Abstract: Concentric flow focusing encapsulation devices and methods for production of microencapsulated droplets of a first core material surrounded by a second shell material include assessment of non-dimensional fluid dynamic parameters that are related to the characteristics of produced droplets. The parameters are specifically related to characteristics such as homogenous or non-homogenous modes of concentric droplet breakup, density distribution of various droplet sizes, and qualities such as monodispersity of droplets produced. By identifying control parameters in specific regions, control variables may be selected to produce droplets or particles with desired qualities.