Abstract: The present invention relates to a molecular marker, a specific primer pair, and an identification method of the high-quality Ganoderma lucidum strain HMGIM-M624. The high-quality Ganoderma lucidum strain HMGIM-M624 was preserved in Guangdong Microbial Culture Collection Center (address: 5th Floor, No. 59 Building of No. 100 Yard, Mid. Xianlie Road, Guangzhou City) with the preservation number of GDMCC No: 60889 on Nov. 7, 2019. The molecular marker is an InDel molecular marker. The high-quality Ganoderma lucidum strain HMGIM-M624 has a base deletion of CATGCTGTA at the 246451th-246460th site of the chromosome sca34. The present invention provides reagents for detecting the molecular marker of the high-quality Ganoderma lucidum strain HMGIM-M624. The reagents can distinguish the high-quality Ganoderma lucidum strain HMGIM-M624 from the other 11 G. lucidum strains for commercial cultivation, thus specifically identifying the high-quality Ganoderma lucidum strain HMGIM-M624.

Abstract: Herbal composition having an effect of reducing uric acid, which is made from the following herbal materials in specified portions by weight: 4-30 portions of Glabrous greenbrier rhizome, 2-15 portions of Chicory, 2-15 portions of Herba Plantaginis, 2-20 portions of Coix seed, and 2-10 portions of Kudzuvine Root. The composition may be used in combination with modern Western medicines to achieve optimal effects.

Abstract: The invention relates to the field of health food technologies, and particularly to a composition and an application thereof in preparing a product for protecting mitochondria. The invention provides a composition, the raw materials of which include Haematococcus pluvialis, Lycium ruthenicum, Cordyceps militaris and nicotinamide. The composition has the effects of improving an oxidative stress level under a mitochondrial dysfunction and delaying mitochondrion-related aging. Compared with a single constituent, constituents in the composition cooperate with each other to produce a synergistic effect, which significantly improves an effect of protecting a mitochondrial function.

Abstract: A Chinese herbal medicine composition for improving hearing impairment comprises at least two of avocado extract, ecklonia cava extract and perilla extract. The Chinese herbal medicine composition can effectively reduce a NO content secreted by cells, reduce an inflammatory reaction of cells, and have a good effect of improving LPS-induced hearing loss. Moreover, ingredients of the Chinese herbal medicine composition are medicine-and-food homologous ingredients, which have no obvious cytotoxicity and obvious side effects.

Abstract: The invention discloses a Chinese herbal medicine composition for relieving hearing loss and a preparation method and use thereof. The Chinese herbal medicine composition is prepared from at least two of the medicinal and edible raw materials of rhizoma curcumae longae, Dendrobium nobile and fructus Piperis longi, can effectively reduce the content of NO secreted by cells, reduces cell inflammation, and has a good effect of relieving hearing loss induced by LPS. The Chinese herbal medicine composition is not a simple combination of traditional Chinese medicines and has a synergistic effect. The Chinese herbal medicine composition can significantly reduce ABR value, MDA, and glutamic acid of a patient with hearing loss, significantly relieves hearing loss, and can be developed into functional foods and medicines for relieving hearing loss as an active ingredient.

Abstract: The present invention relates to a composition having an anti-glycation effect and an application thereof. The anti-glycation composition includes the following constituents in parts by mass: 0.1 to 5 parts of Osmanthus fragrans extract, 0.1 to 5 parts of Punica granatum extract and 0.1 to 2 part of Olea europaea extract, wherein in the Osmanthus fragrans extract, a mass content of polyphenol is more than or equal to 10%, and a mass content of verbascoside is more than or equal to 10%; in the Punica granatum extract, a mass content of polyphenol is more than or equal to 30%, and a mass content of punicalagin is more than or equal to 8%; and in the Olea europaea extract, a mass content of polyphenol is more than or equal to 10%, and a mass content of hydroxytyrosol is more than or equal to 3%.

Abstract: The present disclosure relates to the field of microbial technology, and discloses a composite probiotics and the use thereof. The composite probiotics in the present disclosure is consisted of Bifidobacterium adolescentis CCFM8630, Lactobacillus reuteri CCFM8631, Lactobacillus rhamnosus CCFM1044 and Lactobacillus casei CCFM711, whose effect of alleviating metabolic syndrome is significantly better than that of CCFM8630 or CCFM8631 alone or combination of the two, especially in aspects of lowering contents of serum low density lipoprotein, total cholesterol, and liver triglyceride and contents of serum alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and IFN-?, and increasing contents of liver glutathione and superoxide dismutase, etc. The extent of decrease or increase is increased by 7.91% to 837.31% compared with the formulations of CCFM8630 or CCFM8631 alone or combination of the two probiotics. The combination of the four probiotics can achieve a significant synergistic effect.

