Patents Assigned to INTERNATIONAL PARK OF CREATIVITY
  • Patent number: 10501815
    Abstract: Described herein are glucose and insulin sensors. The sensors are composed of host cells with DNA specifically designed to produce fluorescence when the cells come into contact with glucose and/or insulin in the sample. Once the fluorescence has been quantified, it can be correlated with the amount of glucose and/or insulin present in the sample.
    Type: Grant
    Filed: April 2, 2018
    Date of Patent: December 10, 2019
    Assignee: International Park of Creativity
    Inventor: Raul Cuero Rengifo
  • Publication number: 20180223379
    Abstract: Described herein are glucose and insulin sensors. The sensors are composed of host cells with DNA specifically designed to produce fluorescence when the cells come into contact with glucose and/or insulin in the sample. Once the fluorescence has been quantified, it can be correlated with the amount of glucose and/or insulin present in the sample.
    Type: Application
    Filed: April 2, 2018
    Publication date: August 9, 2018
    Applicant: INTERNATIONAL PARK OF CREATIVITY
    Inventor: Raul CUERO RENGIFO
  • Patent number: 10011841
    Abstract: Described herein are methods and devices for ligating nucleic acids or nucleic acid fragments as well as methods for transforming or transfecting cells with exogenous DNA. The methods and devices generally involve exposing the nucleic acids, nucleic acid fragments, and/or cells to an electromagnetic field, for example, a mini-current electromagnetic field, while performing the steps of ligation or transformation. The methods and devices provide numerous advantages over conventional ligation and transformation techniques and systems such as reduced reaction times, no heating requirements, and reduced amounts of reagents. Finally, as shown in the examples below, the methods and devices described herein are more effective compared to conventional ligation and transformation techniques and systems.
    Type: Grant
    Filed: July 31, 2014
    Date of Patent: July 3, 2018
    Assignee: International Park of Creativity
    Inventors: Raul Cuero Rengifo, Natalia Gutierrez Calle, Mariana Sanchez Londono
  • Patent number: 9932644
    Abstract: Described herein are glucose and insulin sensors. The sensors are composed of host cells with DNA specifically designed to produce fluorescence when the cells come into contact with glucose and/or insulin in the sample. Once the fluorescence has been quantified, it can be correlated with the amount of glucose and/or insulin present in the sample.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: April 3, 2018
    Assignee: International Park of Creativity
    Inventors: Raul Cuero Rengifo, Juliana Maria Navia
  • Patent number: 9890201
    Abstract: Described herein are devices and methods for simultaneously expressing amyloid precursor protein and TonB protein. For example, the biological devices and methods described herein increase the production of these two proteins while also reducing the cost, making these proteins more widely accessible for medical research purposes, including for the development of diagnostic tests for Alzheimer's disease. The amyloid precursor protein and TonB protein produced by the devices and methods described herein, as well as the devices themselves, can be used in experiments designed to model the interactions between metals and ?-amyloid that are characteristic of Alzheimer's disease.
    Type: Grant
    Filed: August 4, 2014
    Date of Patent: February 13, 2018
    Assignee: International Park of Creativity
    Inventors: Raul Cuero Rengifo, Diana Marcela Vasquez Forero
  • Patent number: 9868811
    Abstract: Described herein are polyurethane compositions based on natural materials, as well as methods for making and using the compositions. Also described herein are biofoams made from the polyurethane compositions. The biofoams described herein are resistant to degradation by acid and heat and are able to recover their original shapes after the application of pressure.
    Type: Grant
    Filed: August 4, 2014
    Date of Patent: January 16, 2018
    Assignee: INTERNATIONAL PARK OF CREATIVITY
    Inventors: Raul Cuero Rengifo, Gabriela Melo Rodriguez
  • Patent number: 9828609
    Abstract: Described herein are devices and methods for enhancing the physiological properties of plants. For example, the devices and methods described herein increase the production of lycopene, which has industrial and economic value. The lycopene produced by the devices and methods does not require the ultra purification that is common in conventional or commercial methods. The devices and methods described herein also enhance the growth rate of plants.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: November 28, 2017
    Assignee: International Park of Creativity
    Inventor: Raul Cuero Rengifo
  • Publication number: 20170240979
    Abstract: Described herein are glucose and insulin sensors. The sensors are composed of host cells with DNA specifically designed to produce fluorescence when the cells come into contact with glucose and/or insulin in the sample. Once the fluorescence has been quantified, it can be correlated with the amount of glucose and/or insulin present in the sample.
    Type: Application
    Filed: April 27, 2017
    Publication date: August 24, 2017
    Applicant: INTERNATIONAL PARK OF CREATIVITY
    Inventors: Raul CUERO RENGIFO, Juliana Maria Navia
  • Patent number: 9683266
    Abstract: Described herein are glucose and insulin sensors. The sensors are composed of host cells with DNA specifically designed to produce fluorescence when the cells come into contact with glucose and/or insulin in the sample. Once the fluorescence has been quantified, it can be correlated with the amount of glucose and/or insulin present in the sample.
