Abstract: The present invention relates to an anti-tenascin C peptide aptamer having a specific amino acid sequence and a diagnosis kit comprising it. The anti-tenascin C peptide aptamer of the instant invention shows a predominant clearance rate due to its small molecular weight as well as specific binding affinity to tenascin C, having excellent advantages in in vivo or ex vivo tumor imaging.
Type:
Grant
Filed:
July 31, 2013
Date of Patent:
April 28, 2015
Assignee:
Industry-Academy Cooperation Foundation, Dankook University
Inventors:
Sun Joo Jeong, Mee Young Kim, Ok Ran Kim, Heui Ran Lee, Kee Rang Park
Abstract: The present invention relates to an anti-tenascin C peptide aptamer having a specific amino acid sequence and a diagnosis kit comprising it. The anti-tenascin C peptide aptamer of the instant invention shows a predominant clearance rate due to its small molecular weight as well as specific binding affinity to tenascin C, having excellent advantages in in vivo or ex vivo tumor imaging.
Type:
Application
Filed:
August 22, 2008
Publication date:
October 7, 2010
Applicant:
Industry-Academy Cooperation Foundation Dankook University
Inventors:
Sun Joo Jeong, Mee Young Kim, Ok Ran Kim, Heui Ran Lee, Kee Rang Park