Patents Assigned to Institute for Cancer Research d/b/a The Research Center of Fox Chase Cancer (Fox Chase Cancer
  • METHODS FOR SCREENING COMPOUNDS FOR CAPABILITY TO INHIBIT PREMALIGNANT SQUAMOUS EPITHELIAL CELL PROGRESSION TO A MALIGNANT STATE
    Publication number: 20130217594
    Abstract: Methods for screening compounds for their capability to inhibit CYP1B1-mediated proliferation and motility of and/or to reverse estrogen-induced reduction in apoptosis of premalignant or malignant cells are provided. Kits for practicing the screening methods are also provided.
    Type: Application
    Filed: October 28, 2011
    Publication date: August 22, 2013
    Applicant: Institute for Cancer Research d/b/a The Research Center of Fox Chase Cancer (Fox Chase Cancer
    Inventors: Margie Clapper, Ekaterina Shatalova