Patents Assigned to Immunetech Pharmaceuticals
  • Pentapeptide synthesis
    Patent number: 5212287
    Abstract: A method of synthesizing commercial quantities of the pentapeptide L-aspartyl-L-seryl-L-aspartyl-L-prolyl-L-arginine, and salts or solvates thereof, e.g., the hydrochloride or acetate salt or water solvate, compounds useful in pharmaceutical compositions for the treatment of allergic conditions, is disclosed, as are novel intermediate compounds produced in the course of the synthesis.
    Type: Grant
    Filed: December 21, 1988
    Date of Patent: May 18, 1993
    Assignee: Immunetech Pharmaceuticals, Inc.
    Inventors: John C. Tolle, Wenying Z. Gifford, Kenneth W. Funk
  • Methods and compositions for the treatment of inflammatory bowel diseases and conditions
    Patent number: 5110795
    Abstract: Methods and compositions for the treatment of inflammatory bowel diseases, chemically-induced irritation and inflammation, and other irritative or inflammatory conditions utilizing the peptide sequences Asp-Ser-Asp-Pro-Arg, Asp-Ser-Asn-Pro-Arg, or derivatives or salts thereof are disclosed.
    Type: Grant
    Filed: January 26, 1990
    Date of Patent: May 5, 1992
    Assignee: Immunetech Pharmaceuticals
    Inventor: Gary S. Hahn
  • Methods and compositions for the treatment of non-IgE-mediated diseases
    Patent number: 5061692
    Abstract: Methods and compositions for the treatment of non-IgE-mediated inflammatory disease conditions utilizing the peptide Asp-Ser-Asp-Pro-Arg, or derivative thereof are disclosed.
    Type: Grant
    Filed: November 23, 1989
    Date of Patent: October 29, 1991
    Assignee: Immunetech Pharmaceuticals
    Inventor: Gary S. Hahn
  • Immunotherapeutic anti-inflammatory peptide agents
    Patent number: 4816449
    Abstract: Anti-inflammatory peptides of the formula A-B-C-D-E, useful in treating allergies, autoimmune diseases, and other disorders, and methods for using them are described.
    Type: Grant
    Filed: December 9, 1986
    Date of Patent: March 28, 1989
    Assignee: Immunetech Pharmaceuticals
    Inventor: Gary S. Hahn
  • Method of blocking immune complex binding to immunoglobulin Fc receptors
    Patent number: 4753927
    Abstract: A method of modulating immune responses in mammals by blocking immune complex binding to immunoglobulin Fc receptors is described, comprising administering a peptide comprising a portion selected from the amino acid sequence-Pro-Asp-Ala-Arg-His-Ser-Thr-Thr-Gln-Pro-Arg-Specific uses in reducing immune complex mediated inflammation or tissue destruction and in reducing the human allergic response are disclosed.
    Type: Grant
    Filed: January 21, 1986
    Date of Patent: June 28, 1988
    Assignee: Immunetech Pharmaceuticals
    Inventor: Gary S. Hahn
  • Method of blocking immune complex binding to immunoglobulin FC receptors
    Patent number: 4752601
    Abstract: A method of modulating immune complex mediated immune responses in mammals is described, comprising administering a peptide comprising the amino acid sequence-Thr-Ile-Ser-Lys-Ala-Lys-Gly-Gln-Pro-Arg-Specific uses in reducing immune complex mediated inflammation or tissue destruction and in modulating the proliferation or function of mononuclear cells are disclosed.
    Type: Grant
    Filed: April 1, 1986
    Date of Patent: June 21, 1988
    Assignee: Immunetech Pharmaceuticals
    Inventor: Gary S. Hahn
  • Peptide antagonists for the C5a anaphylatoxin
    Patent number: 4692511
    Abstract: Peptides and peptide compositions are disclosed which act as competitive antagonists for the C5a receptor and thus block inflammatory and immunomodulatory activity mediated by endogenous C5a.
    Type: Grant
    Filed: July 3, 1984
    Date of Patent: September 8, 1987
    Assignee: Immunetech Pharmaceuticals
    Inventor: Gary S. Hahn
  • Immunotherapeutic antiallergic polypeptide agents which bind to basophil immunoglobin Fc receptors
    Patent number: 4628045
    Abstract: A peptide having the amino acid sequence Asp-Ser-Glu-Pro-Arg and capable of blocking immune complex binding to immunoglobulin Fc receptors is disclosed.
    Type: Grant
    Filed: February 3, 1986
    Date of Patent: December 9, 1986
    Assignee: Immunetech Pharmaceuticals
    Inventor: Gary S. Hahn
  • Method of blocking immune complex binding to immunoglobulin Fc receptors
    Patent number: 4579840
    Abstract: Methods and peptides for blocking immunogloblin Fc receptors are set forth.
    Type: Grant
    Filed: August 12, 1983
    Date of Patent: April 1, 1986
    Assignee: Immunetech Pharmaceuticals
    Inventor: Gary S. Hahn