Patents Assigned to Institute National de la Sante & de la Recherche Medicale (INSERM)
  • Live Attenuated Bordetella Strains as a Single Dose Vaccine Against Whooping cough
    Publication number: 20090246222
    Abstract: A mutated Bordetella strain comprising at least a mutated ptx gene, a deleted or mutated dnt gene and a heterologous ampG gene is provided. The attenuated mutated Bordetella strain can be used in an immunogenic composition or a vaccine for the treatment or prevention of a Bordetella infection. Use of the attenuated Bordetella strain for the manufacture of a vaccine or immunogenic composition, as well as methods for protecting mammals against infection by Bordetella are also provided.
    Type: Application
    Filed: March 7, 2007
    Publication date: October 1, 2009
    Applicants: Institute Pasteur de Lille, Institute National de la Sante de la Recherche Medicale (Inserm)
    Inventors: Camille Locht, Nathalie Mielcarek, Anne-Sophie Debrie, Dominique Raze, Julie Bertout
  • Method of arresting degeneration of the substantia nigra by high frequency stimulation of subthalamic nucleus
    Patent number: 5707396
    Abstract: A method of preventing further degeneration of the substantia nigra observed in patients with Parkinson's disease.
    Type: Grant
    Filed: April 25, 1996
    Date of Patent: January 13, 1998
    Assignee: Institute National de la Sante de la Recherche Medicale (INSERM)
    Inventor: Alim Benabid
  • Polypeptide possessing thymic activity
    Patent number: 4148886
    Abstract: The novel thymic factor polypeptide hormone, elaborated by the thymus and und in the blood serum, is isolated. The hormone is useful for the treatment of autoimmune diseases and for selectively stimulating T-cell activity in aging subjects.
    Type: Grant
    Filed: April 25, 1978
    Date of Patent: April 10, 1979
    Assignee: Institute National de la Sante & de la Recherche Medicale (INSERM)
    Inventors: Jean-Francois Bach, Jean Hamburger