primary coil and at least one auxiliary sensor, respectively, estimating noise present in a magnetic resonance signal received by the at least one primary coil based at least in part on the transfer function, and suppressing noise in the magnetic resonance signal using the noise estimate.Type: GrantFiled: November 19, 2018Date of Patent: November 26, 2019Assignee: Hyperfine Research, Inc.Inventors: Todd Rearick, Gregory L. Charvat, Matthew Scot Rosen, Jonathan M. Rothberg
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Publication number: 20190353720Abstract: Methods and apparatus for reducing noise in RF signal chain circuitry for a low-field magnetic resonance imaging system are provided. A switching circuit in the RF signal chain circuitry may include at least one field effect transistor (FET) configured to operate as an RF switch at an operating frequency of less than 10 MHz. A decoupling circuit may include tuning circuitry coupled across inputs of an amplifier and active feedback circuitry coupled between an output of the amplifier and an input of the amplifier, wherein the active feedback circuitry includes a feedback capacitor configured to reduce a quality factor of an RF coil coupled to the amplifier.Type: ApplicationFiled: May 21, 2019Publication date: November 21, 2019Applicant: Hyperfine Research, Inc.Inventors: Hadrien A. Dyvorne, Todd Rearick
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Publication number: 20190353727Abstract: Methods and apparatus for reducing noise in RF signal chain circuitry for a low-field magnetic resonance imaging system are provided. A switching circuit in the RF signal chain circuitry may include at least one field effect transistor (FET) configured to operate as an RF switch at an operating frequency of less than 10 MHz. A decoupling circuit may include tuning circuitry coupled across inputs of an amplifier and active feedback circuitry coupled between an output of the amplifier and an input of the amplifier, wherein the active feedback circuitry includes a feedback capacitor configured to reduce a quality factor of an RF coil coupled to the amplifier.Type: ApplicationFiled: May 21, 2019Publication date: November 21, 2019Applicant: Hyperfine Research, Inc.Inventors: Hadrien A. Dyvorne, Todd Rearick
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Publication number: 20190353723Abstract: Methods and apparatus for reducing noise in RF signal chain circuitry for a low-field magnetic resonance imaging system are provided. A switching circuit in the RF signal chain circuitry may include at least one field effect transistor (FET) configured to operate as an RF switch at an operating frequency of less than 10 MHz. A decoupling circuit may include tuning circuitry coupled across inputs of an amplifier and active feedback circuitry coupled between an output of the amplifier and an input of the amplifier, wherein the active feedback circuitry includes a feedback capacitor configured to reduce a quality factor of an RF coil coupled to the amplifier.Type: ApplicationFiled: May 21, 2019Publication date: November 21, 2019Applicant: Hyperfine Research, Inc.Inventors: Hadrien A. Dyvorne, Todd Rearick
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Patent number: 10466327Abstract: In some aspects, a method of operating a magnetic resonance imaging system comprising a B0 magnet and at least one thermal management component configured to transfer heat away from the B0 magnet during operation is provided. The method comprises providing operating power to the B0 magnet, monitoring a temperature of the B0 magnet to determine a current temperature of the B0 magnet, and operating the at least one thermal management component at less than operational capacity in response to an occurrence of at least one event.Type: GrantFiled: December 3, 2018Date of Patent: November 5, 2019Assignee: Hyperfine Research, Inc.Inventors: Jonathan M. Rothberg, Jeremy Christopher Jordan, Michael Stephen Poole, Laura Sacolick, Todd Rearick, Gregory L. Charvat