    Type: Grant
    Filed: April 19, 2012
    Date of Patent: June 20, 2017
    Assignee: INTERNATIONAL PARK OF CREATIVITY
    Inventors: Raul Cuero Rengifo, Juliana Maria Navia
  • Publication number: 20160168214
    Abstract: Described herein are devices and methods for simultaneously expressing amyloid precursor protein and TonB protein. For example, the biological devices and methods described herein increase the production of these two proteins while also reducing the cost, making these proteins more widely accessible for medical research purposes, including for the development of diagnostic tests for Alzheimer's disease. The amyloid precursor protein and TonB protein produced by the devices and methods described herein, as well as the devices themselves, can be used in experiments designed to model the interactions between metals and ?-amyloid that are characteristic of Alzheimer's disease.
    Type: Application
    Filed: August 4, 2014
    Publication date: June 16, 2016
    Applicant: INTERNATIONAL PARK OF CREATIVITY
    Inventors: Raul Cuero RENGIFO, Diana Marcela VASQUEZ FORERO
  • Publication number: 20160168311
    Abstract: Described herein are polyurethane compositions based on natural materials, as well as methods for making and using the compositions. Also described herein are biofoams made from the polyurethane compositions. The biofoams described herein are resistant to degradation by acid and heat and are able to recover their original shapes after the application of pressure.
    Type: Application
    Filed: August 4, 2014
    Publication date: June 16, 2016
    Applicant: INTERNATIONAL PARK OF CREATIVITY
    Inventors: Raul CUERO RENGIFO, Gabriela MELO RODRIGUEZ
  • Publication number: 20160109339
    Abstract: Described herein are compositions and methods for effectively removing from soil samples. By isolating the oil from the soil sample, it is possible to accurately evaluate the different properties of the oil in the sample.
    Type: Application
    Filed: May 21, 2014
    Publication date: April 21, 2016
    Applicant: INTERNATIONAL PARK OF CREATIVITY
    Inventors: Raul CUERO RENGIFO, Jhon Henry TRUJILLO MONTENEGRO, Jennifer Melissa RUSSI CASTILLO, Mauricio CASTILLO PALACIOS
  • Publication number: 20160017362
    Abstract: Described herein are devices and methods for enhancing the physiological properties of plants. For example, the devices and methods described herein increase the production of lycopene, which has industrial and economic value. The lycopene produced by the devices and methods does not require the ultra purification that is common in conventional or commercial methods. The devices and methods described herein also enhance the growth rate of plants.
    Type: Application
    Filed: March 11, 2014
    Publication date: January 21, 2016
    Applicant: INTERNATIONAL PARK OF CREATIVITY
    Inventors: Raul CUERO RENGIFO, Maria ALEJANDRA CABRERA DELGADO
  • Patent number: 9044729
    Abstract: Methods and devices for amplifying nucleic acids generally involve exposing the nucleic acid to an electromagnetic field, for example a mini-current magnetic field, while performing the steps of PCR. The PCR methods and devices provide numerous advantages over conventional PCR techniques and systems such as reduced reaction times, no heating requirements, and reduced amounts of reagents (e.g., optional use polymerases and primers). Additionally, the PCR methods and devices require significantly shorter reaction times (e.g., less than one hour) compared to conventional PCR techniques and systems (minimum 2 hours). Finally, as shown in the Examples, the PCR methods and devices amplify significantly more DNA compared to conventional PCR techniques and systems. Accordingly, the PCR methods and devices provide a more efficient and cost-effective way to perform PCR when compared to conventional PCR techniques and systems.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: June 2, 2015
    Assignee: International Park of Creativity
    Inventors: Raul Cuero Rengifo, Mario Antonio Franco Jimenez, Natalia Gutierrez Calle, Mariana Sanchez Londono
  • Publication number: 20140287425
    Abstract: Described herein are glucose and insulin sensors. The sensors are composed of host cells with DNA specifically designed to produce fluorescence when the cells come into contact with glucose and/or insulin in the sample. Once the fluorescence has been quantified, it can be correlated with the amount of glucose and/or insulin present in the sample.
    Type: Application
    Filed: April 19, 2012
    Publication date: September 25, 2014
    Applicant: INTERNATIONAL PARK OF CREATIVITY
    Inventors: Raul Cuero Rengifo, Juliana Maria Navia
  • Publication number: 20140030764
    Abstract: Methods and devices for amplifying nucleic acids generally involve exposing the nucleic acid to an electromagnetic field, for example a mini-current magnetic field, while performing the steps of PCR. The PCR methods and devices provide numerous advantages over conventional PCR techniques and systems such as reduced reaction times, no heating requirements, and reduced amounts of reagents (e.g., optional use polymerases and primers). Additionally, the PCR methods and devices require significantly shorter reaction times (e.g., less than one hour) compared to conventional PCR techniques and systems (minimum 2 hours). Finally, as shown in the Examples, the PCR methods and devices amplify significantly more DNA compared to conventional PCR techniques and systems. Accordingly, the PCR methods and devices provide a more efficient and cost-effective way to perform PCR when compared to conventional PCR techniques and systems.
    Type: Application
    Filed: March 15, 2013
    Publication date: January 30, 2014
    Applicant: INTERNATIONAL PARK OF CREATIVITY
    Inventors: Raul Cuero RENGIFO, Mario Antonio FRANCO JIMENEZ, Natalia GUTIERREZ CALLE, Mariana SANCHEZ LONDONO