Abstract: A composition formulated for diversion- and/or abuse-resistance, includes at least one active pharmaceutical ingredient (API), each present in an acidic form, a first compound capable of coupling to the acidic form of the API to form a complex, where the resulting complex is resistant to separation by conventional separation methods, and a second compound capable of preferentially coupling to the first compound to thereby release the API from the complex.
Type:
Grant
Filed:
August 5, 2015
Date of Patent:
May 16, 2017
Assignee:
Invincible Biotechnology, LLC
Inventors:
Vadim Zolotarsky, Alexandr Vasilievich Troitsky, Michael Libman, Mikhail Viktorovich Losev
Abstract: A composition formulated for diversion- and/or abuse-resistance, includes at least one active pharmaceutical ingredient (API), each present in an acidic form, a first compound capable of coupling to the acidic form of the API to form a complex, where the resulting complex is resistant to separation by conventional separation methods, and a second compound capable of preferentially coupling to the first compound to thereby release the API from the complex.
Type:
Application
Filed:
August 5, 2015
Publication date:
November 26, 2015
Applicant:
Invincible Biotechnology, LLC
Inventors:
Vadim ZOLOTARSKY, Alexandr Vasilievich TROITSKY, Michael LIBMAN, Mikhail Viktorovich LOSEV