Patents Assigned to Indicator Systems International
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Patent number: 11480577Abstract: Disclosed are methods for detecting remnant cancer cells in a tissue sample.Type: GrantFiled: January 10, 2020Date of Patent: October 25, 2022Assignee: INDICATOR SYSTEMS INTERNATIONAL, INC.Inventors: Gerald F. Swiss, John V. Fante, Robert M. Moriarty, Richard J. Pariza
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Patent number: 10753942Abstract: Disclosed methods for detecting remnant cancer cells in a tissue sample.Type: GrantFiled: October 3, 2018Date of Patent: August 25, 2020Assignee: Indicator Systems International, Inc.Inventors: Robert M. Moriarty, Richard J. Pariza, David M. White, Gerald F. Swiss
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Patent number: 10539567Abstract: Disclosed are methods for detecting remnant cancer cells in a tissue sample.Type: GrantFiled: May 15, 2017Date of Patent: January 21, 2020Assignee: Indicator Systems International, Inc.Inventors: Gerald F. Swiss, John V. Fante, Robert M. Moriarty, Richard J. Pariza
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Publication number: 20190107543Abstract: Disclosed methods for detecting remnant cancer cells in a tissue sample.Type: ApplicationFiled: October 3, 2018Publication date: April 11, 2019Applicant: INDICATOR SYSTEMS INTERNATIONAL, INC.Inventors: Robert M. MORIARTY, Richard J. PARIZA, David M. WHITE, Gerald F. Swiss
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Patent number: 10239891Abstract: Disclosed are compounds, compositions and methods for detecting remnant cancer cells in a tissue sample.Type: GrantFiled: May 15, 2017Date of Patent: March 26, 2019Assignee: Indicator Systems International, Inc.Inventors: Gerald F. Swiss, Richard J. Pariza, Robert M. Moriarty
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Patent number: 9926334Abstract: Disclosed are compounds, compositions and methods for detecting remnant cancer cells in a tissue sample.Type: GrantFiled: May 15, 2017Date of Patent: March 27, 2018Assignee: Indicator Systems International, Inc.Inventors: Gerald F. Swiss, Richard J. Pariza, Robert M. Moriarty
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Publication number: 20170128595Abstract: Provided herein are medical devices capable of self-reporting microbial growth adjacent the site of the implanted device.Type: ApplicationFiled: June 22, 2015Publication date: May 11, 2017Applicant: Indicator Systems International, Inc.Inventors: Gerald F. Swiss, Robert M. Moriarty, Ram W. Sabnis
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Patent number: 9115066Abstract: Provided herein are trisubstituted methyl alcohols, preferably pH indicators that are substituted with optionally substituted aryl and or optionally substituted heteroaryl groups, and optionally include one or more polymerizable substituents.Type: GrantFiled: December 14, 2012Date of Patent: August 25, 2015Assignee: Indicator Systems International, Inc.Inventors: Gerald F. Swiss, Photon Rao, Ram W. Sabnis
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Patent number: 8979260Abstract: This invention relates to contact lenses comprising pH indicating moieties useful for determining the presence or absence of active bacterial infections wherein said pH indicator is entrapped in the lens. Other aspects relate to contact lenses comprising pH indicating moieties useful for determining the presence or absence of active bacterial infections and a biodegradable coating with a biocompatible colorant entrapped within the coating useful for determining the usable lifespan of the contact lens. Other aspects relate to methods of using such contact lenses.Type: GrantFiled: October 12, 2012Date of Patent: March 17, 2015Assignee: Indicator Systems International, Inc.Inventor: Craig Keshishian
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Patent number: 8871464Abstract: An apparatus and method are provided for visually monitoring, detecting, and/or determining the presence, absence, and/or growth of harmful or potentially harmful bacterial microorganisms beneath a wound dressing, in one example used to cover an indwelling central venous catheter or other catheter. A bacteria detection apparatus includes a barrier membrane, a permeable membrane for placement proximate a wound or a catheter insertion site, and an indicator between the barrier membrane and the permeable membrane for indicating the presence of bacteria proximate the permeable membrane. A method of using a bacterial growth detection apparatus is also provided.Type: GrantFiled: March 21, 2012Date of Patent: October 28, 2014Assignee: Indicator Systems InternationalInventor: Jon Booher
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Patent number: 8637271Abstract: Polymeric indicators are provided for visually monitoring, detecting, and/or determining the presence of metabolic byproducts from harmful or potentially harmful microorganisms.Type: GrantFiled: November 5, 2008Date of Patent: January 28, 2014Assignee: Indicator Systems International, Inc.Inventors: Jon Booher, Joel R. Gorski
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Patent number: 8609355Abstract: Methods, devices, and kits are provided herein for the accurate and rapid detection of disease causing microbes in a sample by the detection of microbial components of which correlate to the presence of the microbe. Kits include a first binding agent operatively coupled to an immobilized support; and a second binding agent operatively coupled to one or more pH indicating moieties wherein the first and second binding agents bind with sufficient specificity to the microbial component to permit detection of that component which correlates to the presence of the microbe in the sample.Type: GrantFiled: July 25, 2012Date of Patent: December 17, 2013Assignee: Indicator Systems International, Inc.Inventors: Gerald F. Swiss, Laurie B. F. Stellman
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Publication number: 20130197262Abstract: Provided herein are trisubstituted methyl alcohols, preferably pH indicators that are substituted with optionally substituted aryl and or optionally substituted heteroaryl groups, and optionally include one or more polymerizable substituents.Type: ApplicationFiled: December 14, 2012Publication date: August 1, 2013Applicant: Indicator Systems International, Inc.Inventor: Indicator Systems International, Inc.
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Patent number: 8425996Abstract: Polymeric indicator films and pH indicating wraps are provided for visually monitoring, detecting, and/or determining the presence of metabolic byproducts from harmful or potentially harmful microorganisms. Also provided are methods of use and preparation of the polymeric indicator films.Type: GrantFiled: January 25, 2010Date of Patent: April 23, 2013Assignee: Indicator Systems International, Inc.Inventors: Joel R. Gorski, Jon Booher, Ram W. Sabnis
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Patent number: 8153394Abstract: An apparatus and method are provided for visually monitoring, detecting, and/or determining the presence, absence, and/or growth of harmful or potentially harmful bacterial microorganisms beneath a wound dressing, in one example used to cover an indwelling central venous catheter or other catheter. A bacteria detection apparatus includes a barrier membrane, a permeable membrane for placement proximate a wound or a catheter insertion site, and an indicator between the barrier membrane and the permeable membrane for indicating the presence of bacteria proximate the permeable membrane. A method of using a bacterial growth detection apparatus is also provided.Type: GrantFiled: May 5, 2010Date of Patent: April 10, 2012Assignee: Indicator Systems InternationalInventor: Jon Booher
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Patent number: 7749531Abstract: An apparatus and method are provided for visually monitoring, detecting, and/or determining the presence, absence, and/or growth of harmful or potentially harmful bacterial microorganisms beneath a wound dressing, in one example used to cover an indwelling central venous catheter or other catheter. A bacteria detection apparatus includes a barrier membrane, a permeable membrane for placement proximate a wound or a catheter insertion site, and an indicator between the barrier membrane and the permeable membrane for indicating the presence of bacteria proximate the permeable membrane. A method of using a bacterial growth detection apparatus is also provided.Type: GrantFiled: June 8, 2005Date of Patent: July 6, 2010Assignee: Indicator Systems InternationalInventor: Jon Booher