Abstract: The present invention provides a solid mask and a preparation method thereof. The solid mask includes a hydrophobic substrate layer and a nanofiber layer, the nanofiber layer has a three-dimensional structure and is electro-spun onto the hydrophobic substrate layer through uniaxial electrostatic spinning technology, and the nanofiber layer is prepared by the following food-grade raw materials in parts by mass: 10 to 30 parts of gelatin, 1 to 30 parts of soya bean lecithin and 0.1 to 10 parts of a functional substance. The present invention provides a solid mask, using gelatin and soya bean lecithin as the framework. The nanofiber layer is a three-dimensional laminate made of fibers having a diameter of a few hundred nanometers. The nanofiber layer has a membrane structure similar to the extracellular matrix. The raw materials of the solid mask are all food-grade raw materials or natural extracts.

Abstract: The present disclosure relates to the field of microbial technology, and discloses a probiotic composition and use thereof. The probiotic composition in the present disclosure is consisted of Bifidobacterium adolescentis CCFM8630, Lactobacillus reuteri CCFM8631 and Lactobacillus rhamnosus CCFM1044, whose effect of alleviating metabolic syndrome is significantly better than that of CCFM8630 or CCFM8631 alone or combination of the two, especially in aspects of lowering epididymal fat content, lowering fasting blood glucose level, lowering the area under sugar tolerance curve and lowering contents of serum low density lipoprotein and total cholesterol, improving liver antioxidant capacity and lowering serum IL-1? content, etc. The extent of decrease or increase is increased by 9.62% to 769.62% compared with formulations of a single probiotic or a combination of two probiotics. The combination of three probiotics achieves a significant synergistic effect.

Abstract: The present invention relates to the field of health care food technology, specifically to a traditional Chinese medicine composition with a function of protecting joints, a use thereof, a method for producing the same and a health care food thereof. The Chinese medicine composition comprises CURCUMAE LONGAE RHIZOMA extract, cartilage extract, COICIS SEMEN extract and PUERARIAE LOBATAE RADIX extract. The composition of the present disclosure has a reasonable formulation, and the ingredients cooperate with each other to achieve functions of reducing arthrocele degree, decreasing arthritis index, ameliorating biochemical index of arthritis and reducing articular cavity area through various paths and at various levels.

Abstract: Provided is a method of producing an oil containing polyunsaturated fatty acids by using Schizochytrium sp. The method comprises: performing fermentation using Schizochytrium sp.; resuspending the resultant cells after fermentation in water, adding cellulase and neutral protease for enzymolysis; mixing the enzymatic hydrolyzate with n-hexane, shaking, extracting, centrifuging, and collecting the n-hexane phase; concentrating the n-hexane phase under reduced pressure to remove the n-hexane, and drying to obtain an oil; performing a first crystallization and a second crystallization, and then performing cold filtration to obtain a liquid oil after the second crystallization; and subjecting the liquid oil to deacidification and decolorization. By regulating fermentation conditions and conducting concentration processing on polyunsaturated fatty acids, the content of eicosapentaenoic acid in the Schizochytrium sp.

Abstract: The present disclosure relates to the technical field of traditional Chinese medicine technology, especially to a composition, a preparation method thereof and an application in the prevention and treatment of mammary gland diseases. The present disclosure provides a composition consisting of Rehmanniae Radix Praeparata, Lycii Fructus, Polygonati Rhizoma, Radix Codonopsis Pilosulae, Paeoniae Radix Alba, Cyperi Rhizoma (processed with vinegar) and Grape Seed. The composition has functions of improving hyperplasia of mammary gland and/or anti-oxidation. Compared with each control group, the composition provided by the present disclosure has the optimal effects, and the effect has statistical differences, indicating that the components in the composition provided by the present disclosure are reasonably arranged and can play a good synergistic effect. Furthermore, the preparation is safe and has no side effects.

Abstract: The present invention provides a solid mask and a preparation method thereof. The solid mask includes a hydrophobic substrate layer and a nanofiber layer, the nanofiber layer has a three-dimensional structure and is electro-spun onto the hydrophobic substrate layer through uniaxial electrostatic spinning technology, and the nanofiber layer is prepared by the following food-grade raw materials in parts by mass: 10 to 30 parts of gelatin, 1 to 30 parts of soya bean lecithin and 0.1 to 10 parts of a functional substance. The present invention provides a solid mask, using gelatin and soya bean lecithin as the framework. The nanofiber layer is a three-dimensional laminate made of fibers having a diameter of a few hundred nanometers. The nanofiber layer has a membrane structure similar to the extracellular matrix. The raw materials of the solid mask are all food-grade raw materials or natural extracts.

Abstract: The present disclosure relates to the field of drugs and health foods. Disclosed is a traditional Chinese medicine composition comprising Lycii fructus polysaccharide, Polygonati rhizoma polysaccharide, Caryophylli flos oil and Cinnamomi cortex oil. Experiments show that the traditional Chinese medicine composition has a scientific formulation, synergistic functions, without toxic and side effects, and not only has nutritional value but also inhibits the growth of tumor. Comparing with individual components, the composition significantly increases the percentages of CD4+ and CD8+ cells in lymphocytes of the tumor stroma, increases body immune function, recovers normal immune surveillance function, decreases the expression rate of VEGF and TGF-? 1 positive cells in tumor tissue, assists in treating tumor, increases antitumor effects of chemotherapy drugs, improves immune status of body, has the function of restoring normal immune surveillance, preventing and assisting in treating tumor.

