Abstract: A ventricular cannulation device. An inner part is placed in the cardiac chamber and an outer part is placed outside the cardiac wall. Each of the inner and outer parts is equipped with means for catching onto the cardiac wall. The inner part bears a means for guiding and attaching the outer part thereto. A tube corresponding to the opening of the cardiac wall serves as a support for an outer tube or a vascular prosthesis. A blood circulatory assistance system is provided using a bio-pump, made from the patient's muscle, and a pulse generator to stimulate the bio-pump under program control, to pump blood from the ventricle. Vascular prosthesis are used to connect the cannulation device and the bio-pump with the aorta for blood flow therethrough.