Abstract: The present invention provides antibodies that specifically bind to P2X7 receptors and distinguish between function and non-functional P2X7 receptors, pharmaceutical compositions and kits containing the antibodies, and methods of using the antibodies for the detection, diagnosis and treatment of disease conditions.
Type:
Application
Filed:
December 21, 2010
Publication date:
April 21, 2011
Applicant:
Intreat Pty Limited
Inventors:
Julian Alexander Barden, Angus Gidley-Baird
Abstract: The present invention provides antibodies that specifically bind to P2X7 receptors and distinguish between function and non-functional P2X7 receptors, pharmaceutical compositions and kits containing the antibodies, and methods of using the antibodies for the detection, diagnosis and treatment of disease conditions.
Type:
Grant
Filed:
April 3, 2009
Date of Patent:
February 15, 2011
Assignee:
Intreat Pty Limited
Inventors:
Julian Alexander Barden, Angus Gidley-Baird
Abstract: The present invention provides antibodies that specifically bind to P2X7 receptors and distinguish between function and non-functional P2X7 receptors, pharmaceutical compositions and kits containing the antibodies, and methods of using the antibodies for the detection, diagnosis and treatment of disease conditions.
Type:
Application
Filed:
April 3, 2009
Publication date:
July 30, 2009
Applicant:
Intreat Pty Limited
Inventors:
Julian Alexander BARDEN, Angus Gidley-Baird
Abstract: The present invention provides antibodies that specifically bind to P2X7 receptors and distinguish between function and non-functional P2X7 receptors, pharmaceutical compositions and kits containing the antibodies, and methods of using the antibodies for the detection, diagnosis and treatment of disease conditions.
Type:
Grant
Filed:
January 2, 2008
Date of Patent:
May 12, 2009
Assignee:
Intreat Pty Limited
Inventors:
Julian Alexander Barden, Angus Gidley-Baird
Abstract: The present invention provides antibodies that specifically bind to P2X7 receptors and distinguish between function and non-functional P2X7 receptors, pharmaceutical compositions and kits containing the antibodies, and methods of using the antibodies for the detection, diagnosis and treatment of disease conditions.
Type:
Application
Filed:
January 2, 2008
Publication date:
June 5, 2008
Applicant:
Intreat Pty Limited
Inventors:
Julian Alexander Barden, Angus Gidley-Baird
Abstract: The present invention provides antibodies that specifically bind to P2X7 receptors and distinguish between functional and non-functional P2X7 receptors, pharmaceutical compositions and kits containing the antibodies, and methods of using the antibodies for the detection, diagnosis and treatment of disease conditions.
Type:
Grant
Filed:
July 17, 2003
Date of Patent:
February 5, 2008
Assignee:
Intreat Pty Limited
Inventors:
Julian Alexander Barden, Angus Gidley-Baird
Abstract: The invention concerns a wide range of diseases and conditions, including cancers. The invention provides a probe for detection of such a disease or condition. The probe is able to distinguish between functional P2X7 receptors and non-functional P2X7 receptors. The probe can do this in various ways, one of which is detecting change in relation to binding of adenosine triphosphate (ATP) to the receptors.
Type:
Application
Filed:
July 17, 2003
Publication date:
July 22, 2004
Applicant:
Intreat Pty Limited
Inventors:
Julian Alexander Barden, Angus Gidley-Baird