Abstract: A skin whitening program, comprising an external application step, a treatment step and an oral administration step. A skin care product for external application is selected from a whitening, brightening or yellow-removing skin care product, the effective ingredient in the skin care product being selected from a tricholoma matsutake, carthamus tinctorius or rhodiola rosea extract, a tricholoma matsutake, glycyrrhiza uralensis or pearl extract, or a panax notoginseng, salvia miltiorrhiza or radix astragali extract. A beautifying device for treatment is selected from an iontophoresis, microcurrent or LED green light beautifying device.

Abstract: The present invention relates to a composition having an anti-glycation effect and an application thereof. The anti-glycation composition includes the following constituents in parts by mass: 0.1 to 5 parts of Osmanthus fragrans extract, 0.1 to 5 parts of Punica granatum extract and 0.1 to 2 part of Olea europaea extract, wherein in the Osmanthus fragrans extract, a mass content of polyphenol is more than or equal to 10%, and a mass content of verbascoside is more than or equal to 10%; in the Punica granatum extract, a mass content of polyphenol is more than or equal to 30%, and a mass content of punicalagin is more than or equal to 8%; and in the Olea europaea extract, a mass content of polyphenol is more than or equal to 10%, and a mass content of hydroxytyrosol is more than or equal to 3%.

Abstract: The present disclosure relates to the field of drugs and health foods. Disclosed is a traditional Chinese medicine composition comprising GANODERMA polysaccharide, MORINDAE OFFICINALIS RADIX polysaccharide, POLYGONATI RHIZOMA polysaccharide, ANGELICAE SINENSIS RADIX oil and MYRISTICAE SEMEN oil. Experiments show that the traditional Chinese medicine composition has a scientific formulation, synergistic functions, without toxic and side effects, and not only has nutritional value but also inhibits the growth of tumor. Comparing with individual components, the composition significantly increases the percentages of CD4+ and CD8+ cells in lymphocytes of the tumor stroma, enhances body immune function, restores normal immune surveillance function, decreases VEGF and TGF-?1 positive cells in tumor tissue, assists in treating tumor, increases antitumor effects of chemotherapy drugs, improves immune status of body, has the function of restoring normal immune surveillance, preventing and assisting in treating tumor.

Abstract: Provided is a strain CCFM8631 of Lactobacillus reuteri and use thereof. The strain CCFM8631 of Lactobacillus reuteri can significantly increase neurotransmitter 5-hydroxytryptamine level in peripheral blood, recover the hormone levels, for example testosterone and so on in peripheral blood of rat, normalize abnormal abundances of Blautia genus and Turicibacter genus, Oscillospira genus and Bifidobacterium genus in intestinal flora of rat affected by high-fat high-starch diet, show good tolerance to simulated gastrointestinal fluid and quickly colonize in intestinal, significantly improve pathological damages of tissues such as liver, duodenum and so on, and increase triglyceride and total cholesterol levels in serum and oral glucose tolerance of rat with metabolic syndrome caused by high-fat high-starch diet.

Abstract: The present disclosure relates to the field of drugs and health foods. Disclosed is a traditional Chinese medicine composition comprising GANODERMA polysaccharide, GRIFOLA FRONDOSA polysaccharide, ANGELICAE SINENSIS RADIX oil and CINNAMOMI CORTEX oil. Experiments show that the traditional Chinese medicine composition has a scientific formulation, synergistic functions, without toxic and side effects, and not only has nutritional value but also inhibits the growth of tumor. Comparing with individual components, the composition significantly increases the percentages of CD4+ and CD8+ cells in lymphocytes of the tumor stroma, increases body immune function, recovers normal immune surveillance function, decreases the expression rate of VEGF and TGF-? 1 positive cells in tumor tissue, assists in treating tumor, increases antitumor effects of chemotherapy drugs, improves immune status of body, has the function of restoring normal immune surveillance, preventing and assisting in treating tumor.

Abstract: The present disclosure relates to the field of health care products, disclosing a powder made from inulin, FOLIUM CYCLOCARYA PALIURUS, RHIZOMA DIOSCOREA OPPOSITE, RADIX ASTRAGALUS MEMBRANACEUS, CAULIS DENDROBIUM and RADIX ET RHIZOMA SALVIA MILTIORRHIZA. The raw materials of the powder are all from natural Chinese herbal medicine without addition of excipient. In addition, dosage required for the powder is small; it can be directly dissolved in water for taking; it is soluble in cold water and can be absorbed quickly. The method for preparing the powder in the present disclosure is simple and suitable for large-scale production. Also, it is easy to be carried. The powder obtained has a good stability and long storage time. Experiments show that the powder of the present disclosure has greatly hypoglycemic and hypolipidemic effects, therefore can be used to prepare the health care foods having hypoglycemic and hypolipidemic effect.