Abstract: Method for examining a multiplicity of distributed objects (1) by using an overview image (200) of the area (2) in which the objects (1) are distributed, wherein the overview image (200) is converted (110) into a binary image (210) by virtue of the intensity values (202) of the pixels (201) of the overview image (200) being classified (202a, 202b) as to whether they are on the near or far side of a prescribed threshold (208); the binary image (210) is cleared (120) of structures (219) that are smaller than the objects (1), so that a cleared image (220) is produced; and the cleared image (220) is morphologically closed (130), so that a binary object mask (230) is produced that indicates which locations in the area (2) belong to objects (1) and which locations in the area (2) do not belong to an object.

Abstract: An exemplary laser microscope can be provided, comprising at least one first laser source which emits at least one (e.g., pulsed) excitation beam, a scanning optical configuration (e.g., configured to scan the excitation beam over the surface of a sample), a focusing optical configuration (e.g., configured to focus the excitation beam onto the sample), and at least one detector configured to detect light emitted by the sample due to an optical effect in response to the excitation beam. A second laser source facilitates a pulsed ablation beam for a local ablation of the material of the sample. The ablation beam can be guided to the sample via the scanning and focusing optical configurations. The first and second laser sources can be fed by a mutual continuous wave pump laser and/or a mutual pulsed pump laser. The first laser source can emit pulses with at least two different wavelengths.

Abstract: The invention relates to an apparatus for generating laser pulses. It is an object of the invention to provide a method for generating synchronized laser pulse trains at variable wavelengths (e.g., for coherent Raman spectroscopy/microscopy), wherein the switching time for switching between different wavelengths should be in the sub-?s range. For this purpose the apparatus according to the invention comprises a pump laser (1), which emits pulsed laser radiation at a specified wavelength, an FDML laser (3), which emits continuous wave laser radiation at a cyclically variable wavelength, and a nonlinear conversion medium (4), in which the pulsed laser radiation of the pump laser (1) and the continuous wave laser radiation of the FDML laser (3) are superposed.

Abstract: Exemplary methods can be provided for the determination of a microbial pathogen. In addition, exemplary methods can be provided for the determination of a microbial pathogen and its anti-infective resistance. Further, an exemplary method can be provided for determining a bacterium and its antibiotic resistance. Systems and computer-accessible media can be provided for the determination of a microbial pathogen and its anti-infective resistance.

Abstract: Exemplary method, computer-accessible medium and system can be provided for determining the presence or absence of a local and/or global property of a biological tissue sample. Thus, it is possible to obtain at least one image of the sample, search the image(s) for a presence of at least one particular feature that is contained in a pre-defined set of features, and assign, to the particular feature(s). It is possible to compute, with a computer processor, at least one discriminant value that is a function of the pronunciation index that is weighted with a particular weight. The weight of each pronunciation index is a measure for a relevance of the corresponding feature with respect to the property. It is possible to determine whether the property is present in at least one part of the biological tissue sample depending on whether the discriminant value exceeds a pre-defined threshold and/or and optimized threshold.

Abstract: An arrangement for testing an elongated body 1 or a welded and bonded joint in the body for faults 60 has a device 4, 5 for production of an eddy current in the elongated body 1 or its welded and bonded joint. At least one magnetic field sensor 7 for sensing the magnetic field is provided on the elongated body 1 or the welded and bonded joint. The dimensions of the at least one magnetic field sensor 7 are equal to or less than the fault 60 to be investigated.