Patents Assigned to Indication BioScience LLC
  • Compositions and methods using a cannabinoid to enhance bioavailability of a statin
    Patent number: 11786482
    Abstract: The invention relates to pharmaceutical compositions comprising a statin and a cannabinoid, and their use for the treatment of hypercholesterolemia and atherosclerosis. It has been found that compositions combining a statin and a cannabinoid are improved over existing statin formulations. The compositions of the invention for example allow for a lower effective dose of statin and a reduction of the adverse effects seen with statins taken alone. Dosing ranges and formulations suitable for oral, buccal, and sublingual administration are disclosed. Various specific cannabinoids such as cannabidiol and synthetic cannabidiols selected for their anti-inflammatory, antioxidant, and anti-atherosclerotic effect are shown to be particularly advantageous.
    Type: Grant
    Filed: January 3, 2022
    Date of Patent: October 17, 2023
    Assignee: Indication BioScience LLC
    Inventors: James Smeeding, Mathew Sherwood
  • Pharmaceutical compositions comprising a statin and a cannabinoid and uses thereof
    Patent number: 11234944
    Abstract: The invention relates to pharmaceutical compositions comprising a statin and a cannabinoid, and their use for the treatment of hypercholesterolemia and atherosclerosis. It has been found that compositions combining a statin and a cannabinoid are improved over existing statin formulations. The compositions of the invention for example allow for a lower effective dose of statin and a reduction of the adverse effects seen with statins taken alone. Dosing ranges and formulations suitable for oral, buccal, and sublingual administration are disclosed. Various specific cannabinoids such as cannabidiol and synthetic cannabidiols selected for their anti-inflammatory, antioxidant, and anti-atherosclerotic effect are shown to be particularly advantageous.
    Type: Grant
    Filed: October 20, 2020
    Date of Patent: February 1, 2022
    Assignee: Indication BioScience LLC
    Inventors: James Smeeding, Mathew Sherwood
  • Pharmaceutical compositions comprising a statin and a cannabinoid and uses thereof
    Patent number: 10835501
    Abstract: The invention relates to pharmaceutical compositions comprising a statin and a cannabinoid, and their use for the treatment of hypercholesterolemia and atherosclerosis. It has been found that compositions combining a statin and a cannabinoid are improved over existing statin formulations. The compositions of the invention for example allow for a lower effective dose of statin and a reduction of the adverse effects seen with statins taken alone. Dosing ranges and formulations suitable for oral, buccal, and sublingual administration are disclosed. Various specific cannabinoids such as cannabidiol and synthetic cannabidiols selected for their anti-inflammatory, antioxidant, and anti-atherosclerotic effect are shown to be particularly advantageous.
    Type: Grant
    Filed: October 1, 2017
    Date of Patent: November 17, 2020
    Assignee: Indication BioScience LLC
    Inventors: James Smeeding, Mathew Sherwood