Abstract: The present invention pertains to certain imidazo[4,5-b]pyridin-2-one and oxazolo[4,5-b]pyridin-2-one compounds and analogs thereof, which, inter alia, inhibit RAF (e.g., B-RAF) activity, inhibit cell proliferation, treat cancer, etc.
Type:
Application
Filed:
October 21, 2005
Publication date:
December 13, 2007
Applicants:
CANCER RESEARCH TECHNOLOGY LIMITED, INSTITUE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (THE), ASTEX THERAPEUTICS LIMITED
Inventors:
Dan Niculescu-Duvaz, Caroline Springer, Adrian Gill, Richard Taylor, Richard Marais, Hermen Dijkstra, Catherine Gaulon, Delphine Menard, Esteban Roman Vela