Patents Assigned to Intergen Company, L.P.
  • Pyrimidines linked to a quencher
    Patent number: 6117986
    Abstract: Compounds are described comprising pyrimidines substituted at the C-5 position with a linker and quencher. These compounds when incorporated into hairpin oligonucleotides quench the fluorescence of fluorophores linked to the 5'-terminus of the oligonucleotide. These nucleotide-quencher compounds are also easy to incorporate into oligonucleotides using conventional, automated, oligonucleotide synthetic techniques.
    Type: Grant
    Filed: June 10, 1998
    Date of Patent: September 12, 2000
    Assignee: Intergen Company, L.P.
    Inventors: Glenn Nardone, Irena Nazarenko, Jila Boal