Patents Assigned to International Partnership For Microbicides, Inc.
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Patent number: 11259956Abstract: The present invention provides improved intravaginal drug delivery devices, i.e., intravaginal rings, useful for the prophylactic administration of dapivirine in combination with either an antimicrobial compound or a contraceptive to a human. The present invention also provides methods of blocking DNA polymerization by an HIV reverse transcriptase enzyme, methods of preventing HIV infection in a female human, methods of treating HIV infection in a female human, methods of preventing unintended pregnancy in a female human, and methods of preparing intravaginal rings.Type: GrantFiled: October 9, 2018Date of Patent: March 1, 2022Assignee: International Partnership for Microbicides, Inc.Inventors: Brid Devlin, Jonathon Daryll Holt, Andrew Nathan Brimer, Jeremy Peter Nuttall, Karl Malcolm, Susan Margaret Fetherston, Peter John James Boyd
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Patent number: 10137031Abstract: The present invention provides improved intravaginal drug delivery devices, i.e., intravaginal rings, useful for the prophylactic administration of dapivirine in combination with either an antimicrobial compound or a contraceptive to a human. The present invention also provides methods of blocking DNA polymerization by an HIV reverse transcriptase enzyme, methods of preventing HIV infection in a female human, methods of treating HIV infection in a female human, methods of preventing unintended pregnancy in a female human, and methods of preparing intravaginal rings.Type: GrantFiled: November 13, 2014Date of Patent: November 27, 2018Assignee: International Partnership for Microbicides, Inc.Inventors: Brid Devlin, Jonathon Daryll Holt, Andrew Nathan Brimer, Jeremy Peter Nuttall, Karl Malcolm, Susan Margaret Fetherston, Peter John James Boyd
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Patent number: 9283182Abstract: The present invention relates to formulations of nucleotide reverse transcriptase inhibitors (NRTIs), preferably [2-(6-Amino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid (tenofovir, PMPA), or a physiologically functional derivative thereof, suitable for topical application and their use in the prevention of HIV infections.Type: GrantFiled: September 24, 2010Date of Patent: March 15, 2016Assignees: The CONRAD Program of the Eastern Virginia Medical School (“CONRAD”), International Partnership for Microbicides, Inc.Inventor: Terrence C. Dahl
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Patent number: 9060933Abstract: The present invention relates to formulations of nucleotide reverse transcriptase inhibitors (NRTIs), preferably [2-(6-Amino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid (tenofovir, PMPA), or a physiologically functional derivative thereof, suitable for topical application and their use in the prevention of HIV infections.Type: GrantFiled: September 29, 2010Date of Patent: June 23, 2015Assignees: The CONRAD Program of the Eastern Virginia Medical School (“CONRAD”), International Partnership for Microbicides, Inc.Inventor: Terrence C. Dahl
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Publication number: 20110132376Abstract: The present invention relates to formulations of nucleotide reverse transcriptase inhibitors (NRTIs), preferably [2-(6-Amino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid (tenofovir, PMPA), or a physiologically functional derivative thereof, suitable for topical application and their use in the prevention of HIV infections.Type: ApplicationFiled: September 29, 2010Publication date: June 9, 2011Applicants: Conrad, International Partnership for Microbicides, Inc.Inventor: Terrence C. Dahl
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Publication number: 20110120475Abstract: The present invention relates to formulations of nucleotide reverse transcriptase inhibitors (NRTIs), preferably [2-(6-Amino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid (tenofovir, PMPA), or a physiologically functional derivative thereof, suitable for topical application and their use in the prevention of HIV infections.Type: ApplicationFiled: September 24, 2010Publication date: May 26, 2011Applicants: Conrad, International Partnership for Microbicides, Inc.Inventor: Terrence C. Dahl
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Publication number: 20100316691Abstract: The present disclosure relates to biodegradable intravaginal rings for the delivery of therapeutic or prophylactic agent, inter alia, antiviral agents. The present disclosure further relates to biodegradable polyurethanes which will allow therapeutic/prophylactic agents to be released in a controlled manner that will not degrade when in use, but will degrade upon disposal.Type: ApplicationFiled: January 22, 2008Publication date: December 16, 2010Applicants: University of Utah Research Foundation, International Partnership For Microbicides, Inc.Inventors: Patrick Kiser, Patrick Tresco, Mark Mitchnick, Kavita Gupta, Hyder Aliyar