Patents Assigned to I.B.R. Israeli Biotechnology Research, Ltd.
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Patent number: 10576116Abstract: The present invention relates to extracts derived from plants and/or fractions thereof, compositions comprising same and use thereof in protecting tissues from damages caused by exogenous toxins. In particular, the present invention relates to polar extract and/or fraction thereof derived from Asteriscus graveolens, compositions comprising same and use thereof in protecting tissues comprising epithelial cell from the deleterious effect of exogenous toxins, particularly toxins originating from environmental pollution.Type: GrantFiled: February 1, 2016Date of Patent: March 3, 2020Assignee: I.B.R. Israeli Biotechnology Research Ltd.Inventors: Ofir Ramot, Fabien Havas, Eyal Kalo, Liki Von Oppen-Bezalel, Raffi Arnon, Olga Ben-Chitrit, Inon Perry
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Patent number: 8398958Abstract: The present invention relates to use of carotenoid preparations for promoting skin whitening. Particularly, the present invention discloses that a combination of phytoene and phytofluene is effective in whitening skin. The present invention further relates to carotenoid compositions comprising a combination of phytofluene and phytofluene effective in whitening skin and at least one additional carotenoid, particularly carotenoids devoid of highly intense color.Type: GrantFiled: May 29, 2007Date of Patent: March 19, 2013Assignee: I.B.R. Israeli Biotechnology Research Ltd.Inventors: Liki Von Oppen Bezalel, Etienne Soudant, Inon Perry, Fumio Maniwa, Yuki Hata, Akemi Takayama
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Publication number: 20110171332Abstract: The present invention relates to Leucojum extracts, particularly to aqueous extract of Leucojum bulbs effective in inhibiting contraction of muscle cells or tissues and as an anti-oxidant, composition comprising same and use thereof for inhibiting muscle contractions, particularly cutaneous muscles effective in treating and preventing wrinkles, fine lines and oxidative damages of the skin.Type: ApplicationFiled: September 13, 2009Publication date: July 14, 2011Applicant: I.B.R. ISRAELI BIOTECHNOLOGY RESEARCH LTD.Inventors: Etienne Soudant, Danit Fishbein Manor, Alex Aliluiko, Lea Von Oppen-Bezalel, Inon Perry
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Patent number: 7482032Abstract: A preparation comprising the carotenoids phytoene and phytofluene in an amount which, in combination, is effective in preventing various kinds of damage resulting from oxidation and exposure to UV light is provided. The preparation is essentially colorless and may be used as a topical cosmetic or pharmaceutical preparation as well as an additive in food preparations. In addition, a method for producing substantive amounts of phytoene and phytofluene from carotenoid producing organisms is described as well.Type: GrantFiled: March 14, 2002Date of Patent: January 27, 2009Assignee: I.B.R. Israeli Biotechnology Research, Ltd.Inventors: Etienne Soudant, Lea Bezalel, Hedva Schickler, Judith Paltiel, Ami Ben-Amotz, Aviv Shaish, Inon Perry
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Patent number: 7479287Abstract: A dormant preparation (DC) is provided which is capable of inhibiting proliferation of various kinds of cells. The preparation comprises an extract which is obtained from cells or tissue originating in an organism capable of entering a phase of dormancy in at least one of its parts and comprises at least one substance which induces or maintains the state of dormancy in the organism from which the cells or tissue are derived. The DC may be used for a variety of indications including human medicine and cosmetics, plant growth control and food preservation.Type: GrantFiled: July 31, 2006Date of Patent: January 20, 2009Assignee: I.B.R., Israeli Biotechnology Research, Ltd.Inventors: Etienne Soudant, Lea Bezalel, Meira Ziv, Inon Perry
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Publication number: 20040047924Abstract: A dormant preparation (DC) is provided which is capable of inhibiting proliferation of various kinds of cells. The preparation comprises an extract which is obtained from cells or tissue originating in an organism capable of entering a phase of dormancy in at least one of its parts and comprises at least one substance which induces or maintains the state of dormancy in the organism from which the cells or tissue are derived. The DC may be used for a variety of indications including human medicine and cosmetics, plant growth control and food preservation.Type: ApplicationFiled: June 20, 2003Publication date: March 11, 2004Applicant: I.B.R. Israeli Biotechnology Research Ltd.Inventors: Etienne Soudant, Lea Bezalel, Meira Ziv, Inon Perry
