Abstract: Substance P or its analogs are useful for treating and protecting against acute respiratory syndromes including ARDS and SARS. The active agents can be administered via inhalation therapy, intravenously, intramuscularly, sublingually, or by other methods. Disease indicia are reduced by substance P treatment.

Abstract: Myelodysplastic syndromes can be treated or ameliorated by the administration of substance P analogs as disclosed herein.

Abstract: Compositions and methods are provided for stimulating cell proliferation and differentiation with substance P or a substance P analog. In one embodiment, the methods provide for stimulating or promoting stem cell differentiation by contacting a stem cell with substance P or a substance P analog. In another embodiment, the methods provide for administering to subject an effective amount of substance P or a substance P analog to treat an illness, disease or disorder.

Abstract: Neuropeptides are used to treat mammals which have depletion of count of one or more blood cell types. Intramuscular administration or administration via inhalation causes the blood cell count to increase.

Abstract: Provided herein are methods and compositions useful for the replenishment of blood cells in a mammal after exposure to therapeutic radiation or drugs. Radiation illness can be reduced in animals by treatment with substance P analogs. In one embodiment, granulocytes can be regenerated after therapeutic radiation by the administration of a substance P analog. In one embodiment, substance P analogs are useful for reducing PARP activity or PARP expression. In one embodiment, substance P analogs are useful for preventing, reducing or ameliorating adverse effects of drugs. In one embodiment, drug induced blood dyscrasias can be ameliorated by the methods and compositions provided herein.

Abstract: Neuropeptides are used to treat mammals who have been exposed to or who are suspected of having been exposed to spores of Bacillus anthracis. The treatment provides a dose-dependent protection from the lethal consequences of infections.

Abstract: Provided herein are methods and compositions for stimulating or promoting fibroblast proliferation. In one embodiment, provided herein are methods and compositions for promoting or enhancing wound healing.

Abstract: Myelodysplastic syndromes can be treated or ameliorated by the administration of substance P analogs as disclosed herein.

Abstract: Apparatus for measuring the filling level of a liquid in a container comprising a transmitting device 1 which emits ultrasound transmission pulses, a receiving device 2 which receives the echo signals reflected at the surface of the liquid and an evaluation device 8 which evaluates the transit times of the ultrasound transmission pulses and echo signals, wherein arranged at a given spacing relative to the transmitting/receiving device 1, is a reflector 3 which reflects the ultrasound transmission pulses in the direction of the surface of the liquid and also reflects the echo signals coming from the surface of the liquid in the direction of the receiving device 2.

Abstract: Wound healing is impaired in irradiated animals. Substance P and its active analogs promote wound healing in irradiated animals. Substance P and its analogs can be used to treat animals irradiated by a nuclear weapon, a nuclear accident, or a therapeutic regimen, for example. Wounds which are susceptible to such treatment include surgical wounds, weapons wounds, disease-caused wounds, bed sores, diabetic ulcers, etc.

Abstract: Hair pigment loss is treated by administration of Substance P or a bioactive analog thereof. The subject may have pigment loss in hair due to any of a variety of reasons, including drug side effects, genetic composition, aging, or nutritional deficit. The treatment can be conveniently administered topically. Maintenance or increasing the amount of hair color results from the treatments.

Abstract: Substance P or its analogs can be administered to humans to reverse or retard the course of various biological processes related to aging in adults. Reversal or retardation can be observed in hair color, muscle or joint pain, memory loss, sleep pattern, and visual accommodation.

Abstract: Substance P or its analogs are useful for treating and protecting against acute respiratory syndromes including ARDS and SARS. The active agents can be administered via inhalation therapy, intravenously, intramuscularly, sublingually, or by other methods. Disease indicia are reduced by substance P treatment.