Patents Assigned to INSTYTUT BIOCHEMII I BIOFIZYKI POLSKIEJ AKADEMII NAUK
  • PEPTIDE FOR USE IN THE TREATMENT OR PREVENTION OF COVID-19
    Publication number: 20240082341
    Abstract: Improved peptides suitable for blocking the interaction between SARS-COV-2 virus S glycoprotein and the human ACE2 receptor are disclosed, in particular for the treatment or to assist the treatment of an infection caused by SARS-CoV-2 virus and/or viruses with high genome sequence similarity to the SARS-CoV-2 virus.
    Type: Application
    Filed: December 28, 2021
    Publication date: March 14, 2024
    Applicant: Instytut Biochemii I Biofizyki Polskiej Akademii Nauk
    Inventors: Norbert ODOLCZYK, Piotr ZIELENKIEWICZ, Maria WINIEWSKA-SZAJEWSKA, Jaroslaw POZNANSKI, Urszula ZIELENKIEWICZ, Joanna KLIM
  • Methods for diagnosis, differentiation and monitoring using urine proteins as markers in IgA nephropathy
    Patent number: 11029314
    Abstract: A method for diagnosis of IgA nephropathy is provided using a combination of alpha-1B-glycoprotein (A1BG) or a truncated fragment thereof having a molecular weight of 13-60 kDa, orosomucoid 1 (ORMI), and Ig lambda-2 chain C regions (IGLC2) as protein markers in a urine sample from a subject.
    Type: Grant
    Filed: June 12, 2017
    Date of Patent: June 8, 2021
    Assignees: INSTYTUT BIOCHEMII I BIOFIZYKI POLSKIEJ AKADEMII NAUK, WARSZAWSKI UNIWERSYTET MEDYCZNY
    Inventors: Krzysztof Mucha, Leszek Paczek, Radoslaw Zagozdzon, Bartosz Foroncewicz, Michal Dadlez, Magdalena Bakun, Jan Piwowarski, Tomas Pilzys, Michal Marcinkowski, Damian Garbicz, Elzbieta Grzesiuk, Michal Florczak
  • Method of evaluating the therapeutic efficacy of bacteriophages
    Patent number: 9678063
    Abstract: The subject of the present invention is a novel use of a nematode in the evaluation of the therapeutic efficacy of bacteriophage preparations used in, or capable of being used in the treatment of infections caused by pathogenic bacteria in humans or animals.
    Type: Grant
    Filed: July 13, 2013
    Date of Patent: June 13, 2017
    Assignees: Instytut Biochemii i Biofizyki Polskiej Akademii Nauk, Instytut Immunolii i Terapii Doswiadczalnej Polskiej Akademii Nauk, Narodowy Instytut Lekow, Szkola Gowna Gospodarstwa Wiejskiego w Warzawie, Wojskowy Instytut Higieny i Epidemiologii
    Inventors: Malgorzata Lobocka, Aleksandra Glowacka, Kamil Dabrowski, Monika S. Hejnowicz, Agnieszka Gozdek, Beata Weber-Dabrowska, Andrzej Gorski, Joanna Empel, Waleria Hryniewicz, Magdalena Kwiatek, Sylwia Parasion, Romuald Gryko
  • Method for selection of hDIS3 PIN domain inhibitors and use of hDIS3 PIN domain inhibitors for cancer treatment
    Patent number: 9611514
    Abstract: The present invention relates to a method for selection or screening of hDIS3 PIN domain inhibitors, yeast strain and cell line used in such methods It also relates to new therapeutic agents selected hDIS3 PIN domain inhibitors and uses thereof in the treatment of cancers having mutations inhDIS3 RNB domain, especially multiple myeloma. The invention also relates to composition comprising new therapeutic agent hDIS3 PIN domain inhibitor and method for inducing synthetic lethality in a cancer cell.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: April 4, 2017
    Assignees: INSTYTUT BIOCHEMII I BIOFIZYKI POLSKIEJ AKADEMII NAUK, ONCOARENDI THERAPEUTICS SP ZOO, MIEDZYNARODOWY INSTYTUT BIOLOGII MOLEKULARNEJ I KOMORKOWEJ W WARSZAWIE
    Inventors: Andrzej Dziembowski, Rafal Tomecki, Karolina Drazkowska, Roman Szczesny, Krystian Stodus, Weronika Jonko, Marcin Nowotny, Adam Golebiowski, Jacek Olczak
  • METHOD OF EVALUATING THE THERAPEUTIC EFFICACY OF BACTERIOPHAGES
    Publication number: 20150192569
    Abstract: The subject of the present invention is a novel use of a nematode in the evaluation of the therapeutic efficacy of bacteriophage preparations used in, or capable of being used in the treatment of infections caused by pathogenic bacteria in humans or animals.
    Type: Application
    Filed: July 13, 2013
    Publication date: July 9, 2015
    Applicants: Instytut Biochemii I biofizyki Polskiej Akademii Nauk, Instytut Immunologii I Terapii Doswiadczalnej Polsskiej Akademii Nauk, Narodowy instytut Lekow, Szkola Glowna Gospodarstwa Wiejskiego W Warsszawie, Wojskowy Instytut higieny I Epiemiologii
    Inventors: Malgorzata Lobocka, Aleksandra Glowacka, Kamil Dabrowski, Monika S. Hejnowicz, Agnieszka Gozdek, Beata Weber-Dabrowska, Andrzej Gorski, Joanna Empel, Waleria Hryniewicz, Magdalena Kwiatek, Sylwia Parasion, Romuald Gryko
  • METHODS OF TREATING VIRAL INFECTIONS WITH ANTHRACYCLINE ANTIBIOTICS
    Publication number: 20090298786
    Abstract: A method of treating hepatitis C viral infection or viremia in a patient by administering to the patient an anti-hepatitis C virally effective amount of a compound of Formula 1 or Formula 2. A method for inhibiting the replication of hepatitis C virus by exposing the virus to a hepatitis C viral NS3 protease inhibiting amount of: a compound of Formula 1 or Formula 2. A pharmaceutical composition exhibiting an antihelicase activity containing at least a pharmaceutically-acceptable carrier, diluent or excipient, and a compound of Formula 1 or Formula 2. The pharmaceutical composition may additionally contain a second compound of Formula 1 or Formula 2; epidoxorubicin, doxorubicin, epidaunorubicin, or daunorubicin; and/or another antiviral agent.
    Type: Application
    Filed: August 7, 2009
    Publication date: December 3, 2009
    Applicants: INSTYTUT BIOTECHNOLOGII I ANTYBIOTYKOW, INSTYTUT BIOCHEMII I BIOFIZYKI POLSKIEJ AKADEMII NAUK
    Inventors: Irena OSZCZAPOWICZ, Anna BOGUSZEWSKA-CHACHULSKA, Mariusz KRAWCZYK, Malgorzata LUKAWSKA