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Patent number: 6635287Abstract: A dormant preparation (DC) is provided which is capable of inhibiting proliferation of various kinds of cells. The preparation comprises an extract which is obtained from cells or tissue originating in an organism capable of entering a phase of dormancy in at least one of its parts and comprises at least one substance which induces or maintains the state of dormancy in the organism from which the cells or tissue are derived. The DC may be used for a variety of indications including human medicine and cosmetics, plant growth control and food preservation.Type: GrantFiled: July 27, 2001Date of Patent: October 21, 2003Assignee: I.B.R. Israeli Biotechnology Research Ltd.Inventors: Etienne Soudant, Lea Bezalel, Meira Ziv, Inon Perry
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Publication number: 20020131940Abstract: A preparation comprising the carotenoids phytoene and phytofluene in an amount which, in combination, is effective in preventing various kinds of damage resulting from oxidation and exposure to UV light is provided. The preparation is essentially colorless and may be used as a topical cosmetic or pharmaceutical preparation as well as an additive in food preparations. In addition, a method for producing substantive amounts of phytoene and phytofluene from carotenoid producing organisms is described as well.Type: ApplicationFiled: March 14, 2002Publication date: September 19, 2002Applicant: I.B.R. ISRAELI BIOTECHNOLOGY RESEARCH, LTD.Inventors: Etienne Soudant, Lea Bezalel, Hedva Schickler, Judith Paltiel, Ami Ben-Amotz, Aviv Shaish, Inon Perry
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Publication number: 20020071878Abstract: A dormant preparation (DC) is provided which is capable of inhibiting proliferation of various kinds of cells. The preparation comprises an extract which is obtained from cells or tissue originating in an organism capable of entering a phase of dormancy in at least one of its parts and comprises at least one substance which induces or maintains the state of dormancy in the organism from which the cells or tissue are derived. The DC may be used for a variety of indications including human medicine and cosmetics, plant growth control and food preservation.Type: ApplicationFiled: July 27, 2001Publication date: June 13, 2002Applicant: I.B.R. Israeli Biotechnology Research Ltd.Inventors: Etienne Soudant, Lea Bezalel, Meira Ziv, Inon Perry
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Patent number: 6383474Abstract: A preparation comprising the carotenoids phytoene and phytofluene in an amount which, in combination, is effective in preventing various kinds of damage resulting from oxidation and exposure to UV light is provided. The preparation is essentially colorless and may be used as a topical cosmetic or pharmaceutical preparation as well as an additive in food preparations. In addition, a method for producing substantive amounts of phytoene and phytofluene from carotenoid producing organisms is described as well.Type: GrantFiled: May 18, 2001Date of Patent: May 7, 2002Assignee: I.B.R. Israeli Biotechnology Research, Ltd.Inventors: Etienne Soudant, Lea Bezalel, Hedva Schickler, Judith Paltiel, Ami Ben-Amotz, Aviv Shaish, Inon Perry
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Patent number: 6342254Abstract: A dormant preparation (DC) is provided which is capable of inhibiting proliferation of various kinds of cells. The preparation comprises an extract which is obtained from cells or tissue originating in an organism capable of entering a phase of dormancy in at least one of its parts and comprises at least one substance which induces or maintains the state of dormancy in the organism from which the cells or tissue are derived. The DC may be used for a variety of indications including human medicine and cosmetics, plant growth control and food preservation. A preferred dormant preparation is prepared from a water extract of Narcissus (daffodil) bulb.Type: GrantFiled: November 29, 1999Date of Patent: January 29, 2002Assignee: I.B.R. Israeli Biotechnology Research, Ltd.Inventors: Etienne Soudant, Lea Bezalel, Meira Ziv, Inon Perry