Abstract: The present invention is related to compositions containing extracellular vesicles (exosomes) and methods of using the same for increasing lifespan of fetus, viability of fetus, or viability of newborn, for treating inflammation in uterus and/or fetus, for delaying preterm birth, or for treating a condition related to inflammation in uterus and/or fetus, wherein the extracellular vesicles comprising a nuclear factor kappa beta (NF-?B) inhibitor and a photo-specific binding protein.
Type:
Grant
Filed:
December 30, 2020
Date of Patent:
July 11, 2023
Assignees:
ILIAS Biologics Inc., ILIAS Therapeutics, Inc.
Abstract: The present invention provides a method for producing an exosome that transfers an active substance specifically to a target and the exosome produced by the same; a method for delivering the active substance to the target tissue using the exosome; a pharmaceutical composition for delivery of the active substance comprising the exosome as an active ingredient; and a composition for preparing the exosome comprising an expression vector wherein the target peptide is inserted into an extracellular portion of a transmembrane protein.
Type:
Application
Filed:
August 16, 2018
Publication date:
July 2, 2020
Applicants:
ILIAS BIOLOGICS INC., ILIAS THERAPEUTICS, INC.