Patents Assigned to Institut Suisse de Recherche Experimentale sur le Cancer
  • Hydroxyapatite-antigen conjugates and methods for generating a poly-Ig immune response
    Patent number: 6541000
    Abstract: A method for generating antigen-sensitized Ig-A-producing lymphoblasts in a mammal, using an immunogen comprising an antigen or antigen mixture in association with hydroxylated calcium phosphate (hydroxy apatite) is administered to a mucosal surface of the mammal.
    Type: Grant
    Filed: January 16, 1998
    Date of Patent: April 1, 2003
    Assignees: President & Fellows of Harvard College, Institut Suisse de Recherche Experimentale sur le Cancer
    Inventors: Helen M. Amerongen, Marian R. Neutra, Jean-Pierre Kraehenbuhl