Patents Assigned to IntraBiotics Pharmaceuticals, Inc.
  • Protegrins
    Patent number: 6653442
    Abstract: Peptide-based compounds containing four invariant cysteine residues which have been optionally oxidized to contain two intramolecular disulfide bonds, or modified forms where the cysteines are replaced are useful as preservatives and in preventing, treating, or ameliorating viral or microbial infection in animals and plants, and in inactivating endotoxin.
    Type: Grant
    Filed: August 30, 1999
    Date of Patent: November 25, 2003
    Assignee: IntraBiotics Pharmaceuticals, Inc.
    Inventors: Conway C. Chang, Chee L. Gu, Jie Chen, Deborah A. Steinberg, Robert I. Lehrer, Sylvia S. L. Harwig, Vladimir N. Kokryakov
  • Parevins and tachytegrins
    Publication number: 20020147301
    Abstract: The present invention provides a new class of broad-spectrum antimicrobial peptides effective against a wide variety of microbes, including bacteria, viruses, retroviruses, fungi, yeast and protozoa.
    Type: Application
    Filed: May 24, 2001
    Publication date: October 10, 2002
    Applicant: IntraBiotics Pharmaceuticals, Inc.
    Inventors: Robert I. Lehrer, Sylvia S.L. Harwig, Conway C. Chang, Chee L. Gu
  • Parevins and tachytegrins
    Patent number: 6307016
    Abstract: The present invention provides a new class of broad-spectrum antimicrobial peptides effective against a wide variety of microbes, including bacteria, viruses, retroviruses, fungi, yeast and protozoa.
    Type: Grant
    Filed: August 3, 1998
    Date of Patent: October 23, 2001
    Assignee: IntraBiotics Pharmaceuticals, Inc.
    Inventors: Robert I. Lehrer, Sylvia S. L. Harwig, Conway C. Chang, Chee L. Gu
  • Threonine-containing protegrins
    Patent number: 6043220
    Abstract: The invention is directed to antimicrobial peptides related to naturally-occurring protegrin peptides, and methods of using the peptides in a variety of contexts, including the treatment or prevention of infections, and diseases related thereto.
    Type: Grant
    Filed: December 3, 1997
    Date of Patent: March 28, 2000
    Assignee: IntraBiotics Pharmaceuticals, Inc.
    Inventors: Conway C. Chang, Jie Chen, Robert I. Lehrer, Peggy A. Radel
  • Compositions and methods for the prevention and treatment of oral mucositis
    Patent number: 6025326
    Abstract: The present invention provides methods and compositions suitable for treating oral mucositis in animals, including humans, with antimicrobial peptides such as protegrin peptides.
    Type: Grant
    Filed: November 21, 1996
    Date of Patent: February 15, 2000
    Assignee: IntraBiotics Pharmaceuticals, Inc.
    Inventors: Deborah A. Steinberg, De Hwa Chao, David J. Loury, Roger Cherng Fu, Chee Liang Gu, Conway C. Chang, John C. Fiddes
  • Fine-tuned protegrins
    Patent number: 5994306
    Abstract: The invention is directed to antimicrobial peptides related to naturally-occurring protegrin peptides, and methods of using the peptides in a variety of contexts, including the treatment or prevention of infections.
    Type: Grant
    Filed: November 21, 1996
    Date of Patent: November 30, 1999
    Assignee: IntraBiotics Pharmaceuticals, Inc.
    Inventors: Conway C. Chang, Chee Liang Gu, Jie Chen, Deborah A. Steinberg, Robert I. Lehrer, Sylvia S.L. Harwig, deceased
  • Cyclic peptides having broad spectrum antimicrobial activity
    Patent number: 5916872
    Abstract: The present invention provides cyclic peptides having broad spectrum antimicrobial activity. The peptides exhibit improved efficacy, bioavailability and/or serum half-life as compared with non-cyclized analogues.
    Type: Grant
    Filed: July 24, 1996
    Date of Patent: June 29, 1999
    Assignee: IntraBiotics Pharmaceuticals, Inc.
    Inventors: Conway Chang, Leo Gu, Jie Chen
  • Parevins and tachytegrins
    Patent number: RE38828
    Abstract: The present invention provides a new class of broad-spectrum antimicrobial peptides effective against a wide variety of microbes, including bacteria, viruses, retroviruses, fungi, yeast and protozoa.
    Type: Grant
    Filed: September 24, 2002
    Date of Patent: October 11, 2005
    Assignee: IntraBiotics Pharmaceuticals, Inc.
    Inventors: Robert I. Lehrer, Sylvia S. L. Harwig, Conway C. Chang, Chee L. Gu