Abstract: The present invention relates to the anticancer property studies of a series of chiral palladium N-heterocyclic carbene complexes of the general formula of (NHC)2PdX2 [NHC=chiral N-heterocyclic carbene ligand 1-(1S,2S,5R/1R,2R,5S)-menthyl-4-(R)-1,2,4-triazol-5-ylidene, wherein R=Et, allyl and CH2Ph; X?Br or OCOCF3], as designated by, (1S,2S,5R)-(1-3)b and (1R,2R,5S)-(1-3)b, (1S,2S,5R)-(1, 3)c and (1R,2R,5S)-(1, 3)c represented by formula (Ig, Ih) below. The present invention further investigates the influence of chirality on the anticancer activity, wherein the enantiomeric pairs of present chiral palladium N-heterocyclic carbene complexes of formula (Ig, Ih) shows no differential activity based on optical isomerism despite all of the palladium complexes exhibiting high anti-proliferative activity towards a variety of cancer cells.

Abstract: The present disclosure includes a spray bottle assembly (100) which provides separate compartments for containing two or more constituents of a formulation, thereby, preventing premixing of the constituents before the first use, hence, increasing shelf life in a hassle-free way. The spray bottle assembly (100) comprises a spray head (200) for discharging the constituents of a formulation stored in the spray bottle assembly (100), a container bottle (300) for storing a passive constituent of the formulation; a storage receptacle (400) coupled with the container bottle (300), wherein said storage receptacle (400) facilitates the storage of an active constituent of the formulation isolated from the passive constituent; and a dispensing means (500) integrated with the storage receptacle (400).

Abstract: According to the invention, there is provided a frequency to voltage converter for generating an output voltage proportional to the frequency of input signal. It comprises a switched capacitor circuit for receiving input signal and generating an input current proportional to said frequency, the switched capacitor having a capacitor charging and discharging at said frequency; an operational transconductance amplifier (OTA) for receiving at least one control voltage representative of the input current and generating current proportional to the at least one control voltage; at least one negative feedback circuit connecting input and output of the OTA, each negative feedback circuit comprising: a control transistor coupled to a node of the OTA; a diode connected transistor coupled to the control transistor for sensing current flowing through the control transistor; and a feedback transistor coupled to another node of the OTA.

Abstract: A transmission system comprising two degrees-of-freedom compound planetary gear train with two conjoined planetary gear trains and four torque-transfer devices. The different combinations of states of various torque-transfer devices yield multiple modes of operation. The planetary gear train allows the addition of power of two prime-movers to drive the load. Additionally, the transmission system can split the power from one prime-mover into requirements of the energy storage system while catering to the output needs. This limits the re-circulating power to a fraction of the input power. Other advantage of the transmission is that it provides a high overdrive ratio, which permits regeneration even at moderate speeds. The transmission obviates the need for a torque converter. The transmission can operate as multi-speed, fully automatic.