Abstract: An image analysis workstation for analyzing optical thin film arrays is disclosed. One disclosed embodiment relates to individual arrays that comprise a single optical thin film test surface that provides a plurality of discretely addressable locations, each comprising an immobilized capture reagent for an analyte of interest. These are referred to herein as “arrayed optical thin film test surfaces.” Preferably, an individual arrayed optical thin film test surface comprises at least 4, more preferably at least 16, even more preferably at least 32, still more preferably at least 64, and most preferably 128 or more discretely addressable locations. One or more of the discretely addressable locations may provide control signals (e.g., for normalizing signals and/or that act as positive and/or negative controls) or fiducial signals (i.e., information that is used to determine the relative alignment of the arrayed optical thin film test surface within the device.
Type:
Grant
Filed:
April 16, 2003
Date of Patent:
April 21, 2009
Assignee:
Inverness Medical-Biostar, Inc.
Inventors:
Larry Rea, David D. Clark, Rob Jenison, Diana Maul
Abstract: An optical assay device for the detection of an analyte of interest in a sample comprising a support containing channels, an optically functional layer positioned on the support such that the optically functional layer and the support allow for laminar flow of the sample through layers of the device, an attachment layer positioned on the optically functional layer, and an analyte specific receptive layer positioned on the attachment layer.
Type:
Grant
Filed:
October 15, 1997
Date of Patent:
December 26, 2006
Assignee:
Inverness Medical - Biostar, Inc.
Inventors:
Joel A. Drewes, Gregory R. Bogart, Jeffrey B. Etter, Jeffrey W. Steaffens, Rachel M. Ostroff, Mark Crosby